Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hannah R. Manion"'
Publikováno v:
Biochemistry. 60:1947-1951
MqnD catalyzes the conversion of cyclic dehypoxanthine futalosine (6) to 5,8-dihydroxy-2-naphthoic acid (7) and an uncharacterized product. This study describes a chemoenzymatic synthesis of 6. This synthesis achieved a 2-fold yield enhancement by us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cb0ce753824de1e327bae5d852c6ac
https://doi.org/10.1021/acs.biochem.1c00257
https://doi.org/10.1021/acs.biochem.1c00257
Autor:
Bradley K Alexander, D. Cole Stevens, Adrian T. Keatinge-Clay, Hannah R. Manion, Drew T. Wagner
Publikováno v:
The Journal of antibiotics
Methyltransferases excised from trans -AT polyketide synthases operate on N -acetylcysteamine-bound substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d7f796f6665c6121cf690a8cbf1ed0
https://doi.org/10.1038/ja.2016.66
https://doi.org/10.1038/ja.2016.66
Autor:
Drew T. Wagner, Jia Zeng, Constance B. Bailey, Darren C. Gay, Fang Yuan, Hannah R. Manion, Adrian T. Keatinge-Clay
Publikováno v:
Structure (London, England : 1993). 25(7)
In an effort to uncover the structural motifs and biosynthetic logic of the relatively uncharacterized trans-acyltransferase polyketide synthases, we have begun the dissection of the enigmatic dehydrating bimodules common in these enzymatic assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6b217493c1a0de0c8e5d7ed4aa8302
https://pubmed.ncbi.nlm.nih.gov/28625788
https://pubmed.ncbi.nlm.nih.gov/28625788
Autor:
Hannah R. Manion, Richard E. Taylor, Jennifer S. Brodbelt, M. Rachel Mehaffey, Drew T. Wagner, Adrian T. Keatinge-Clay, D. Cole Stevens
C-methyltransferases (MTs) from modular polyketide synthase assembly lines are relatively rare and unexplored domains that are responsible for installing α-methyl groups into nascent polyketide backbones. The stage at which these synthase-embedded e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39d373bfd958ac290be87d32f0b10f4
https://europepmc.org/articles/PMC4948183/
https://europepmc.org/articles/PMC4948183/
