Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hanne R. Hagland"'
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Background In vitro drug screening that is more translatable to the in vivo tumor environment can reduce both time and cost of cancer drug development. Here we address some of the shortcomings in screening and show how treatment with 5‐flu
Externí odkaz:
https://doaj.org/article/bfc85fff93b440fda293eb1b3e1ab301
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Most in vitro cancer cell experiments have been performed using 2D models. However, 3D spheroid cultures are increasingly favored for being more representative of in vivo tumor conditions. To overcome the translational challenges
Externí odkaz:
https://doaj.org/article/47445122c8994eeb9ab62454994fb187
Autor:
Tian Carey, Abdelnour Alhourani, Ruiyuan Tian, Shayan Seyedin, Adrees Arbab, Jack Maughan, Lidija Šiller, Dominik Horvath, Adam Kelly, Harneet Kaur, Eoin Caffrey, Jong M. Kim, Hanne R. Hagland, Jonathan N. Coleman
Publikováno v:
npj 2D Materials and Applications, Vol 6, Iss 1, Pp 1-11 (2022)
Abstract The scalable production of two-dimensional (2D) materials is needed to accelerate their adoption to industry. In this work, we present a low-cost in-line and enclosed process of exfoliation based on high-shear mixing to create aqueous disper
Externí odkaz:
https://doaj.org/article/c0452deacd7e4440afcdc455a284bb97
Autor:
Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonl
Externí odkaz:
https://doaj.org/article/6d775d6752384370af9c1a1651d89e30
Publikováno v:
Translational Oncology, Vol 12, Iss 12, Pp 1583-1588 (2019)
INTRODUCTION: EMAST is a poorly understood form of microsatellite instability (MSI) in colorectal cancer (CRC) for which loss of MSH3 has been proposed as the underlying mechanism, based on experimental studies. We aimed to evaluate whether MSH3 loss
Externí odkaz:
https://doaj.org/article/4c422d1e12764fdf9b4e333845421992
Autor:
Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f8759eeba33b427bb6ebebb86ad5e97e
Autor:
Einar Gudlaugsson, Dordi Lea, Kjetil Søreide, Martin M. Watson, Hanne R. Hagland, Ivar Skaland
Publikováno v:
Cancer Immunology, Immunotherapy
Introduction Microsatellite instability (MSI) predict response to anti-PD1 immunotherapy in colorectal cancer (CRC). CRCs with MSI have higher infiltration of immune cells related to a better survival. Elevated Microsatellite Alterations at Tetranucl
Autor:
Martin M. Watson, Kjetil Søreide, Arezo Kanani, Hartwig Kørner, Dordi Lea, Ramesh B. Khajavi, Hanne R. Hagland, Jon Arne Søreide
Publikováno v:
Annals of Surgical Oncology. 27:1058-1067
Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a poorly investigated form of microsatellite instability (MSI) in colorectal cancer (CRC). The aim of this study was to investigate the clinicopathological features of EMAST
Graphene-based drug carriers provide a promising addition to current cancer drug 8 delivery options. Increased accessibility of high-quality graphene made by plasma- enhanced chemical vapor deposition (PE-CVD) makes it an attractive material to re-vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::423cf682d3c08540bda882755c4105f6
https://doi.org/10.26434/chemrxiv.14731695.v1
https://doi.org/10.26434/chemrxiv.14731695.v1
Autor:
Gro V. Røsland, Kjetil Søreide, Tia R. Tidwell, Ansooya Avinash Bokil, Abdelnour H. Alhourani, Karl Johan Tronstad, Hanne R. Hagland
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonly used to