Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hanne L. Ziegler"'
Autor:
Hanne L. Ziegler, Christian A. Olsen, Anders S. Kristensen, Matthias Witt, Jerzy W. Jaroszewski, Angelo Bella, Henrik Franzyk, Kristian Strømgaard, Sidsel Frølund
Publikováno v:
Journal of Medicinal Chemistry. 53:7441-7451
An array of analogues of the wasp toxin philanthotoxin-433, in which the asymmetric polyamine moiety was exchanged for spermine and the headgroup replaced with a variety of structurally diverse moieties, was prepared using parallel solid-phase synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13794b17e7959b273a72fcfb9e3fe1e9
https://doi.org/10.1021/jm100886h
https://doi.org/10.1021/jm100886h
Autor:
Javad Asili, Maja Lambert, Hanne L Ziegler, Jerzy W. Jaroszewski, Ismaiel S Ibrahimi, Matthias Witt, Majid Sairafianpour, Dan Staerk, Gholamreza Asghari
Publikováno v:
Journal of Natural Products. 67:631-637
Six labdanes (1-6) and four isopimaranes (7-10), including three new natural products (7, 9, and 10), were isolated from Platycladus orientalis, and their structures determined using 1D and 2D NMR methods, ion-cyclotron resonance HRMS, and optical ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7a9dde58c6901f6c95bb2634631411
https://doi.org/10.1021/np034033e
https://doi.org/10.1021/np034033e
Autor:
Mehrnoush Tabatabai, Henry Hägerstrand, Hanne L. Ziegler, Henrik Franzyk, Mahboubeh D Tehrani, Majid Sairafianpour, Karim Bagherzadeh, Dan Staerk, Jerzy W. Jaroszewski
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:119-127
The natural triterpene betulinic acid and its analogues (betulinic aldehyde, lupeol, betulin, methyl betulinate and betulinic acid amide) caused concentration-dependent alterations of erythrocyte membrane shape towards stomatocytes or echinocytes acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce93dd6464444d8389f50bade0c2c4e
https://doi.org/10.1016/j.bmc.2003.10.010
https://doi.org/10.1016/j.bmc.2003.10.010
Autor:
Dan Stærk, and Archibald A. Sittie, Hanne L. Ziegler, Jette Christensen, Jerzy W. Jaroszewski, Carl Erik Olsen
Publikováno v:
Journal of Natural Products. 65:1764-1768
Three novel triterpenes, (11R,20R)-11,20-dihydroxy-24-dammaren-3-one (1), (17S,20R,24R)-17,25-dihydroxy-20,24-epoxy-14(18)-malabaricen-3-one (2), and (17R,20S,24R)-17,25-dihydroxy-20,24-epoxy-14(18)-malabaricen-3-one (3), were isolated from leaves of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f565f2d6be9e4570bd27cbf76406b0f1
https://doi.org/10.1021/np0201826
https://doi.org/10.1021/np0201826
Autor:
Dan Staerk, Archibald Sittie, Thomas Jensen, Jerzy W. Jaroszewski, Henry Hägerstrand, Jette Christensen, Carl Erik Olsen, Trine Staalsø, Patrick Ekpe, Hanne L. Ziegler
Publikováno v:
Planta Medica. 68:547-549
Dehydroabietinol isolated from Hyptis suaveolens (L.) Poit. was found to inhibit growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). However, eryt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e35f5872f48db760deb2670ddb3ee5
https://doi.org/10.1055/s-2002-32548
https://doi.org/10.1055/s-2002-32548
Autor:
Hanne L. Ziegler, Christian A. Olsen, Hanne Mørck Nielsen, Niels Frimodt-Møller, Jerzy W. Jaroszewski, Henrik Franzyk
Publikováno v:
Chembiochem : a European journal of chemical biology. 11(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f432770133855df2586bef402bccd8f4
https://pubmed.ncbi.nlm.nih.gov/20503219
https://pubmed.ncbi.nlm.nih.gov/20503219
Autor:
Hassanata Mk, Hanne L. Ziegler, Guissou I. Pierre, T. R. Guiguemdé, O.G. Nacoulma, Carl Erik Olsen, Søren Brøgger Christensen, Traoré-Coulibaly M
Publikováno v:
Natural product research. 23(12)
A bioactivity guided fractionation of roots of Canthium multiflorum led to the isolation of the new ursenoic acid derivative 19alpha-hydroxy-3-oxo-ursa-1,12-dien-28-oic acid (1), which showed antiplasmodial effect without inducing change of the shape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc9f9d384cffea1298f77913e8aad62
https://pubmed.ncbi.nlm.nih.gov/19662575
https://pubmed.ncbi.nlm.nih.gov/19662575
Autor:
Jerzy W. Jaroszewski, Dan Staerk, Hanne L. Ziegler, Kennett Sprogøe, Søren Boe Holm-Møller, Thomas Jensen
Publikováno v:
Journal of natural products. 71(4)
Despite recent demonstration of the power of HPLC-PDA-MS-SPE-NMR (high-performance liquid chromatography-photodiode-array detection-mass spectrometry-solid-phase extraction-nuclear magnetic resonance) in structure determination of natural products di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37debf412b3aa4ab05326f369b2d5ec
https://pubmed.ncbi.nlm.nih.gov/18290629
https://pubmed.ncbi.nlm.nih.gov/18290629
Autor:
Camilla Foged, Christian A. Olsen, Jerzy W. Jaroszewski, Henrik Franzyk, Hanne L. Ziegler, Gitte Bonke, Line Vedel
Publikováno v:
Chembiochem : a European journal of chemical biology. 8(15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7eb0dee7d0576f7c2b02d68ca3f3fa
https://pubmed.ncbi.nlm.nih.gov/17854020
https://pubmed.ncbi.nlm.nih.gov/17854020
Loading of erythrocyte membrane with pentacyclic triterpenes inhibits Plasmodium falciparum invasion
Publikováno v:
Planta medica. 72(7)
Lupeol and betulinic acid inhibit the proliferation of Plasmodium falciparum parasites by inhibition of the invasion of merozoites into erythrocytes. This conclusion is based on experiments employing parasite cultures synchronized by magnetic cell so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff84ceabdd62aa0a13763eac0cc0cd21
https://pubmed.ncbi.nlm.nih.gov/16732511
https://pubmed.ncbi.nlm.nih.gov/16732511