Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hanne Skovsgaard Pedersen"'
Autor:
Christoffer Laustsen, Anne M. Landau, Margarita Melnikova Joergensen, Marianne Lundsgaard Kristensen, Olav M. Andersen, Ida Elisabeth Holm, Lars Friis Mikkelsen, Nikolaj Boegh, Mathias Droescher, Giulia Monti, Hanne Skovsgaard Pedersen, Lars Bolund, Henrik Callesen, Benedicte Parm Ulhoei, Charlotte Brandt Soerensen, Kirsten Rosenmay Jacobsen, Scott A. Small, Laura Breidenbach, Anne Mette G. Jensen, Jens R. Nyengaard, Gro Grunnet Ploeen, Esben Søvsø Szocska Hansen, David J. Brooks, Ying Liu, Charlotte E. Teunissen, Yonglun Luo
The few established causal genes in Alzheimer’s disease (AD), mutations in APP and PSENs, have been functionally characterized using biomarkers, capturing an in vivo profile reflecting the disease’s initial preclinical phase. SORL1, a gene encodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87bb3d517054a38de8863ae1ace630b
https://doi.org/10.1101/2021.07.13.452149
https://doi.org/10.1101/2021.07.13.452149
Autor:
Hanne Skovsgaard Pedersen, Nick S. Laursen, Gregers R. Andersen, Lorentzen J, Thomas Vorup-Jensen, Rasmus K. Jensen
The integrin receptor αMβ2 mediates phagocytosis of complement-opsonized objects, adhesion to the extracellular matrix and trans-endothelial migration of leukocytes. Here we present the first atomic structure of the human αMβ2 headpiece fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca9318ea616607d3a90686228971fbc
https://doi.org/10.1101/2021.07.07.451531
https://doi.org/10.1101/2021.07.07.451531
Autor:
Hanne Skovsgaard Pedersen, Martin Tang Sørensen, Henrik Callesen, Ying Liu, Knud Larsen, Leslie Foldager
Publikováno v:
Pedersen, H S, Liu, Y, Foldager, L, Callesen, H, Larsen, K E & Sørensen, M T 2019, ' Calibration of sperm concentration for in vitro fertilization in a mouse reprotoxicity model ', Toxicology in Vitro, vol. 55, pp. 58-61 . https://doi.org/10.1016/j.tiv.2018.11.009
Xenobiotics, such as chemicals and pesticides, may result in adverse effects on reproduction in human and animals. Using in-vitro embryo production as a testing system reveals details of fertilization (IVF) and early embryonic development (IVC). The
Autor:
Giulia Monti, Lars Friis Mikkelsen, Marianne Lundsgaard Kristensen, Kirsten R Jacobsen, Charlotte E. Teunissen, David J. Brooks, Lars Bolund, Anne M. Landau, Christoffer Laustsen, Scott A. Small, Yonglun Luo, Anne Mette G. Jensen, Laura Breidenbach, Gro Grunnet Pløen, Jens R. Nyengaard, Margarita Melnikova Jørgensen, Hanne Skovsgaard Pedersen, Esben Søvsø Szocska Hansen, Charlotte S. Sørensen, Nikolaj Bøgh, Ying Liu, Mathias Droescher, Henrik Callesen, Benedicte Parm Ulhøi, Ida Elisabeth Holm, Olav M. Andersen
Publikováno v:
SSRN Electronic Journal.
The few established causal genes in Alzheimer’s disease (AD), mutations in APP and PSENs, have been functionally characterized using biomarkers, capturing an in vivo profile reflecting the disease’s initial preclinical phase. SORL1, a gene encodi
Autor:
Henrik Callesen, Haja N. Kadarmideen, Maria Pihl, Poul Hyttel, Hanne Skovsgaard Pedersen, Gianluca Mazzoni
Publikováno v:
Pedersen, H S, Mazzoni, G, Pihl, M, Kadarmideen, H N, Hyttel, P & Callesen, H 2020, ' Bovine in-vitro produced embryos: development of embryo proper and associated membranes from day 26 to 47 of gestation ', Reproductive Biology, vol. 20, no. 4, pp. 595-599 . https://doi.org/10.1016/j.repbio.2020.10.001
Based on in-vitro produced (IVP) bovine embryos, embryo proper and embryonic/fetal membranes were studied in 12 pregnancies from day 26 to 47. The embryos/fetuses displayed external as well as internal development of organs and structures according t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6621ad9fa7e92486b9587b6a93f6bf
https://pure.au.dk/portal/da/publications/bovine-invitro-produced-embryos-development-of-embryo-proper-and-associated-membranes-from-day-26-to-47-of-gestation(fbfd8d18-116e-471a-a3bb-a77f28408167).html
https://pure.au.dk/portal/da/publications/bovine-invitro-produced-embryos-development-of-embryo-proper-and-associated-membranes-from-day-26-to-47-of-gestation(fbfd8d18-116e-471a-a3bb-a77f28408167).html
Autor:
Maria B Rabaglino, Poul Hyttel, Haja N. Kadarmideen, Gianluca Mazzoni, Hanne Skovsgaard Pedersen, Henrik Callesen
Publikováno v:
Mazzoni, G, Pedersen, H S, Rabaglino, M B, Hyttel, P, Callesen, H & Kadarmideen, H N 2020, ' Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in vitro-produced embryos ', Physiological Genomics, vol. 52, no. 7, pp. 269-279 . https://doi.org/10.1152/physiolgenomics.00027.2020
Mazzoni, G, Pedersen, H S, Rabaglino, M B, Hyttel, P, Callesen, H & Kadarmideen, H N 2020, ' Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in-vitro produced embryos ', Physiological Genomics, vol. 52, no. 7, pp. 269-279 . https://doi.org/10.1152/physiolgenomics.00027.2020
