Výsledky vyhledávání - "Hanneke Boon"

Altered content of AMP-activated protein kinase isoforms in skeletal muscle from spinal cord injured subjects

Autor: Ulrika Widegren, Maria Ahlsén, Anna Krook, Hanneke Boon, Emil Kostovski, Per Ole Iversen, Leonidas S. Lundell, Alexander V. Chibalin, Nils Hjeltnes

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 305:E1071-E1080

AMP-activated protein kinase (AMPK) is a pivotal regulator of energy homeostasis. Although downstream targets of AMPK are widely characterized, the physiological factors governing isoform expression of this protein kinase are largely unknown. Nerve/c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6116c40bdad20510b1a21349c31508f
https://doi.org/10.1152/ajpendo.00132.2013

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Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance

Autor: Bas Havekes, Gijs H. Goossens, Matthew J. Watt, Hanneke Boon, Yvonne P. G. Essers, Luc J. C. van Loon, Rachael R. Mason, Johan W. E. Jocken, Ellen E. Blaak

Publikováno v: Diabetologia, 56(10), 2255-2265. Springer, Cham
Diabetologia

Aims/hypothesis Impaired regulation of lipolysis and accumulation of lipid intermediates may contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated insulin-mediated suppression of lipolysis in abdominal subcuta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f9503fa57beb47704b3a87bfbe6816
https://doi.org/10.1007/s00125-013-2995-9

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Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training

Autor: Séverine Lamon, Glenn D. Wadley, Hanneke Boon, Takayuki Akimoto, Erin L. Brown, Shogo Wada, Alexander V. Chibalin, Rodney J. Snow, Juleen R. Zierath, Isabelle Guller, Aaron P. Russell, Nigel K. Stepto

Publikováno v: The Journal of Physiology. 591:4637-4653

Key points • The discovery of microRNAs (miRNAs) has established new mechanisms that control health, but little is known about the regulation of skeletal muscle miRNAs in response to exercise. • This study investigated components of the miRNA bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1640b0c92808d51f8f2196789e67b5ff
https://doi.org/10.1113/jphysiol.2013.255695

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Influence of chronic and acute spinal cord injury on skeletal muscle Na+-K+-ATPase and phospholemman expression in humans

Autor: Moshi Song, Alexander V. Chibalin, Sergej Pirkmajer, Emil Kostovski, Ulrika Widegren, Hanneke Boon, Per Ole Iversen, Nils Hjeltnes, Irina Lubarski

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 302:E864-E871

Na+-K+-ATPase is an integral membrane protein crucial for the maintenance of ion homeostasis and skeletal muscle contractibility. Skeletal muscle Na+-K+-ATPase content displays remarkable plasticity in response to long-term increase in physiological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6b6bf7f0410f8b544f709a355ad672
https://doi.org/10.1152/ajpendo.00625.2011

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Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists

Autor: L.J.C. van Loon, Hanneke Boon, Luke Norton, Joost J. F. P. Luiken, Kostas Tsintzas, Jan F. C. Glatz, K. Jewell, Maurice M.A.L. Pelsers

Publikováno v: Acta Physiologica, 190(3), 209-219. Wiley-Blackwell

Aim: Membrane fatty acid transporters can modulate the balance between fatty acid uptake and subsequent storage and/or oxidation in muscle tissue. As such, skeletal muscle fatty acid transporter protein expression could play an important role in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb9fe96df708f461de2fc23fe93942a
https://doi.org/10.1111/j.1748-1716.2007.01698.x

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Carbohydrate supplementation during prolonged cycling exercise spares muscle glycogen but does not affect intramyocellular lipid use

Autor: Harm Kuipers, Trent Stellingwerff, Hanneke Boon, Annemie P. Gijsen, Jos H. C. H. Stegen, Luc J. C. van Loon

Publikováno v: Pflugers Archiv
Pflugers Archiv-European Journal of Physiology, 454(4), 635-647. Springer Verlag

Using contemporary stable-isotope methodology and fluorescence microscopy, we assessed the impact of carbohydrate supplementation on whole-body and fiber-type-specific intramyocellular triacylglycerol (IMTG) and glycogen use during prolonged enduranc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3999e6f5114653b574ca5c70537fd50
https://doi.org/10.1007/s00424-007-0236-0

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Significant intramyocellular lipid use during prolonged cycling in endurance trained males as assessed by three different methodologies

Autor: Trent Stellingwerff, Joan M. G. Senden, Hanneke Boon, Luc J. C. van Loon, Lawrence L. Spriet, René Koopman, Richard A. M. Jonkers

Publikováno v: American Journal of Physiology : Endocrinology and Metabolism, 292(6), E1715-E1723. American Physiological Society

Intramyocellular triacylglycerol (IMTG) has been suggested to represent an important substrate source during exercise. In the present study, IMTG utilization during exercise is assessed through the use of various methodologies. In addition, we identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7443bae9e25474755694980937e11e
https://cris.maastrichtuniversity.nl/en/publications/a4158b10-5c32-4bf8-8bb0-58d5413f1165

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MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression

Autor: Juleen R. Zierath, Hanneke Boon, Ulrika Widegren, Rasmus J. O. Sjögren, Julie Massart, Emil Kostovski, Nils Hjeltnes, Brendan Egan, Per Ole Iversen, Alexander V. Chibalin

Publikováno v: Physiological Reports

The effects of long-term physical inactivity on the expression of microRNAs involved in the regulation of skeletal muscle mass in humans are largely unknown. MicroRNAs are short, noncoding RNAs that fine-tune target expression through mRNA degradatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8df9324c033f06becf46dc297595d0
http://europepmc.org/articles/PMC4673649

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Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training

Autor: Aaron P, Russell, Severine, Lamon, Hanneke, Boon, Shogo, Wada, Isabelle, Güller, Erin L, Brown, Alexander V, Chibalin, Juleen R, Zierath, Rod J, Snow, Nigel, Stepto, Glenn D, Wadley, Takayuki, Akimoto

Publikováno v: The Journal of physiology. 591(18)

The identification of microRNAs (miRNAs) has established new mechanisms that control skeletal muscle adaptation to exercise. The present study investigated the mRNA regulation of components of the miRNA biogenesis pathway (Drosha, Dicer and Exportin-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a4563e58cbc1db03c40a18064058db7c
https://pubmed.ncbi.nlm.nih.gov/23798494

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Differential expression of metabolic genes essential for glucose and lipid metabolism in skeletal muscle from spinal cord injured subjects

Autor: Nils Hjeltnes, Hanneke Boon, Ulrika Widegren, Emil Kostovski, Anna Krook, Yun Chau Long

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 110(5)

Skeletal muscle plays an important role in the regulation of energy homeostasis; therefore, the ability of skeletal muscle to adapt and alter metabolic gene expression in response to changes in physiological demands is critical for energy balance. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac1328ff8a5533da3b019c7b45eb410
https://pubmed.ncbi.nlm.nih.gov/21393466

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