Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hanneke J. A. A. van Zoggel"'
Autor:
Petra W van Duijn, Cor A. Berrevoets, Angelique C.J. Ziel-van der Made, Ashraf Aghai, Wytske M. van Weerden, Guido Jenster, Rute B. Marques, Jan Trapman, Reno Debets, Hanneke J. A. A. van Zoggel
Publikováno v:
Prostate, 78(13), 1013-1023. Wiley-Liss Inc.
Background Prostate cancer is recognized as a heterogeneous disease demanding appropriate preclinical models that reflect tumor complexity. Previously, we established the PSA-Cre;PtenLoxP/LoxP genetic engineered mouse model (GEMM) for prostate cancer
Autor:
Emmy W. Verschuren, Vítor E. Santo, Meng Dong, Erwin R. Boghaert, Katja Närhi, Wolfgang Sommergruber, Kjersti Gjerde, Suzana Vidic, Annika Osswald, Hanneke J. A. A. van Zoggel, Sami Blom, Emma J. Davies, Ronald de Hoogt, Marta Estrada, Yolanda T. Chong, Ralph Graeser, John A. Hickman, Heiko van der Kuip, Wytske M. van Weerden, Catarina Brito, Michaël Barbier
Publikováno v:
Scientific Data
Scientific data, 4:170170. Nature Publishing Group
Scientific data, 4:170170. Nature Publishing Group
Two-dimensional (2D) culture of cancer cells in vitro does not recapitulate the three-dimensional (3D) architecture, heterogeneity and complexity of human tumors. More representative models are required that better reflect key aspects of tumor biolog
Autor:
Julia Schueler, Simon T. Barry, Riku Turkki, Taija af Hällström, Tauno Metsalu, Emmy W. Verschuren, Wytske M. van Weerden, Sigrun Erkens-Schulze, Meng Dong, John A. Hickman, Heiko van der Kuip, Eva Oswald, Katja Närhi, Hanneke J. A. A. van Zoggel, Ashwini S. Nagaraj, Matthias Gutekunst, Sami Blom, Emma J. Davies, Juan A. Delgado San Martin, Stephen R. Wedge
Publikováno v:
Scientific Reports
Scientific Reports, 5. Nature Publishing Group
Scientific Reports, 5. Nature Publishing Group
Precision-cut slices of in vivo tumours permit interrogation in vitro of heterogeneous cells from solid tumours together with their native microenvironment. They offer a low throughput but high content in vitro experimental platform. Using mouse mode