Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hannah M. Kirton"'
Autor:
Miriam E. Hurley, Shihab S. Shah, Thomas M. D. Sheard, Hannah M. Kirton, Derek S. Steele, Nikita Gamper, Izzy Jayasinghe
Publikováno v:
Cells, Vol 13, Iss 1, p 38 (2023)
Coordinated events of calcium (Ca2+) released from the endoplasmic reticulum (ER) are key second messengers in excitable cells. In pain-sensing dorsal root ganglion (DRG) neurons, these events can be observed as Ca2+ sparks, produced by a combination
Externí odkaz:
https://doaj.org/article/ed1be321deb1400ab073fea9567ebdb9
Autor:
Emma J. Steer, Zhaokang Yang, Moza M. Al-Owais, Hannah M. Kirton, Edward White, Derek S. Steele
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: While flecainide is now an accepted treatment for arrhythmias associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), its mechanism of action remains controversial. In studies on myocytes from CPVT mice,
Externí odkaz:
https://doaj.org/article/67857d3bbcf941a2ace61eb090bed825
Publikováno v:
Physiological Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract Purpose Current understanding of ventricular action potential adaptation to physiological stress is generally based on protocols using non‐physiological rates and conditions isolating rate effects from escalating adrenergic stimulation. To
Externí odkaz:
https://doaj.org/article/feb36c7c6a72465b92112db67e552706
Autor:
Eleftheria Pervolaraki, Nikita Gamper, Ruth Norman, Izzy Jayasinghe, Thomas M. D. Sheard, Shihab Shah, Miriam E. Hurley, Hannah M. Kirton, Zhaokang Yang, Derek S. Steele, Ed White
Nanometre-scale cellular information obtained through super-resolution microscopies are often unaccompanied by functional information, particularly transient and diffusible signals through which life is orchestrated in the nano-micrometre spatial sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69dfe26707e338fd4199b8fc7e989849
https://doi.org/10.1101/2020.09.29.319400
https://doi.org/10.1101/2020.09.29.319400
Autor:
Thomas M. D. Sheard, Nikita Gamper, Shihab Shah, Ed White, Eleftheria Pervolaraki, Derek S. Steele, Zhaokang Yang, Ruth Norman, Miriam E. Hurley, Izzy Jayasinghe, Hannah M. Kirton
Publikováno v:
Methods (San Diego, Calif.). 193
Nanometre-scale cellular information obtained through super-resolution microscopies are often unaccompanied by functional information, particularly transient and diffusible signals through which life is orchestrated in the nano-micrometre spatial sca
Autor:
Miriam E. Hurley, Izzy Jayasinghe, Derek S. Steele, Nikita Gamper, Hannah M. Kirton, Shihab Shah, Eleftheria Pervolaraki, Zhaokang Yang, Edward D. White, Ruth Norman, Thomas M. D. Sheard
Publikováno v:
Biophysical Journal. 118:172a
Autor:
Hannah M. Kirton
Publikováno v:
Physiology News. :18-19
Autor:
Hannah M. Kirton
Publikováno v:
Physiology News. :36-37
Publikováno v:
Biophysical Journal. 110(3)
In adult rat ventricular myocytes (ARVMs), local Ca2+-release from the Golgi apparatus (GA) was stimulated by a low level of isoproterenol (10 nM) in combination with (1) phosphodiesterase-3 inhibitor (milrinone, 30 µM), (2) phosphodiesterase-4 inhi
Publikováno v:
Biophysical Journal. 114:140a