Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hannah S. Tims"'
Publikováno v:
Journal of Molecular Biology. 411:430-448
Nucleosomes sterically occlude their wrapped DNA from interacting with many large protein complexes. How proteins gain access to nucleosomal DNA target sites in vivo is not known. Outer stretches of nucleosomal DNA spontaneously unwrap and rewrap wit
Publikováno v:
Nature structural & molecular biology
The packaging of eukaryotic DNA into chromatin sterically occludes polymerases, recombinases and repair enzymes. How chromatin structure changes to allow their actions is unknown. We constructed defined fluorescently labeled trinucleosome arrays, all
Autor:
Hannah S. Tims, Jonathan Widom
Publikováno v:
Methods. 41:296-303
Macromolecular assemblies and machines undergo large-scale conformational changes as essential features of their normal function. Modern stopped-flow instrumentation and biotechnology combine to provide a powerful tool for characterizing the rates an
Autor:
Hannah S. Tims, Virginia B. Pett, Tea Meulia, Tamutenda Chidawanyika, Robert A. Bouchard, Roger D. Klein
Publikováno v:
Plant science : an international journal of experimental plant biology.
Small heat shock proteins (sHsps) are molecular chaperones that protect cells from the effect of heat and other stresses. Some sHsps are also expressed at specific stages of development. In plants different classes of sHsps are expressed in the vario
Publikováno v:
Journal of molecular biology. 412(4)
Cooperativity in transcription factor (TF) binding is essential in eukaryotic gene regulation, and arises through diverse mechanisms. Here we focus on one mechanism, collaborative competition, which is of interest because it arises both automatically
Publikováno v:
The FASEB Journal. 23
Autor:
Hannah S. Tims, Katherine Ann Stencel
Publikováno v:
The FASEB Journal. 23