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Presynaptic hyperexcitability reversed by positive allosteric modulation of a GABABR epilepsy variant.

Autor: Minere M; Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK., Mortensen M; Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK., Dorovykh V; Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK., Warnes G; Blizard Institute, Barts and The London School of Medicine and Dentistry, London, E1 2AT, UK., Nizetic D; Blizard Institute, Barts and The London School of Medicine and Dentistry, London, E1 2AT, UK., Smart TG; Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK., Hannan SB; Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK.; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2024 Jul 19. Date of Electronic Publication: 2024 Jul 19.