Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hannah R. Spaulding"'
Autor:
Swathy Krishna, Hannah R. Spaulding, James E. Koltes, John C. Quindry, Rudy J. Valentine, Joshua T. Selsby
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle wasting, wheelchair dependence, and eventual death due to cardiac and respiratory complications. In addition to muscle fragility, dystrophin deficiency also resu
Externí odkaz:
https://doaj.org/article/e24a80efa87547af8ced1ecc2e6fb343
Indices of Defective Autophagy in Whole Muscle and Lysosome Enriched Fractions From Aged D2-mdx Mice
Autor:
Swathy Krishna, Hannah R. Spaulding, Tiffany S. Quindry, Matthew B. Hudson, John C. Quindry, Joshua T. Selsby
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Duchenne muscular dystrophy (DMD) is a fatal, progressive muscle disease caused by the absence of functional dystrophin protein. Previous studies in mdx mice, a common DMD model, identified impaired autophagy with lysosomal insufficiency and impaired
Externí odkaz:
https://doaj.org/article/8dbd602249e14a72b3e5807d72283ba8
Autor:
Zhen Yan, Hannah R. Spaulding
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Extracellular superoxide dismutase (EcSOD) is the only extracellular scavenger of superoxide anion (O2.-) with unique binding capacity to cell surface and extracellular matrix through its heparin-binding domain. Enhanced EcSOD activity prevents oxida
Externí odkaz:
https://doaj.org/article/e40d9db3f3684c2a85ecd15eb88cd4fe
Publikováno v:
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Duchenne muscular dystrophy (DMD) is caused by the absence of functional dystrophin protein and results in progressive muscle wasting. Dystrophin deficiency leads to a host of dysfunctional cellular processes including impaired autophagy. Au
Externí odkaz:
https://doaj.org/article/cd26f90403c1472abea8ab55f08d7629
Autor:
Hannah R. Spaulding, Zhen Yan
Publikováno v:
Annu Rev Physiol
Noncommunicable diseases are chronic diseases that contribute to death worldwide, but these diseases can be prevented and mitigated with regular exercise. Exercise activates signaling molecules and the transcriptional network to promote physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef8c66528bbd4fb15e6015a33a8cbe8
https://doi.org/10.1146/annurev-physiol-060721-095517
https://doi.org/10.1146/annurev-physiol-060721-095517
Autor:
Ruofan Cao, David F. Kashatus, Eric M. Desjardins, Anna S. Nichenko, Jitendra Gautam, Matthew H. Brisendine, Huayu Shang, Hannah R. Spaulding, D. Grahame Hardie, Joshua C. Drake, Yuntian Guan, Horst Wallrabe, Mei Zhang, Maya V. Dorn, Aloka B. Bandara, Rebecca J. Wilson, Matthew J. Wolf, Michael Wong, Jennifer A. Kashatus, Gregory R. Steinberg, Kian Huang, Clint L. Miller, Simon A. Hawley, George J. Christ, Wenqing Shen, Poonam Sharma, Paul A. Chang, Zhen Yan, Ammasi Periasamy, Alexander S. Young, Rhianna C. Laker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Here, we present unequivocal evidence of physical association of AMPK holoenzymes with mitochondrial reticulum (mitoAMPK) across multiple mouse tissues with evidence of conservation in human skeletal muscle and heart. We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacd6cacaed2ee2763e46a56be4eb882
https://hdl.handle.net/10919/107452
https://hdl.handle.net/10919/107452
Indices of Defective Autophagy in Whole Muscle and Lysosome Enriched Fractions From Aged D2-mdx Mice
Autor:
Matthew B. Hudson, Swathy Krishna, Hannah R. Spaulding, Joshua T. Selsby, John C. Quindry, Tiffany S. Quindry
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Duchenne muscular dystrophy (DMD) is a fatal, progressive muscle disease caused by the absence of functional dystrophin protein. Previous studies in mdx mice, a common DMD model, identified impaired autophagy with lysosomal insufficiency and impaired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be22507acb836ce0b025870c22b489c6
http://europepmc.org/articles/PMC8299564
http://europepmc.org/articles/PMC8299564
Publikováno v:
J Appl Physiol (1985)
Progressive muscle injury and weakness are hallmarks of Duchenne muscular dystrophy. We showed previously that quercetin (Q) partially protected dystrophic limb muscles from disease-related injury. As quercetin activates PGC-1α through Sirtuin-1, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440b473f77f50dfe0ac6217558644f8f
https://doi.org/10.1152/japplphysiol.00162.2019
https://doi.org/10.1152/japplphysiol.00162.2019
Publikováno v:
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports
Duchenne muscular dystrophy (DMD) is caused by the absence of functional dystrophin protein and results in progressive muscle wasting. Dystrophin deficiency leads to a host of dysfunctional cellular processes including impaired autophagy. Autophagic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e674f317508bfc8f05926e0a458c3d
https://doaj.org/article/cd26f90403c1472abea8ab55f08d7629
https://doaj.org/article/cd26f90403c1472abea8ab55f08d7629
Autor:
Hannah R. Spaulding, Joshua T. Selsby
Publikováno v:
Medicine & Science in Sports & Exercise. 50:1723-1732
Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by a dystrophin protein deficiency. Dystrophin functions to stabilize and protect the muscle fiber during muscle contraction; thus, the absence of functional dystrophin protein leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c22c727fcc822fc4ca616e4ca71619f
https://doi.org/10.1249/mss.0000000000001639
https://doi.org/10.1249/mss.0000000000001639