Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hannah U. C. Brass"'
Autor:
Lena Berning, Thomas Lenz, Ann Kathrin Bergmann, Gereon Poschmann, Hannah U. C. Brass, David Schlütermann, Annabelle Friedrich, María José Mendiburo, Céline David, Seda Akgün, Jörg Pietruszka, Kai Stühler, Björn Stork
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported to affect cancer cells but not non-maligna
Externí odkaz:
https://doaj.org/article/7ecfe60b57124e5b8a217be3a9ae7907
Autor:
Samer S. Habash, Hannah U. C. Brass, Andreas S. Klein, David P. Klebl, Tim Moritz Weber, Thomas Classen, Jörg Pietruszka, Florian M. W. Grundler, A. Sylvia S. Schleker
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Bacterial metabolites represent an invaluable source of bioactive molecules which can be used as such or serve as chemical frameworks for developing new antimicrobial compounds for various applications including crop protection against pathogens. Pro
Externí odkaz:
https://doaj.org/article/40dd2a94a1814263a0a6071cd09ba29e
Autor:
Lena Berning, David Schlütermann, Annabelle Friedrich, Niklas Berleth, Yadong Sun, Wenxian Wu, María José Mendiburo, Jana Deitersen, Hannah U. C. Brass, Margaretha A. Skowron, Michèle J. Hoffmann, Günter Niegisch, Jörg Pietruszka, Björn Stork
Publikováno v:
Molecules, Vol 26, Iss 5, p 1294 (2021)
Cisplatin-based treatment is the standard of care therapy for urothelial carcinomas. However, complex cisplatin resistance mechanisms limit the success of this approach. Both apoptosis and autophagy have been shown to contribute to this resistance. P
Externí odkaz:
https://doaj.org/article/14a3d2f23be8408f9da609e017ad8f1a
Autor:
Anna Joëlle Ruff, Ulrich Schwaneberg, Mehdi D. Davari, Jarno G. Sikkens, Hannah U. C. Brass, Stefanie Brands, Andreas Sebastian Klein, Jörg Pietruszka
Publikováno v:
Catalysis Science & Technology. 11:2805-2815
Prodigiosin ligase PigC catalyses the final condensation step in the prodigiosin biosynthesis of Serratia marcescens, in which two pyrrolic precursor molecules are fused linearly to form tripyrrolic red prodiginines. Prodiginine compounds attracted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ba94f81dfb273cd9fb5078ec0f7040
https://doi.org/10.1039/d0cy02297g
https://doi.org/10.1039/d0cy02297g
Autor:
Stefanie Brands, Andreas Sebastian Klein, Anna Joëlle Ruff, Hannah U. C. Brass, Jörg Pietruszka, Ulrich Schwaneberg
Publikováno v:
Chemical communications 56(61), 8631-8634 (2020). doi:10.1039/D0CC02181D
A colourimetric high-throughput screening system was established for directed evolution of prodigiosin ligase PigC. The two-step system consists of a colony prescreening test and a subsequent photometric 96-well plate assay. Screening PigC epPCR libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012c6bc42ca8f04f4aeeaaefe2adfe51
https://doi.org/10.1039/d0cc02181d
https://doi.org/10.1039/d0cc02181d
Autor:
null Carl Brehl, null Hannah U. C. Brass, null Clara Lüchtrath, null Lukas Böckmann, null Nina Ihling, null Thomas Classen, null Jörg Pietruszka, null Jochen Büchs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399924c5e937ce7b24414f1f6ed18ec5
https://doi.org/10.1002/btpr.3245/v2/response1
https://doi.org/10.1002/btpr.3245/v2/response1
Autor:
Carl Brehl, Hannah U. C. Brass, Clara Lüchtrath, Lukas Böckmann, Nina Ihling, Thomas Classen, Jörg Pietruszka, Jochen Büchs
Publikováno v:
Biotechnology progress 38(3), e3245 (2022). doi:10.1002/btpr.3245
Biotechnology progress e3245 (2022). doi:10.1002/btpr.3245
Published by Wiley, Malden, MA
Published by Wiley, Malden, MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b716a65116f94461f39e5007b2a72cd3
Autor:
Stefanie Brands, Anna Joëlle Ruff, Ulrich Schwaneberg, Hannah U. C. Brass, Jarno G. Sikkens, Andreas Sebastian Klein, Mehdi D. Davari, Jörg Pietruszka
Publikováno v:
Chemical communications 57(21), 2681-2684 (2021). doi:10.1039/D0CC08226K
Semi-rational redesign of the substrate binding pocket and access tunnels of prodigiosin ligase PigC enhanced the catalytic efficiency in the synthesis of pyrrolic anti-cancer agents more than 45 times. A molecular understanding was gained on residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b952fe0f46c3c05393c8c145573311dc
https://hdl.handle.net/2128/29752
https://hdl.handle.net/2128/29752
Autor:
Jörg Pietruszka, Margaretha A. Skowron, Günter Niegisch, Yadong Sun, Lena Berning, Jana Deitersen, Niklas Berleth, Annabelle Friedrich, Wenxian Wu, Michèle J. Hoffmann, Björn Stork, Hannah U. C. Brass, David Schlütermann, María José Mendiburo
Publikováno v:
Molecules
Molecules 26(5), 1294-(2021). doi:10.3390/molecules26051294
Volume 26
Issue 5
Molecules, Vol 26, Iss 1294, p 1294 (2021)
Molecules 26(5), 1294-(2021). doi:10.3390/molecules26051294
Volume 26
Issue 5
Molecules, Vol 26, Iss 1294, p 1294 (2021)
Cisplatin-based treatment is the standard of care therapy for urothelial carcinomas. However, complex cisplatin resistance mechanisms limit the success of this approach. Both apoptosis and autophagy have been shown to contribute to this resistance. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06d5eda58a37d38fe2c1d52cad65d80
https://pubmed.ncbi.nlm.nih.gov/33673611
https://pubmed.ncbi.nlm.nih.gov/33673611
Autor:
Jörg Pietruszka, Thomas Classen, David Paul Klebl, Hannah U. C. Brass, Florian M. W. Grundler, Andreas Sebastian Klein, A. Sylvia S. Schleker, Samer S. Habash, Tim Moritz Weber
Publikováno v:
Frontiers in Functional Plant Ecology 11, 579807 (2020). doi:10.3389/fpls.2020.579807
Frontiers in Plant Science, Vol 11 (2020)
Frontiers in Plant Science
Frontiers in Plant Science, Vol 11 (2020)
Frontiers in Plant Science
Bacterial metabolites represent an invaluable source of bioactive molecules which can be used as such or serve as chemical frameworks for developing new antimicrobial compounds for various applications including crop protection against pathogens. Pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d027aa1c115b2115ec7b0dae435082
https://doi.org/10.3389/fpls.2020.579807
https://doi.org/10.3389/fpls.2020.579807