Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hanne Kinnunen"'
Autor:
Bown, Hanne Kinnunen, Bonn, Catherine, Yohe, Stefan, Yadav, Daniela Bumbaca, Patapoff, Thomas W., Daugherty, Ann, Mrsny, Randall J.
Publikováno v:
In Journal of Controlled Release 10 March 2018 273:13-20
Autor:
Ann L. Daugherty, Stefan T. Yohe, Daniela Bumbaca Yadav, Hanne Kinnunen Bown, Randall J. Mrsny, Catherine Bonn, Thomas W. Patapoff
Publikováno v:
Bown, H K, Bonn, C, Yohe, S T, Yadav, D B, Patapoff, T W, Daugherty, A L & Mrsny, R J 2018, ' In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies ', Journal of Controlled Release, vol. 273, pp. 13-20 . https://doi.org/10.1016/j.jconrel.2018.01.015
Monoclonal antibodies (mAbs), which are now more frequently administered by subcutaneous (SC) injection rather than intravenously, have become a tremendously successful drug format across a wide range of therapeutic areas. Preclinical evaluations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255ef842da5c5b4dc55cb9b9d55e8f86
https://pubmed.ncbi.nlm.nih.gov/29355621
https://pubmed.ncbi.nlm.nih.gov/29355621
Publikováno v:
AAPS PharmSciTech, 2014, Vol.15(4), pp.898-909 [Peer Reviewed Journal]
The effect of milled and micronized lactose fines on the fluidization and in vitro aerosolization properties of dry powder inhaler (DPI) formulations was investigated, and the suitability of static and dynamic methods for characterizing general powde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0e0eabd1485bb43be21d5693cbed6d
https://doi.org/10.1208/s12249-014-0119-6
https://doi.org/10.1208/s12249-014-0119-6
Publikováno v:
International journal of pharmaceutics, 2015, Vol.478(1), pp.53-59 [Peer Reviewed Journal]
The aim of the study was to investigate how the fine particle content of lactose carriers prepared with different types of lactose fines regulates dry powder inhaler (DPI) formulation performance of a cohesive batch of micronised budesonide. Budesoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6776f0f2eabb2d076051a7e75e8a1cac
Publikováno v:
Biomacromolecules. 7:1604-1609
Enzymatic oxidation of two phenolic compounds [syringic acid (3,5-dimethoxy-4-hydroxybenzoic acid) and 2,6-dimethylphenol] was studied. The products of laccase- and laccase-mediator-catalyzed oxidation reactions were monitored by matrix-assisted lase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae64fee01db931efe8ee5123536d5e2
https://doi.org/10.1021/bm060038p
https://doi.org/10.1021/bm060038p
Publikováno v:
AAPS PharmSciTech, 2014, Vol.15(4), pp.1009-1020 [Peer Reviewed Journal]
The study aimed to establish a function-based relationship between the physical and bulk properties of pre-blended mixtures of fine and coarse lactose grades with the in vitro performance of an adhesive active pharmaceutical ingredient (API). Differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fcaccd3000140ba33840b09a682397
Autor:
Randall J. Mrsny, Hanne Kinnunen
Publikováno v:
Journal of controlled release, 2014, Vol.182, pp.22-32 [Peer Reviewed Journal]
Subcutaneous (SC) injection is currently the most common route of self-administering biopharmaceuticals such as proteins and peptides. While pharmaceutical scientists have acquired great skill in identifying formulations for these proteins and peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45580cf2c473346f3a9e5cf826bafcca
http://dro.dur.ac.uk/13548/1/13548.pdf
http://dro.dur.ac.uk/13548/1/13548.pdf