Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hanne H. Henriksen"'
Autor:
Pär I. Johansson, Martin Vigstedt, Nicola S. Curry, Ross Davenport, Nicole P. Juffermans, Simon J. Stanworth, Marc Maegele, Christine Gaarder, Karim Brohi, Jakob Stensballe, Hanne H. Henriksen, for the Targeted Action for Curing Trauma-Induced Coagulopathy (TACTIC) Collaborators
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 32, Iss 1, Pp 1-11 (2024)
Abstract Background Trauma induced coagulopathy remains to be an important cause of high transfusion requirements and mortality and shock induced endotheliopathy (SHINE) has been implicated. Methods European multicenter observational study of adult t
Externí odkaz:
https://doaj.org/article/6f8526acc1e54a36ae8c1241ebaab0d0
Autor:
Pär I. Johansson, Hanne H. Henriksen, Sigurður T. Karvelsson, Óttar Rolfsson, Martin Schønemann-Lund, Morten H. Bestle, Sarah McGarrity
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Sepsis is a major cause of death worldwide, with a mortality rate that has remained stubbornly high. The current gold standard of risk stratifying sepsis patients provides limited mechanistic insight for therapeutic targeting. An improved ab
Externí odkaz:
https://doaj.org/article/738699080381430d9b45ae0de27a6d7f
Autor:
Nathan Weinstein, Jørn Carlsen, Sebastian Schulz, Timothy Stapleton, Hanne H. Henriksen, Evelyn Travnik, Pär Ingemar Johansson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionPulmonary hypertension (PH) is a pathological condition that affects approximately 1% of the population. The prognosis for many patients is poor, even after treatment. Our knowledge about the pathophysiological mechanisms that cause or ar
Externí odkaz:
https://doaj.org/article/71358bd7fd7d484d8ce5c3602042ac68
Autor:
Hanne H. Henriksen, Igor Marín de Mas, Helena Herand, Joseph Krocker, Charles E. Wade, Pär I. Johansson
Publikováno v:
Matrix Biology Plus, Vol 15, Iss , Pp 100115- (2022)
Purpose: Endotheliopathy of trauma (EoT), as defined by circulating levels of syndecan-1 ≥ 40 ng/mL, has been reported to be associated with significantly increased transfusion requirements and a doubled 30-day mortality. Increased shedding of the
Externí odkaz:
https://doaj.org/article/bc9e607d6fdf4fef99148f2f6536f929
Autor:
Hanne H. Henriksen, Igor Marín de Mas, Lars K. Nielsen, Joseph Krocker, Jakob Stensballe, Sigurður T. Karvelsson, Niels H. Secher, Óttar Rolfsson, Charles E. Wade, Pär I. Johansson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2257 (2023)
In trauma patients, shock-induced endotheliopathy (SHINE) is associated with a poor prognosis. We have previously identified four metabolic phenotypes in a small cohort of trauma patients (N = 20) and displayed the intracellular metabolic profile of
Externí odkaz:
https://doaj.org/article/f54990fe50e240ebb44f0d7a0ed15e8c
Autor:
Joseph D. Krocker, Kyung Hyun Lee, Hanne H. Henriksen, Yao-Wei Willa Wang, Erwin M. Schoof, Sigurdur T. Karvelsson, Óttar Rolfsson, Pär I. Johansson, Claudia Pedroza, Charles E. Wade
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6213 (2022)
Background: The endotheliopathy of trauma (EoT) is associated with increased mortality following injury. Herein, we describe the plasma proteome related to EoT in order to provide insight into the role of the endothelium within the systemic response
Externí odkaz:
https://doaj.org/article/35a2115bcb4649e6a2bad66d2e89e3c6
Autor:
Adrián López García de Lomana, Arnar Ingi Vilhjálmsson, Sarah McGarrity, Rósa Sigurðardóttir, Ósk Anuforo, Alexía Rós Viktorsdóttir, Aris Kotronoulas, Andreas Bergmann, Leifur Franzson, Haraldur Halldórsson, Hanne H. Henriksen, Charles E. Wade, Pär Ingemar Johansson, Óttar Rolfsson
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3162 (2022)
Disruption to endothelial cell homeostasis results in an extensive variety of human pathologies that are particularly relevant to major trauma. Circulating catecholamines, such as adrenaline and noradrenaline, activate endothelial adrenergic receptor
Externí odkaz:
https://doaj.org/article/cab676367f2749a5891e196438cbe300
Autor:
Sarah McGarrity, Ósk Anuforo, Haraldur Halldórsson, Andreas Bergmann, Skarphéðinn Halldórsson, Sirus Palsson, Hanne H. Henriksen, Pär Ingemar Johansson, Óttar Rolfsson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ. Here, we describe the con
Externí odkaz:
https://doaj.org/article/3346a06d5da14fb4a956f403770503f3
Autor:
Martin Vigstedt, Kjersti Baksaas-Aasen, Hanne H. Henriksen, Marc Maegele, Simon Stanworth, Nicole P. Juffermans, Knut M. Kolstadbråten, Pål A. Naess, Karim Brohi, Christine Gaarder, Jakob Stensballe, Pär I. Johansson
Publikováno v:
Scandinavian journal of clinical and laboratory investigation, 82(6), 508-512. Informa Healthcare
Severely injured trauma patients are often coagulopathic and early hemostatic resuscitation is essential. Previous studies have revealed linear relationships between thrombelastography (TEG®) five- and ten-min amplitudes (A5 and A10), and maximum am
Autor:
Martin, Vigstedt, Kjersti, Baksaas-Aasen, Hanne H, Henriksen, Marc, Maegele, Simon, Stanworth, Nicole P, Juffermans, Knut M, Kolstadbråten, Pål A, Naess, Karim, Brohi, Christine, Gaarder, Jakob, Stensballe, Pär I, Johansson
Publikováno v:
Scandinavian journal of clinical and laboratory investigation. 82(6)
Severely injured trauma patients are often coagulopathic and early hemostatic resuscitation is essential. Previous studies have revealed linear relationships between thrombelastography (TEG