Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hanne Klonowski"'
Publikováno v:
Pancreas. 31:156-167
Objective: The cytokines platelet-derived growth factor (PDGF) and transforming growth factor (TGF)-β1 are major factors influencing the transformation from the quiescent to the activated phenotype of pancreatic stellate cells (PSC), a process invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce3ea7023375e268fa78fa23f6b9213
https://doi.org/10.1097/01.mpa.0000168222.05591.a0
https://doi.org/10.1097/01.mpa.0000168222.05591.a0
Autor:
Roland Reinehr, Ulrich Warskulat, Reinhard Lüthen, Dieter Häussinger, Richard Fischer, Hanne Klonowski-Stumpe
Publikováno v:
Pancreas. 27:67-74
Introduction: Proliferation and matrix synthesis of activated pancreatic stellate cells (PSCs) participate in the development of chronic pancreatitis. Besides other substances, endpthelin-1 (ET-1) may influence the activation process of PSCs. Until n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0beb42b67cb3cc565eb62ab6886857
https://doi.org/10.1097/00006676-200307000-00010
https://doi.org/10.1097/00006676-200307000-00010
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 283:G819-G826
Proliferation and matrix synthesis by activated pancreatic stellate cells (PSC) participate in the development of chronic pancreatitis. Apoptosis of PSC may terminate this process but has not yet been studied in this particular cell type and was the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee01e2aead7010c186a6faedeee1f553
https://doi.org/10.1152/ajpgi.00073.2002
https://doi.org/10.1152/ajpgi.00073.2002
Publikováno v:
Pancreas. 24:53-62
Aims The effect of different modes of thiol depletion on pancreatic exocrine secretory function and potential mechanisms of interference with the secretory process in pancreatic acinar cells were investigated. Methodology After incubation with three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1246c9fe16f08dbce09f86ea64a436
https://doi.org/10.1097/00006676-200201000-00008
https://doi.org/10.1097/00006676-200201000-00008
Autor:
Bing Han, C. Niederau, Dieter Häussinger, Naohiro Sata, Hanne Klonowski-Stumpe, Reinhard Lüthen
Publikováno v:
Pancreas. 19:76-82
Little is known as yet about the role of apoptosis in pancreatic damage. This study evaluated the effects of supraphysiologic concentrations of the cholecystokinin (CCK) analog, cerulein, which causes cell damage in vitro and acute pancreatitis in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30eb09835a8e62ff00177e01f3e51404
https://doi.org/10.1097/00006676-199907000-00012
https://doi.org/10.1097/00006676-199907000-00012
Publikováno v:
Peptides. 19:291-299
The present study evaluates long-term effects of the CCK-agonist caerulein and the CCK-A antagonist loxiglumide in obese and lean Zucker rats. Caerulein and loxiglumide altered food intake neither in obese nor in lean rats. By as yet unknown mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe8cb1ecbef601919d8706eb40060c
https://doi.org/10.1016/s0196-9781(97)00261-1
https://doi.org/10.1016/s0196-9781(97)00261-1
Autor:
Dieter Häussinger, Naohiro Sata, Hanne Klonowski-Stumpe, Reinhard Lüthen, Bing Han, Claus Niederau
Publikováno v:
Pancreas. 16:96-101
Activation of trypsinogen is thought to trigger the autodigestive process in acute pancreatitis. The lysosomal enzyme cathepsin B was suggested to cause the activation of trypsinogen because it is known that cathepsin B is able to activate trypsinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3da239966c12d408af8058f4224a56
https://doi.org/10.1097/00006676-199801000-00015
https://doi.org/10.1097/00006676-199801000-00015
Publikováno v:
Suizo. 21:96-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f12ade3f0d701e4d2d427407759fd7e
https://doi.org/10.2958/suizo.21.96
https://doi.org/10.2958/suizo.21.96
Publikováno v:
Regulatory Peptides. 70:97-104
Obese Zucker rats are less sensitive to the satiety effect of CCK than lean litter mates. The present studies further characterised this CCK resistance. Subcutaneous injection of the CCK agonist caerulein dose-dependently decreased food intake in Zuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e4339e2c1f70147c60152cb9c3947c
https://doi.org/10.1016/s0167-0115(97)00014-1
https://doi.org/10.1016/s0167-0115(97)00014-1
Autor:
M. Grolik, Dieter Häussinger, C. Niederau, Hanne Klonowski-Stumpe, R. Schreiber, H. U. Schulz
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 272:G1489-G1498
The present study evaluates the effect of free radicals generated by xanthine oxidase-catalyzed oxidation of hypoxanthine on cellular function of isolated rat pancreatic acinar cells. The results show that a rapid and sustained increase in intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f70c6d2d38e216e4b67e88740630fe6
https://doi.org/10.1152/ajpgi.1997.272.6.g1489
https://doi.org/10.1152/ajpgi.1997.272.6.g1489