Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hannah Neiswender"'
Autor:
Hannah Neiswender, Frederick C. Baker, Rajalakshmi Veeranan-Karmegam, Phylicia Allen, Graydon B. Gonsalvez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
We recently identified the Drosophila ortholog of TTC1 (dTtc1) as an interacting partner of Egalitarian, an RNA adaptor of the Dynein motor. In order to better understand the function of this relatively uncharacterized protein, we depleted dTtc1 in t
Externí odkaz:
https://doaj.org/article/7e9f1ad1f0ce4c5986b0996c96d945aa
Publikováno v:
Dev Biol
Egalitarian (Egl) is an RNA adaptor for the Dynein motor and is thought to link numerous, perhaps hundreds, of mRNAs with Dynein. Dynein, in turn, is responsible for the transport and localization of these mRNAs. Studies have shown that efficient mRN
Autor:
Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez, Frederick C. Baker, Chandler H. Goldman, Saurav Misra
Publikováno v:
RNA Biol
The Dynein motor is responsible for the localization of numerous mRNAs within Drosophila oocytes and embryos. The RNA binding protein, Egalitarian (Egl), is thought to link these various RNA cargoes with Dynein. Although numerous studies have shown t
Publikováno v:
Development
Numerous motors of the Kinesin family contribute to plus-end directed microtubule transport. However, almost all transport towards the minus-end of microtubules involves Dynein. Understanding the mechanism by which Dynein transports this vast diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf3e59e8a0d4b7fc80e5fa9c42ff767
https://europepmc.org/articles/PMC8645207/
https://europepmc.org/articles/PMC8645207/
Autor:
Hannah Neiswender, Ellen K. LeMosy
A highly-conserved extracellular matrix protein, Tinagl1, modulates Wnt, integrin, TGF-β, and EGF-R signalingin vitro,but its significancein vivohas remained in doubt. To bypass possible genetic compensation by an ortholog encoded exclusively in mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9c60b409e40f46205a6b28e3855bc9
https://doi.org/10.1101/2020.06.05.136747
https://doi.org/10.1101/2020.06.05.136747
Publikováno v:
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 54(4)
ObjectiveTinagl1 has a weak genetic association with craniosynostosis, but its functions in cartilage and bone development are unknown. Knockdown of Tinagl1 in zebrafish embryos allowed an initial characterization of its potential effects on craniofa
Autor:
Tian Ming Gao, Ezekiel Carpenter-Hyland, Daehoon Lee, Wen Cheng Xiong, Xian-Ping Dong, Annie K.L. Ting, Chang-Hoon Kim, Lin Mei, Shi Wen Luo, Hannah Neiswender, Bin Zhang, Xiao-Ming Li
Publikováno v:
Nature Neuroscience. 11:262-268
Synapse formation requires proper interaction between pre- and postsynaptic cells. In anterograde signaling, neurons release factors to guide postsynaptic differentiation. However, less is known about how postsynaptic targets retrogradely regulate pr
Autor:
Hannah Neiswender, Ezekiel Carpenter-Hyland, Yanmei Tao, Tian Ming Gao, Cary Lai, Lin Mei, Wen Cheng Xiong, Yang Zhong Huang, Jiong Wu, Xiao-Ming Li, Ran Sook Woo, Janet L. Weber, Martin Gassmann, Xian-Ping Dong
Publikováno v:
Neuron. 54(4):599-610
SummaryNeuregulin-1 (NRG1), a regulator of neural development, has been shown to regulate neurotransmission at excitatory synapses. Although ErbB4, a key NRG1 receptor, is expressed in glutamic acid decarboxylase (GAD)-positive neurons, little is kno
Publikováno v:
Molecular and cellular biology. 28(9)
Wnt regulation of muscle development is thought to be mediated by the beta-catenin-TCF/LEF-dependent canonical pathway. Here we demonstrate that beta-catenin, not TCF/LEF, is required for muscle differentiation. We showed that beta-catenin interacts
Autor:
Zhe Han, Penny Roon, Mazen Fakhouri, Ellen K. LeMosy, Jacklyn D. Hall, Maggie Elalayli, Hannah Neiswender, Tambrea T. Ellison
Publikováno v:
Developmental Biology. (2):359-369
The innermost layer of the Drosophila eggshell, the vitelline membrane, provides structural support and positional information to the embryo. It is assembled in an incompletely understood manner from four major proteins to form a homogeneous, transpa