Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hannah W. Clayton"'
Autor:
Karrie D. Dudek, Christian J. Stoeckert, Jean-Philippe Cartailler, Leah Potter Case, Hannah W. Clayton, Anna B. Osipovich, Guoqiang Gu, Emily Greenfest-Allen, Eun-Young Choi, Mark A. Magnuson, Austin Chapman, Elisabetta Manduchi
Publikováno v:
Development. 148
To gain a deeper understanding of pancreatic β-cell development, we used iterative weighted gene correlation network analysis to calculate a gene co-expression network (GCN) from 11 temporally and genetically defined murine cell populations. The GCN
Autor:
Anna B, Osipovich, Karrie D, Dudek, Emily, Greenfest-Allen, Jean-Philippe, Cartailler, Elisabetta, Manduchi, Leah, Potter Case, Eunyoung, Choi, Austin G, Chapman, Hannah W, Clayton, Guoqiang, Gu, Christian J, Stoeckert, Mark A, Magnuson
Publikováno v:
Development
To gain a deeper understanding of pancreatic β-cell development, we used iterative weighted gene correlation network analysis to calculate a gene co-expression network (GCN) from 11 temporally and genetically defined murine cell populations. The GCN
Autor:
Hannah W. Clayton, James O'Connor, Jean-Philippe Cartailler, Matthew T. Dickerson, Prasanna K. Dadi, Mark A. Magnuson, Anna B. Osipovich, David A. Jacobson, Jennifer S. Stancill
Publikováno v:
Diabetes. 66:2175-2187
We used mice lacking Abcc8 , a key component of the β-cell K ATP -channel, to analyze the effects of a sustained elevation in the intracellular Ca 2+ concentration ([Ca 2+ ] i ) on β-cell identity and gene expression. Lineage tracing analysis revea
Autor:
Mark A. Magnuson, Carolyn M. Shanks, Jennifer S. Stancill, Guoqiang Gu, Judsen Schneider, Weiping Yuan, Christian J. Stoeckert, Pedro G. Vianna, Hannah W. Clayton, Anna B. Osipovich, Elisabetta Manduchi
Publikováno v:
Cell Reports. 17:2028-2041
Summary Using a transgenic mouse model to express MafA , Pdx1, and Neurog3 (3TF) in a pancreatic acinar cell- and doxycycline-dependent manner, we discovered that the outcome of transcription factor-mediated acinar to β-like cellular reprogramming i
Autor:
Jennifer S, Stancill, Jean-Philippe, Cartailler, Hannah W, Clayton, James T, O'Connor, Matthew T, Dickerson, Prasanna K, Dadi, Anna B, Osipovich, David A, Jacobson, Mark A, Magnuson
Publikováno v:
Diabetes
We used mice lacking Abcc8, a key component of the β-cell KATP-channel, to analyze the effects of a sustained elevation in the intracellular Ca2+ concentration ([Ca2+]i) on β-cell identity and gene expression. Lineage tracing analysis revealed the