Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Hannah Y, Wen"'
Autor:
Higinio Dopeso, Andrea M. Gazzo, Fatemeh Derakhshan, David N. Brown, Pier Selenica, Sahar Jalali, Arnaud Da Cruz Paula, Antonio Marra, Edaise M. da Silva, Thais Basili, Laxmi Gusain, Lorraine Colon-Cartagena, Shirin Issa Bhaloo, Hunter Green, Chad Vanderbilt, Steffi Oesterreich, Anne Grabenstetter, M. Gabriela Kuba, Dara Ross, Dilip Giri, Hannah Y. Wen, Hong Zhang, Edi Brogi, Britta Weigelt, Fresia Pareja, Jorge S. Reis-Filho
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract CDH1 (E-cadherin) bi-allelic inactivation is the hallmark alteration of breast invasive lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however, lack CDH1 genetic/epigenetic inactivation, and their genetic
Externí odkaz:
https://doaj.org/article/2bcd7e3ff5014c2e98a7bf5bd912578b
Autor:
Reith R. Sarkar, MD, Jessica A. Lavery, PhD, Zhigang Zhang, PhD, Boris A. Mueller, MD, MPH, Melissa Zinovoy, MD, John J. Cuaron, MD, Beryl McCormick, MD, Atif J. Khan, MD, Simon N. Powell, MD, PhD, Hannah Y. Wen, MD, Lior Z. Braunstein, MD
Publikováno v:
Advances in Radiation Oncology, Vol 9, Iss 7, Pp 101508- (2024)
Purpose: Intravascular tumor emboli in axillary soft tissue (ITE) is a rare pathologic finding in breast cancer and is associated with higher axillary nodal disease burden. The independent prognostic and predictive value of this entity is unknown, as
Externí odkaz:
https://doaj.org/article/ba3cee14873a4485a21bbdee90c68823
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Rare subtypes of triple-negative breast cancers (TNBC) are a heterogenous group of tumors, comprising 5–10% of all TNBCs. Despite accounting for an absolute number of cases in aggregate approaching that of other less common, but well studi
Externí odkaz:
https://doaj.org/article/4e4b7df9a81044c7a074d3e2ffbe07ea
Autor:
Anne Grabenstetter, Edi Brogi, Hong Zhang, Pedram Razavi, Jorge S. Reis-Filho, Kimberly J. VanZee, Larry Norton, Hannah Y. Wen
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-4 (2022)
Abstract Breast adenoid cystic carcinoma (AdCC) is a rare subtype of triple negative breast cancer. Two morphologic variants are described, namely classic AdCC (C-AdCC) and solid basaloid (SB-AdCC). Recent studies have shown that the SB-AdCC variant
Externí odkaz:
https://doaj.org/article/98a28fe893f7487cb3e93d9bf03a21b2
Autor:
Emanuela Ferraro, Jasmeet Singh, Sujata Patil, Pedram Razavi, Shanu Modi, Sarat Chandarlapaty, Andrea V. Barrio, Rachna Malani, Ingo K. Mellinghoff, Adrienne Boire, Hannah Y. Wen, Edi Brogi, Andrew D. Seidman, Larry Norton, Mark E. Robson, Chau T. Dang
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract The addition of pertuzumab (P) to trastuzumab (H) and neoadjuvant chemotherapy (NAC) has decreased the risk of distant recurrence in early stage HER2-positive breast cancer. The incidence of brain metastases (BM) in patients who achieved pat
Externí odkaz:
https://doaj.org/article/5efc975ad4074b27a5124e022f559502
Autor:
Willard Wong, Edi Brogi, Jorge S. Reis-Filho, George Plitas, Mark Robson, Larry Norton, Monica Morrow, Hannah Y. Wen
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Metaplastic breast carcinoma (MpBC) is a rare special histologic subtype of breast carcinoma characterized by the presence of squamous and/or mesenchymal differentiation. Most MpBCs are of triple-negative phenotype and neoadjuvant chemothera
Externí odkaz:
https://doaj.org/article/dfb94e25ff8d460f8dd36265079a5e88
Autor:
Lea A. Moukarzel, Lorenzo Ferrando, Arnaud Da Cruz Paula, David N. Brown, Felipe C. Geyer, Fresia Pareja, Salvatore Piscuoglio, Anastasios D. Papanastasiou, Nicola Fusco, Caterina Marchiò, Nadeem R. Abu‐Rustum, Rajmohan Murali, Edi Brogi, Hannah Y. Wen, Larry Norton, Robert A. Soslow, Anne Vincent‐Salomon, Jorge S. Reis‐Filho, Britta Weigelt
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 1024-1039 (2021)
Metaplastic breast carcinoma (MBC) and uterine carcinosarcoma (UCS) are rare aggressive cancers, characterized by an admixture of adenocarcinoma and areas displaying mesenchymal/sarcomatoid differentiation. We sought to define whether MBCs and UCSs h
Externí odkaz:
https://doaj.org/article/d43d7492291245088deab363a8092b63
Autor:
Edaise M. da Silva, Pier Selenica, Mahsa Vahdatinia, Fresia Pareja, Arnaud Da Cruz Paula, Lorenzo Ferrando, Andrea M. Gazzo, Higinio Dopeso, Dara S. Ross, Ariya Bakhteri, Nadeem Riaz, Sarat Chandarlapaty, Pedram Razavi, Larry Norton, Hannah Y. Wen, Edi Brogi, Britta Weigelt, Hong Zhang, Jorge S. Reis-Filho
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Metaplastic breast cancers (MBCs) are characterized by complex genomes, which seem to vary according to their histologic subtype. TERT promoter hotspot mutations and gene amplification are rare in common forms of breast cancer, but present i
Externí odkaz:
https://doaj.org/article/f132c81e88b1476593e2db603427ca32
Autor:
Timothy M D'Alfonso, Fresia Pareja, Arnaud Da Cruz Paula, Mahsa Vahdatinia, Andrea Gazzo, Lorenzo Ferrando, Edaise M da Silva, Esther Cheng, Lisa Sclafani, Sarat Chandarlapaty, Hong Zhang, Syed A Hoda, Hannah Y Wen, Edi Brogi, Britta Weigelt, Jorge S Reis‐Filho
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 2, Pp 113-120 (2021)
Abstract Juvenile papillomatosis (JP) of the breast is a rare benign mass‐forming lesion occurring in young women, which is histologically characterized by a constellation of proliferative changes and large cysts, giving it the gross appearance of
Externí odkaz:
https://doaj.org/article/f30c2cca903d4d859d3f9b547aded646
Autor:
Hatice U. Osmanbeyoglu, Fumiko Shimizu, Angela Rynne-Vidal, Direna Alonso-Curbelo, Hsuan-An Chen, Hannah Y. Wen, Tsz-Lun Yeung, Petar Jelinic, Pedram Razavi, Scott W. Lowe, Samuel C. Mok, Gabriela Chiosis, Douglas A. Levine, Christina S. Leslie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Epigenomic data on chromatin accessibility and transcription factor occupancy can reveal enhancer landscapes in cancer. Here, the authors develop a computational strategy called PSIONIC (patient-specific inference of networks informed by chromatin) t
Externí odkaz:
https://doaj.org/article/ae04ca5ec19545a0b464c26486748931