Mazzoni, G, Pedersen, H S, Rabaglino, M B, Hyttel, P, Callesen, H & Kadarmideen, H N 2020, ' Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in-vitro produced embryos ', Physiological Genomics, vol. 52, no. 7, pp. 269-279 . https://doi.org/10.1152/physiolgenomics.00027.2020
Modifications of the endometrial transcriptome at day 7 of the estrus cycle are crucial to maintain gestation after transfer of in vitro-produced (IVP) embryos, although these changes are still largely unknown. The aim of this study was to identify g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c000c78f47e6edb92977c44a16335f0d
https://curis.ku.dk/portal/da/publications/characterization-of-the-endometrial-transcriptome-in-early-diestrus-influencing-pregnancy-status-in-dairy-cattle-after-transfer-of-in-vitroproduced-embryos(a2ffc7e2-9002-4f73-b258-02636bb45a0c).html
https://curis.ku.dk/portal/da/publications/characterization-of-the-endometrial-transcriptome-in-early-diestrus-influencing-pregnancy-status-in-dairy-cattle-after-transfer-of-in-vitroproduced-embryos(a2ffc7e2-9002-4f73-b258-02636bb45a0c).html
Autor:
Maria B Rabaglino, Hanne Skovsgaard Pedersen, Henrik Callesen, Haja N. Kadarmideen, Gianluca Mazzoni, Poul Hyttel
Publikováno v:
Mazzoni, G, Pedersen, H S, Rabaglino, M B, Hyttel, P, Callesen, H & Kadarmideen, H 2020, ' Characterization of the Endometrial Transcriptome in Early Diestrus Influencing Pregnancy Establishment in Dairy Cattle after Transfer of In-Vitro Produced Embryos ', bioRxiv . https://doi.org/10.1101/2020.03.04.977082
Modifications of the endometrial transcriptome at day 7 of the estrus cycle are crucial to maintain gestation after transfer of in-vitro produced (IVP) embryos. The aim of this study was to identify genes, and their related biological mechanisms, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e55c3df760fb814768a6d3e8828520
https://pure.au.dk/portal/da/publications/characterization-of-the-endometrial-transcriptome-in-early-diestrus-influencing-pregnancy-establishment-in-dairy-cattle-after-transfer-of-invitro-produced-embryos(a27a0224-0e77-4d72-82ac-46d84e9b09ab).html
https://pure.au.dk/portal/da/publications/characterization-of-the-endometrial-transcriptome-in-early-diestrus-influencing-pregnancy-establishment-in-dairy-cattle-after-transfer-of-invitro-produced-embryos(a27a0224-0e77-4d72-82ac-46d84e9b09ab).html
Autor:
Martin Tang Sørensen, Knud Larsen, Hanne Skovsgaard Pedersen, Kaja Kjær Kristensen, Ying Liu, Henrik Callesen, Leslie Foldager
Publikováno v:
Liu, Y, Pedersen, H S, Larsen, K E, Kristensen, K, Foldager, L, Callesen, H & Sørensen, M T 2019, ' Combined in vitro fertilization and culture (IVF/IVC) in mouse for reprotoxicity assessment of xenobiotic exposure ', Reproductive Toxicology, vol. 89, no. October, pp. 115-123 . https://doi.org/10.1016/j.reprotox.2019.07.006
Litter size and other conventional measures in rodents are common end-points in the assessment of xenobiotics for reprotoxic effects. However, since litter size may be normal despite reduced semen quality, we established and tested a mouse in vitro f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc7b0029afeb5bf38aab6c2749319d3
https://pure.au.dk/portal/da/publications/combined-in-vitro-fertilization-and-culture-ivfivc-in-mouse-for-reprotoxicity-assessment-of-xenobiotic-exposure(1d9b0217-c3e7-4006-833a-ed4d41c5b485).html
https://pure.au.dk/portal/da/publications/combined-in-vitro-fertilization-and-culture-ivfivc-in-mouse-for-reprotoxicity-assessment-of-xenobiotic-exposure(1d9b0217-c3e7-4006-833a-ed4d41c5b485).html
Publikováno v:
Li, R, Liu, Y, Pedersen, H S & Callesen, H 2018, ' Effect of cumulus cells and sperm concentration on fertilization and development of pig oocytes ', Reproduction in Domestic Animals, vol. 53, pp. 1009-1012 . https://doi.org/10.1111/rda.13184
In pigs, in vitro fertilization (IVF) is still hampered by low blastocyst rates, first of all due to a high rate of polyspermy. The many attempts made to reduce this problem have often compromised penetration and fertilization rates, not improving ov
Autor:
Haja N. Kadarmideen, Henrik Callesen, Poul Hyttel, Lotte Stroebech, Hanne Skovsgaard Pedersen, Gianluca Mazzoni
Publikováno v:
Pedersen, H S, Mazzoni, G, Strøbech, L, Kadarmideen, H N, Hyttel, P & Callesen, H 2017, ' Basic and practical aspects of pregnancy establishment in cattle ', Animal Reproduction, vol. 14, no. 3, pp. 581-588 . https://doi.org/10.21451/1984-3143-AR1001
Bovine embryos are increasingly produced using reproductive technologies, e.g. ovum pick-up (OPU), in vitro embryo production (IVP) and embryo transfer (ET). Such in vitro manipulated embryos are known to deviate in several aspects compared to in viv