Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hanne I Kristensen"'
Publikováno v:
University of Copenhagen
SummaryRecombinant human FVIIa (rFVIIa) was inactivated by coupling Phe-Phe-Arg-CO- (FFR) covalently to the active site of the enzyme. To test the chemically-modified human protein for potential antigenicity prior to clinical trial an immune-tolerant
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 15:515-520
Objective: To study whether locally administered recombinant inactivated human coagulation factor VIIa (FFR-rFVIIa) would reduce the thrombus formation and improve patency in an experimental venous thrombosis model without inducing systematic changes
Publikováno v:
Thrombosis and Haemostasis. 70:448-453
SummaryThe anticoagulant activities of Tissue Factor Pathway Inhibitor (TFPI), heparin and hirudin were compared in intrinsic (APTT) and extrinsic (PT) activated clotting assays. In contrast to the thrombin inhibitor hirudin, heparin was 10 fold more
Publikováno v:
Thrombosis and Haemostasis. 68:310-314
SummaryBoth the HEPTEST® and amidolytic anti factor Xa assays are currently being used for heparin activity detection in plasma from patients receiving standard heparin or low molecular weight heparin (LMWH). In this study we have investigated the i