Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Hanne F Harbo"'
Autor:
Keith E Kennedy, Nicole Kerlero de Rosbo, Antonio Uccelli, Maria Cellerino, Federico Ivaldi, Paola Contini, Raffaele De Palma, Hanne F Harbo, Tone Berge, Steffan D Bos, Einar A Høgestøl, Synne Brune-Ingebretsen, Sigrid A de Rodez Benavent, Friedemann Paul, Alexander U Brandt, Priscilla Bäcker-Koduah, Janina Behrens, Joseph Kuchling, Susanna Asseyer, Michael Scheel, Claudia Chien, Hanna Zimmermann, Seyedamirhosein Motamedi, Josef Kauer-Bonin, Julio Saez-Rodriguez, Melanie Rinas, Leonidas G Alexopoulos, Magi Andorra, Sara Llufriu, Albert Saiz, Yolanda Blanco, Eloy Martinez-Heras, Elisabeth Solana, Irene Pulido-Valdeolivas, Elena H Martinez-Lapiscina, Jordi Garcia-Ojalvo, Pablo Villoslada
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1010980 (2024)
Complex diseases such as Multiple Sclerosis (MS) cover a wide range of biological scales, from genes and proteins to cells and tissues, up to the full organism. In fact, any phenotype for an organism is dictated by the interplay among these scales. W
Externí odkaz:
https://doaj.org/article/c5917d61aa834152b3fb2018484da2fd
Autor:
Brooke Rhead, Ina S Brorson, Tone Berge, Cameron Adams, Hong Quach, Stine Marit Moen, Pål Berg-Hansen, Elisabeth Gulowsen Celius, Dipen P Sangurdekar, Paola G Bronson, Rodney A Lea, Sean Burnard, Vicki E Maltby, Rodney J Scott, Jeannette Lechner-Scott, Hanne F Harbo, Steffan D Bos, Lisa F Barcellos
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206511 (2018)
DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important gene pathways involved i
Externí odkaz:
https://doaj.org/article/f7193d155a0b49f58deed8a0dedea550
Autor:
Gro O Nygaard, Elisabeth G Celius, Sigrid A de Rodez Benavent, Piotr Sowa, Marte W Gustavsen, Anders M Fjell, Nils I Landrø, Kristine B Walhovd, Hanne F Harbo
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135974 (2015)
New treatment options may make "no evidence of disease activity" (NEDA: no relapses or disability progression and no new/enlarging MRI lesions, as opposed to "evidence of disease activity" (EDA) with at least one of the former), an achievable goal in
Externí odkaz:
https://doaj.org/article/9fbdfbe3a5824ec4bbbdd6719f81d293
Autor:
Ingvild S Leikfoss, Pankaj K Keshari, Marte W Gustavsen, Anja Bjølgerud, Ina S Brorson, Elisabeth G Celius, Anne Spurkland, Steffan D Bos, Hanne F Harbo, Tone Berge
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132957 (2015)
For multiple sclerosis, genome wide association studies and follow up studies have identified susceptibility single nucleotide polymorphisms located in or near CLEC16A at chromosome 16p13.13, encompassing among others CIITA, DEXI and SOCS1 in additio
Externí odkaz:
https://doaj.org/article/b1c79ed03ee340ca94fdc9ecf0b623c8
Autor:
Steffan D Bos, Christian M Page, Bettina K Andreassen, Emon Elboudwarej, Marte W Gustavsen, Farren Briggs, Hong Quach, Ingvild S Leikfoss, Anja Bjølgerud, Tone Berge, Hanne F Harbo, Lisa F Barcellos
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117403 (2015)
Determine whether MS-specific DNA methylation profiles can be identified in whole blood or purified immune cells from untreated MS patients.Whole blood, CD4+ and CD8+ T cell DNA from 16 female, treatment naïve MS patients and 14 matched controls was
Externí odkaz:
https://doaj.org/article/cef36fcc044540e299fe4568b13bea96
Autor:
Christian Magnus Page, Sergio E Baranzini, Bjørn-Helge Mevik, Steffan Daniel Bos, Hanne F Harbo, Bettina Kulle Andreassen
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139642 (2015)
Genotyping chips for rare and low-frequent variants have recently gained popularity with the introduction of exome chips, but the utility of these chips remains unclear. These chips were designed using exome sequencing data from mainly American-Europ
Externí odkaz:
https://doaj.org/article/866bd0af6eb94b89ba771bba630fed73
Autor:
Maurizio A Leone, Nadia Barizzone, Federica Esposito, Ausiliatrice Lucenti, Hanne F Harbo, An Goris, Ingrid Kockum, Annette Bang Oturai, Elisabeth Gulowsen Celius, Inger L Mero, Bénédicte Dubois, Tomas Olsson, Helle Bach Søndergaard, Daniele Cusi, Sara Lupoli, Bettina Kulle Andreassen, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium, Kjell-Morten Myhr, Franca R Guerini, PROGEMUS Group, PROGRESSO Group, Giancarlo Comi, Filippo Martinelli-Boneschi, Sandra D'Alfonso
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64408 (2013)
to explore the association between genetic markers and Oligoclonal Bands (OCB) in the Cerebro Spinal Fluid (CSF) of Italian Multiple Sclerosis patients.We genotyped 1115 Italian patients for HLA-DRB1*15 and HLA-A*02. In a subset of 925 patients we te
Externí odkaz:
https://doaj.org/article/44de3b4f33644da9a40dda1f2382e94e
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62237 (2013)
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative disease. It is thought to be mediated by CD4(+) Th1/Th17 cells. More recently, cells of the innate immune system such as dendritic cells (DCs) and natu
Externí odkaz:
https://doaj.org/article/e558fdc9554f45d0825cf24b52b910cb
Autor:
Inger-Lise Mero, Marte W Gustavsen, Hanne S Sæther, Siri T Flåm, Pål Berg-Hansen, Helle B Søndergaard, Poul Erik H Jensen, Tone Berge, Anja Bjølgerud, Aslaug Muggerud, Jan H Aarseth, International Multiple Sclerosis Genetics Consortium, Kjell-Morten Myhr, Elisabeth G Celius, Finn Sellebjerg, Jan Hillert, Lars Alfredsson, Tomas Olsson, Annette Bang Oturai, Ingrid Kockum, Benedicte A Lie, Bettina Kulle Andreassen, Hanne F Harbo
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58352 (2013)
The presence of oligoclonal bands (OCB) in cerebrospinal fluid (CSF) is a typical finding in multiple sclerosis (MS). We applied data from Norwegian, Swedish and Danish (i.e. Scandinavian) MS patients from a genome-wide association study (GWAS) to se
Externí odkaz:
https://doaj.org/article/c98d49fe062c440cbbc201493f684c34
Autor:
Angelina H Maniaol, Ahmed Elsais, Åslaug R Lorentzen, Jone F Owe, Marte K Viken, Hanne Sæther, Siri T Flåm, Geir Bråthen, Margitta T Kampman, Rune Midgard, Marte Christensen, Anna Rognerud, Emilia Kerty, Nils Erik Gilhus, Chantal M E Tallaksen, Benedicte A Lie, Hanne F Harbo
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36603 (2012)
BackgroundAcquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic risk factors of the human leu
Externí odkaz:
https://doaj.org/article/edbb9d2aa7fa423cb723be038e69af08