Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hannah Thel"'
Autor:
Jeffrey W. Clark, Lauren Matlack, Sanya Arshad, Ryan B. Corcoran, Aparna Raj Parikh, Benjamin D. Greenbaum, Colin D. Weekes, Michael J. Raabe, Lorraine C. Drapek, Jon Dubois, Theodore S. Hong, David P. Ryan, David T. Ting, Lipika Goyal, Bronwen Foreman, Bruce J. Giantonio, Leilana Ly, Hannah Thel, Arnav Mehta, Lawrence S. Blaszkowsky, Nir Hacohen, Andrew X. Zhu, Jennifer Y. Wo, David Hoyos, Ryan D. Nipp, Emily E. Van Seventer, Jill N. Allen, Annamaria Szabolcs, Jessica A. Meurer, David J. Lieb, Beow Y. Yeap
Publikováno v:
Nature Cancer. 2:1124-1135
Overcoming intrinsic resistance to immune checkpoint blockade for microsatellite stable (MSS) colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) remains challenging. We conducted a single-arm, non-randomized, phase II trial (NCT03104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::991579e2e4f5b9b9fc7265f801fe62e1
https://doi.org/10.1038/s43018-021-00269-7
https://doi.org/10.1038/s43018-021-00269-7
Publikováno v:
Cancer Research. 83:979-979
Background: Pancreatic ductal adenocarcinoma (PDAC) demonstrates variable prognosis and response to first-line FOLFIRINOX therapy depending on molecular subtype; patients with classical tumors showed a greater response compared to basal-like tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98d0f8a6ebda9824d727d13651e944ca
https://doi.org/10.1158/1538-7445.am2023-979
https://doi.org/10.1158/1538-7445.am2023-979
Autor:
Beow Y. Yeap, Bronwen Foreman, David Hoyos, Nir Hacohen, Sanya Arshad, Jennifer Y. Wo, Lauren Matlack, Jon Dubois, Benjamin Greenbaum, Colin D. Weekes, David P. Ryan, David J. Lieb, Lawrence S. Blaszkowsky, Ryan D. Nipp, Arnav Mehta, Leilana Ly, Emily E. Van Seventer, Annamaria Szabolcs, Jill N. Allen, Jessica A. Meurer, Lorraine C. Drapek, Jeffrey W. Clark, Andrew X. Zhu, Ryan B. Corcoran, Lipika Goyal, Bruce J. Giantonio, Hannah Thel, Theodore S. Hong, David T. Ting, Aparna Raj Parikh
Immune checkpoint blockade has limited efficacy in microsatellite stable (MSS) colorectal (CRC) and pancreatic (PDAC) cancer. Preclinical models have demonstrated the use of radiation to activate the innate immune response and stimulate responsivenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e56b0a1948d63053def5275a1df4e7f
https://doi.org/10.21203/rs.3.rs-58489/v1
https://doi.org/10.21203/rs.3.rs-58489/v1
