Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Hanne, Mørck Nielsen"'
Autor:
Mai Bay Stie, Cristiana Cunha, Zheng Huang, Jacob Judas Kain Kirkensgaard, Pernille Sønderby Tuelung, Feng Wan, Hanne Mørck Nielsen, Vito Foderà, Stine Rønholt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Native mucus is heterogeneous, displays high inter-individual variation and is prone to changes during harvesting and storage. To overcome the lack of reproducibility and availability of native mucus, commercially available purified mucins,
Externí odkaz:
https://doaj.org/article/1b157940f626489fa3f2bfd160346d22
Autor:
Janni Støvring Mortensen, Søren S.-R. Bohr, Lasse Skjoldborg Krog, Johan Peter Bøtker, Vaya Kapousidou, Lasse Saaby, Nikos S. Hatzakis, Hanne Mørck Nielsen, Duc Ninh Nguyen, Stine Rønholt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The integrity of the intestinal mucus barrier is crucial for human health, as it serves as the body's first line of defense against pathogens. However, postnatal development of the mucus barrier and interactions between maturity and its abil
Externí odkaz:
https://doaj.org/article/51a5f4f8091449cca95c1878c5b87547
Autor:
Anne Weiss, Emilie Delavenne, Carina Matias, Heimo Lagler, Daniel Simon, Ping Li, Jon U. Hansen, Teresa Pires dosSantos, Bimal Jana, Petra Priemel, Christine Bangert, Martin Bauer, Sabine Eberl, Alina Nussbaumer‐Pröll, Zoe Anne Österreicher, Peter Matzneller, Tamara Quint, Maria Weber, Hanne Mørck Nielsen, Thomas Rades, Helle Krogh Johansen, Henrik Westh, Wooseong Kim, Eleftherios Mylonakis, Christian Friis, Luca Guardabassi, John Pace, Carina Vingsbo Lundberg, Fatima M'Zali, Pascal Butty, Nikolaj Sørensen, Henrik Bjørn Nielsen, Rasmus Toft‐Kehler, Emma Guttman‐Yassky, Georg Stingl, Markus Zeitlinger, Morten Sommer
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract Background In patients with atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions and is hypothesized to be linked to disease severity and progression. Treatments that reduce S. aureus colonization without significantly
Externí odkaz:
https://doaj.org/article/c12af968bd3a4c4badc928f617fc3d24
Autor:
Miriam E. van Gent, Tom van Baaren, Sylvia N. Kłodzińska, Muhanad Ali, Natasja Dolezal, Bjorn R. van Doodewaerd, Erik Bos, Amy M. de Waal, Roman I. Koning, Jan Wouter Drijfhout, Hanne Mørck Nielsen, Peter H. Nibbering
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 429 (2023)
Chronic wound infections colonized by bacteria are becoming more difficult to treat with current antibiotics due to the development of antimicrobial resistance (AMR) as well as biofilm and persister cell formation. Synthetic antibacterial and antibio
Externí odkaz:
https://doaj.org/article/b518551780ec46efb7e3e99e2e77ddab
Autor:
Stine Harloff-Helleberg, Lies A. L. Fliervoet, Mathias Fanø, Mechthild Schmitt, Maxim Antopolski, Arto Urtti, Hanne Mørck Nielsen
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 532-541 (2019)
Oral drug delivery is an attractive noninvasive alternative to injectables. However, oral delivery of biopharmaceuticals is highly challenging due to low stability during transit in the gastrointestinal tract (GIT), resulting in low systemic bioavail
Externí odkaz:
https://doaj.org/article/de17d752cdc448ca8dd3d8f9834ce964
Publikováno v:
Drug Delivery and Translational Research. 13:1456-1469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822accea21d3014352a166d8665aeca1
https://doi.org/10.1007/s13346-023-01309-8
https://doi.org/10.1007/s13346-023-01309-8
Publikováno v:
Materials & Design, Vol 201, Iss , Pp 109486- (2021)
Additive manufacturing based on direct laser writing two-photon polymerization facilitates the fabrication of microstructures with full 3D design freedom. Here, this fabrication technique is exploited for engineering scaffolds accurately mimicking th
Externí odkaz:
https://doaj.org/article/457570e4c8c2488b962b85cde033c665
Publikováno v:
Tollemeto, M, Huang, Z, Christensen, J B, Mørck Nielsen, H & Harloff-Helleberg, S 2023, ' Mucoadhesive Dendrons Conjugated to Mesoporous Silica Nanoparticles as a Drug Delivery Approach for Orally Administered Biopharmaceuticals ', ACS Applied Materials and Interfaces, vol. 15, no. 7, pp. 8798–8810 . https://doi.org/10.1021/acsami.2c16502
Biological drugs are increasingly important for patients and industry due to their application in the treatment of common and potentially life-threatening diseases such as diabetes, cancer, and obesity. While most marketed biopharmaceuticals today ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4b6c8366fa19c0f097ccc925c0329f
https://doi.org/10.1021/acsami.2c16502
https://doi.org/10.1021/acsami.2c16502
Autor:
Xin Zhou, Anders Wilgaard Sinkjær, Min Zhang, Henrik Dahl Pinholt, Hanne Mørck Nielsen, Nikos S. Hatzakis, Marco van de Weert, Vito Foderà
Publikováno v:
The Journal of Physical Chemistry Letters. 14:912-919
Amyloid aggregation is associated with many diseases and may also occur in therapeutic protein formulations. Addition of co-solutes is a key strategy to modulate the stability of proteins in pharmaceutical formulations and select inhibitors for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d60825827aa615f8013a41bbc9751d
https://doi.org/10.1021/acs.jpclett.2c03400
https://doi.org/10.1021/acs.jpclett.2c03400
Publikováno v:
Cell‐Penetrating Peptides. :329-354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a6f66fafb5ecd21b41972898ae56d7
https://doi.org/10.1002/9783527835997.ch18
https://doi.org/10.1002/9783527835997.ch18