Multivariate statistical process control (MSPC) using Raman spectroscopy for in-line culture cell monitoring considering time-varying batches synchronized with correlation optimized warping (COW)

Autor: Liu, Ya-Juan, André, Silvère, Saint Cristau, Lydia, Lagresle, Sylvain, Hannas, Zahia, Calvosa, Éric, Devos, Olivier, Duponchel, Ludovic

Publikováno v: In Analytica Chimica Acta 1 February 2017 952:9-17

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Developing global regression models for metabolite concentration prediction regardless of cell line.

Autor: André S; LASIR CNRS UMR 8516, Université de Lille, Sciences et Technologies, 59655, Villeneuve d'Ascq Cedex, France., Lagresle S; Merial, Lyon, France., Da Sliva A; Transgene, Illkirch-Graffenstaden Cedex, France., Heimendinger P; Transgene, Illkirch-Graffenstaden Cedex, France., Hannas Z; Merial, Lyon, France., Calvosa É; Sanofi Pasteur, Marcy-l'Étoile, France., Duponchel L; LASIR CNRS UMR 8516, Université de Lille, Sciences et Technologies, 59655, Villeneuve d'Ascq Cedex, France.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2017 Nov; Vol. 114 (11), pp. 2550-2559. Date of Electronic Publication: 2017 Aug 29.