Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hannah R. Ortiz"'
Autor:
Hannah R. Ortiz, Paola Cruz Flores, Julia Podgorski, Aaron Ramonett, Tasmia Ahmed, Nadine Hempel, Pascale G. Charest, Nathan A. Ellis, Paul R. Langlais, William R. Montfort, Karthikeyan Mythreye, Sanjay Kumar, Nam Y. Lee
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 53, Iss , Pp 101003- (2024)
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating with many ER-shaping protei
Externí odkaz:
https://doaj.org/article/274b38172af341548cf9d7362df38b4a
Autor:
Eun‐A. Kwak, Tasmia Ahmed, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18981-18987 (2023)
Abstract Background Tumor‐associated angiogenesis mediates the growth and metastasis of most solid cancers. Targeted therapies of the VEGF pathways can effectively block these processes but often fail to provide lasting benefits due to acquired res
Externí odkaz:
https://doaj.org/article/76d3ddb6cc2e43c1a453556387455958
Autor:
Eun-A Kwak, Christopher C. Pan, Aaron Ramonett, Sanjay Kumar, Paola Cruz-Flores, Tasmia Ahmed, Hannah R. Ortiz, Jeffrey J. Lochhead, Nathan A. Ellis, Ghassan Mouneimne, Teodora G. Georgieva, Yeon Sun Lee, Todd W. Vanderah, Tally Largent-Milnes, Peter J. Mohler, Thomas J. Hund, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Defective angiogenesis remains a high source of morbidity in multiple disorders. Here they show that βIV-spectrin, a membrane-associated cytoskeletal protein, is essential for regulation of endothelial tip cell populations and VEGF signaling during
Externí odkaz:
https://doaj.org/article/9b6fe5a83d2b46eeafef20d5197ddbd4
Autor:
Tasmia Ahmed, Aaron Ramonett, Eun-A Kwak, Sanjay Kumar, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Thomas J. Hund, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Molecular Biology of the Cell. 34
The first transcriptional pathway regulating βIV-spectrin expression, a key angiogenic regulator of sprouting angiogenesis, is identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24da983d824f6b3f1c065ce173b9f75
https://doi.org/10.1091/mbc.e23-02-0064
https://doi.org/10.1091/mbc.e23-02-0064
Autor:
Hannah R. Ortiz, Paola Cruz Flores, Aaron Ramonett, Tasmia Ahmed, Nathan A. Ellis, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
bioRxiv
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating with many ER-shaping protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6769303883027ba17f10d2843f896362
https://europepmc.org/articles/PMC10153279/
https://europepmc.org/articles/PMC10153279/
Autor:
Tasmia Ahmed, Paola Cruz Flores, Christopher C. Pan, Hannah R. Ortiz, Yeon S. Lee, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
The Journal of biological chemistry. 298(9)
Insulin signaling in blood vessels primarily functions to stimulate angiogenesis and maintain vascular homeostasis through the canonical PI3K and MAPK signaling pathways. However, angiogenesis is a complex process coordinated by multiple other signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e5dfeb9766e1aec69e123efb4e50c7
https://pubmed.ncbi.nlm.nih.gov/35872017
https://pubmed.ncbi.nlm.nih.gov/35872017
Autor:
Sanjay Kumar, Aaron Ramonett, Tasmia Ahmed, Eun-A Kwak, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
SUMMARYMitochondrial remodeling is a fundamental process underlying cellular respiration and metabolism. Here we report TAK1 as a direct regulator of mitochondrial fusion. TAK1 is activated by a variety of mitogenic factors, cytokines and environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d80639560f2afb3ff10dca035bce9d
https://doi.org/10.1101/2022.01.11.475884
https://doi.org/10.1101/2022.01.11.475884
Autor:
Tasmia Ahmed, Aaron Ramonett, Eun-A Kwak, Sanjay Kumar, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Journal of Biological Chemistry. 299:104044
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22e0439554e77a3889ed7986f64dc7e
https://doi.org/10.1016/j.jbc.2023.104044
https://doi.org/10.1016/j.jbc.2023.104044
Autor:
Eun-A, Kwak, Christopher C, Pan, Aaron, Ramonett, Sanjay, Kumar, Paola, Cruz-Flores, Tasmia, Ahmed, Hannah R, Ortiz, Jeffrey J, Lochhead, Nathan A, Ellis, Ghassan, Mouneimne, Teodora G, Georgieva, Yeon Sun, Lee, Todd W, Vanderah, Tally, Largent-Milnes, Peter J, Mohler, Thomas J, Hund, Paul R, Langlais, Karthikeyan, Mythreye, Nam Y, Lee
Publikováno v:
Nature communications. 13(1)
Defective angiogenesis underlies over 50 malignant, ischemic and inflammatory disorders yet long-term therapeutic applications inevitably fail, thus highlighting the need for greater understanding of the vast crosstalk and compensatory mechanisms. Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::314b5dcc4b77e5363e4ee8437448d580
https://pubmed.ncbi.nlm.nih.gov/35288568
https://pubmed.ncbi.nlm.nih.gov/35288568