Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hanne Callewaert"'
Autor:
Caroline P. Martens, Pierre Van Mol, Joost Wauters, Els Wauters, Tanja Gangnus, Bernard Noppen, Hanne Callewaert, Jean H.M. Feyen, Laurens Liesenborghs, Elisabeth Heylen, Sander Jansen, Leydi Carolina Velásquez Pereira, Sirima Kraisin, Ipek Guler, Matthias M. Engelen, Anna Ockerman, Anke Van Herck, Robin Vos, Christophe Vandenbriele, Philippe Meersseman, Greet Hermans, Alexander Wilmer, Kimberly Martinod, Bjoern B. Burckhardt, Marc Vanhove, Marc Jacquemin, Peter Verhamme, Johan Neyts, Thomas Vanassche
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104195- (2022)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-converting enzyme 2 (ACE2) receptor, a critical component of the kallikrein-kinin system. Its dysregulation may lead to increased vascular perm
Externí odkaz:
https://doaj.org/article/e22bccf7e13b4f4e9d17aa33606b5009
Autor:
Cécile Mathieu, Hanne Callewaert, Lutgart Overbergh, Decio L. Eizirik, Molly Nelson-Holte, Fabrice Moore, Conny Gysemans
Publikováno v:
Diabetologia. 52:2374-2384
IFN-γ, together with other inflammatory cytokines such as IL-1β and TNF-α, contributes to beta cell death in type 1 diabetes. We analysed the role of the transcription factor interferon regulatory factor (IRF)-1, a downstream target of IFN-γ/sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e07af69ff28ff04aacaeffd9fc9f12
https://doi.org/10.1007/s00125-009-1514-5
https://doi.org/10.1007/s00125-009-1514-5
Publikováno v:
Biochemical Society Transactions. 36:328-333
IFNgamma (interferon gamma), a cytokine typically secreted by infiltrating immune cells in insulitis in Type 1 diabetes, is by itself not detrimental to beta-cells, but, together with other cytokines, such as IL-1beta (interleukin 1beta) and TNFalpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fb63991c6eb4eabc776568118f6ca7
https://doi.org/10.1042/bst0360328
https://doi.org/10.1042/bst0360328
Autor:
Conny Gysemans, Lutgart Overbergh, Laurence Ladrière, Wannes D'Hertog, Julianna Hagenbrock, Hanne Callewaert, Chantal Mathieu, Decio L. Eizirik
Publikováno v:
Diabetes. 56:2169-2173
OBJECTIVE—Exposure of β-cells to inflammatory cytokines leads to apoptotic cell death through the activation of gene networks under the control of specific transcription factors, such as interferon-γ–induced signal transducer and activator of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be6c46492d912dfc7f33bce848a0edd
https://doi.org/10.2337/db07-0052
https://doi.org/10.2337/db07-0052
Autor:
Decio L. Eizirik, Chantal Mathieu, Conny Gysemans, Roger Bouillon, Annapaula Giulietti, Leen Hulshagen, Hanne Callewaert, Alessandra K Cardozo
Publikováno v:
Endocrinology. 146:1956-1964
1,25-Dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)) is an immune modulator that prevents experimental autoimmune diseases. Receptors for 1,25-(OH)(2)D(3) are present in pancreatic beta-cells, the target of an autoimmune assault in nonobese diabetic (NOD) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a03e0f203ab4312dfc1f6961c441a1
https://doi.org/10.1210/en.2004-1322
https://doi.org/10.1210/en.2004-1322
Publikováno v:
Biochemical Society transactions. 36(Pt 3)
IFNgamma (interferon gamma), a cytokine typically secreted by infiltrating immune cells in insulitis in Type 1 diabetes, is by itself not detrimental to beta-cells, but, together with other cytokines, such as IL-1beta (interleukin 1beta) and TNFalpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36fdc770b82fdcae58dab3908ccd2bea
https://pubmed.ncbi.nlm.nih.gov/18481951
https://pubmed.ncbi.nlm.nih.gov/18481951
Autor:
Decio L. Eizirik, Markus Tiedge, Matthias Elsner, Alessandra K Cardozo, Conny Gysemans, Hanne Callewaert, Chantal Mathieu
Publikováno v:
Cell Transplantation, Vol 16 (2007)
Islet transplantation is a promising treatment in type 1 diabetes, but the need for chronic immunosuppression is a major hurdle to broad applicability. Ex vivo introduction of agents by lentiviral vectors—improving β-cell resistance against immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819b9ea265f075f960efda107e6d90f2
https://pubmed.ncbi.nlm.nih.gov/17708342
https://pubmed.ncbi.nlm.nih.gov/17708342
Autor:
Laurence Ladrière, Hanne Callewaert, Patrick Matthys, Conny Gysemans, David E. Levy, Chantal Mathieu, Daisy Flamez, Decio L. Eizirik, Joanne Rasschaert
Publikováno v:
Diabetes. 54(8)
beta-cells under immune attack are destroyed by the aberrant activation of key intracellular signaling cascades. The aim of the present study was to evaluate the contribution of the signal transducer and activator of transcription (STAT)-1 pathway fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d9bb956099543ec1885920f5ca33b6
https://pubmed.ncbi.nlm.nih.gov/16046307
https://pubmed.ncbi.nlm.nih.gov/16046307