Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hannah Y.‐Y. Lee"'
Publikováno v:
Meat science. 143
High pressure processing (HPP) of pre-rigor longissimus thoracis (strip loin) from prime and bull animals substantially decreased the shear force and improved consumer eating attributes of the final meat product. The improved tenderness in both prime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac85972b1cef960bcf3da471ba3e638
https://pubmed.ncbi.nlm.nih.gov/29751219
https://pubmed.ncbi.nlm.nih.gov/29751219
Autor:
R. Grant Pearson, Roy Bickerstaffe, Hannah Y.-Y. Lee, Susan L. Mason, James D. Morton, Stephanie Smithson
Publikováno v:
Meat science. 133
Strip loins from different grades of cattle were subjected to two levels of high pressure processing (HPP) within 1h of slaughter at a commercial meat processing plant and chilled for 1day before freezing. The physical and eating quality characterist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc35511411aad347f2ae30150d7324d7
https://pubmed.ncbi.nlm.nih.gov/28649047
https://pubmed.ncbi.nlm.nih.gov/28649047
Publikováno v:
Food Chemistry. 117:318-325
Various physicochemical and biochemical properties were compared between raw mature and immature chinook salmon (Oncorhynchus tshawytscha) roe. The pH, osmolality and moisture content were lower for mature salmon roe but egg size, viscosity, protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d3ba7011a4799be6ab8ae7c1f2950f
https://doi.org/10.1016/j.foodchem.2009.04.009
https://doi.org/10.1016/j.foodchem.2009.04.009
Autor:
Andrew D. Abell, Matthew A. Jones, James M. Coxon, James D. Morton, Steven G. Aitken, Stephen B. McNabb, Hannah Y.‐Y. Lee, Janna M. Mehrtens, Nathan A. Alexander, Blair G. Stuart, Axel T. Neffe, Roy Bickerstaffe
Publikováno v:
Angewandte Chemie. 121:1483-1486
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6cad966680c7b4b07e02add87f75eb9
https://doi.org/10.1002/ange.200805014
https://doi.org/10.1002/ange.200805014
Autor:
Joshua D McDermott, James M. Coxon, Matthew A. Jones, Janna M. Mehrtens, Andrew D. Abell, Lucinda J. G. Robertson, James D. Morton, Roy Bickerstaffe, Hannah Y.-Y. Lee
Publikováno v:
Clinical & Experimental Ophthalmology. 36:852-860
The aim of this study is to evaluate the therapeutic potential of a newly synthesized calpain inhibitor, CAT0059, using a naturally occurring in vivo sheep cataract model.The selectivity of CAT0059 was investigated by an in vitro protease assay. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bc056b859c2c6710d0e6f31915fb01
https://doi.org/10.1111/j.1442-9071.2009.01925.x
https://doi.org/10.1111/j.1442-9071.2009.01925.x
Autor:
Roy Bickerstaffe, Hannah Y.-Y. Lee, Matthew A. Jones, Lucinda J. G. Robertson, Andrew D. Abell, James D. Morton, Josh D. McDermott, James M. Coxon
Publikováno v:
Investigative ophthalmologyvisual science. 54(1)
We used sheep with an autosomal dominant gene for cortical cataract as an animal model to evaluate novel macrocyclic calpain inhibitors with potential for the medical treatment of human cataract.The macrocyclic aldehyde, CAT811, identified previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362fc7858a48126742118a69704ec86b
https://pubmed.ncbi.nlm.nih.gov/23211821
https://pubmed.ncbi.nlm.nih.gov/23211821
Autor:
Axel T. Neffe, Blair G. Stuart, James D. Morton, Janna M. Mehrtens, James M. Coxon, Andrew D. Abell, Roy Bickerstaffe, Hannah Y.-Y. Lee, Matthew A. Jones, Steven G. Aitken, Stephen B. McNabb, Nathan A. Alexander
Publikováno v:
Angewandte Chemie (International ed. in English). 48(8)
The design and elaboration of a series of macrocyclic templates that exhibit a propensity to adopt a beta-strand-like peptide-backbone conformation led to potent and selective inhibitors of calpain 2. Macrocycle 1 retarded calcium-induced opacificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ee0f1debd297feb2cc9b2dfa873f0e
https://pubmed.ncbi.nlm.nih.gov/19145612
https://pubmed.ncbi.nlm.nih.gov/19145612
Autor:
Lucinda J. G. Robertson, Roy Bickerstaffe, Hannah Y.-Y. Lee, James D. Morton, Julie Sanderson
Publikováno v:
Veterinary ophthalmology. 11(6)
Objective To investigate biochemical changes accompanying Ca2+-induced lens opacification and the possible role of calpain activation in opacification within an ovine lens culture system. Methods Sheep lenses were cultured in minimal media. Lens opac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07dce013e440f7931ae41df4e5ba7c3
https://pubmed.ncbi.nlm.nih.gov/19046274
https://pubmed.ncbi.nlm.nih.gov/19046274
Autor:
Janna M. Mehrtens, James D. Morton, Andrew D. Abell, James M. Coxon, Steven G. Aitken, Matthew A. Jones, Stephen B. McNabb, Axel T. Neffe, Roy Bickerstaffe, Shigeru Miyamoto, Hannah Y.-Y. Lee, Lucinda J. G. Robertson, Karl Gately, Jacqueline M. Wood
Publikováno v:
Bioorganicmedicinal chemistry. 16(14)
A series of N-heterocyclic dipeptide aldehydes 4-13 have been synthesised and evaluated as inhibitors of ovine calpain 1 (o-CAPN1) and ovine calpain 2 (o-CAPN2). 5-Formyl-pyrrole 9 (IC(50) values of 290 and 25nM against o-CAPN1 and o-CAPN2, respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa376ff734f80ecf730ba621a4b27ea2
https://pubmed.ncbi.nlm.nih.gov/18571418
https://pubmed.ncbi.nlm.nih.gov/18571418
Autor:
James M. Coxon, Stephen B. McNabb, Hannah Y.-Y. Lee, Thomas P. Cain, Axel T. Neffe, Blair G. Stuart, James D. Morton, Richard J. Payne, Andrew D. Abell, David Pearson, Matthew A. Jones, Steven G. Aitken
Publikováno v:
Journal of medicinal chemistry. 50(12)
The photoswitchable N-terminal diazo and triazene-dipeptide aldehydes 8a−d, 10a,b, and 17a,b present predominantly as the (E)-isomer, which purportedly binds deep in the S3 pocket of calpain. All compounds are potent inhibitors of m-calpain, with 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70ca77e1a4f5c9335432bd6c44d4c12
https://pubmed.ncbi.nlm.nih.gov/17497840
https://pubmed.ncbi.nlm.nih.gov/17497840