Výsledky vyhledávání - "Hannah M. Jahn"

Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia

Autor: Alexei Verkhratsky, Hannah M. Jahn, Carmen V. Kasakow, Andreas G. Helfer, Anja Scheller, Hans H. Maurer, Julian A. Michely, Frank Kirchhoff

Publikováno v: Scientific Reports
Jahn, H M, Kasakow, C V, Helfer, A, Michely, J, Verkhratsky, A, Maurer, H H, Scheller, A & Kirchhoff, F 2018, ' Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia ', Scientific Reports, vol. 8, no. 1, 5913 . https://doi.org/10.1038/s41598-018-24085-9
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Inducible DNA recombination of floxed alleles in vivo by liver metabolites of tamoxifen (TAM) is an important tool to study gene functions. Here, we describe protocols for optimal DNA recombination in astrocytes, based on the GLAST-CreERT2/loxP syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3511c710ce48661171a414bc4ede9e6
https://doi.org/10.1038/s41598-018-24085-9

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Critical periods regulating the circuit integration of adult-born hippocampal neurons

Autor: Hannah M. Jahn, Matteo Bergami

Publikováno v: Cell and Tissue Research

The dentate gyrus (DG) in the adult brain maintains the capability to generate new granule neurons life-long. Neural stem cell-derived new-born neurons are emerging for playing key functions in the way information is processed in the DG and then conv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88febda28220f9abf3bd009f6063b3f3
https://link.springer.com/article/10.1007/s00441-017-2677-x

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The inhibitory input to mouse cerebellar Purkinje cells is reciprocally modulated by Bergmann glial P2Y1 and AMPA receptor signaling

Autor: Ramona, Rudolph, Hannah M, Jahn, Raphael, Courjaret, Nanette, Messemer, Frank, Kirchhoff, Joachim W, Deitmer

Publikováno v: Glia. 64(7)

Synaptic transmission has been shown to be modulated by glial functions, but the modes of specific glial action may vary in different neural circuits. We have tested the hypothesis, if Bergmann GLIA (BG) are involved in shaping neuronal communication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2fc9b78c6ca14a49a713bf63932311c3
https://pubmed.ncbi.nlm.nih.gov/27144942

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Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

Publikováno v: Neuron

Oligodendrocytes make myelin and support axons metabolically with lactate. However, it is unknown how glucose utilization and glycolysis are adapted to the different axonal energy demands. Spiking axons release glutamate and oligodendrocytes express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399972c58c46da5a666244b577934266
https://www.zora.uzh.ch/id/eprint/127960/

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The E3-ubiquitin ligase TRIM2 regulates neuronal polarization

Autor: Peter Young, Eva C. Bunk, Anna-Lena Hillje, Eva M. Riegler, Jürgen A. Knoblich, Mohammad Khazaei, Hannah M. Jahn, Jens Christian Schwamborn

Publikováno v: Journal of Neurochemistry. 117:29-37

The establishment of a polarized morphology with a single axon and multiple dendrites is an essential step during neuronal differentiation. This cellular polarization is largely depending on changes in the dynamics of the neuronal cytoskeleton. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::225af708a32c8d11e2934cc71b4b89b7
https://doi.org/10.1111/j.1471-4159.2010.06971.x

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Genetic control of astrocyte function in neural circuits

Autor: Anja Scheller, Frank Kirchhoff, Hannah M. Jahn

Publikováno v: Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 9 (2015)

During the last two decades numerous genetic approaches affecting cell function in vivo have been developed. Current state-of-the-art technology permits the selective switching of gene function in distinct cell populations within the complex organiza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763bd9714579f8259013b24f56885fb4

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Bergmann glial AMPA receptors are required for fine motor coordination

Autor: Alexander Cupido, Rolf Sprengel, Hannah Monyer, Alexander Neumeyer, Chris I. De Zeeuw, Karim Le Meur, Magdalena Götz, Hannah M. Jahn, Aiman S. Saab, Joachim W. Deitmer, Antonia A. M. Šimek, Frank Kirchhoff, Maria E. Rubio, Anja Scheller, Henk-Jan Boele

Publikováno v: Science; Vol 337
Science, 337(6095), 749-753. American Association for the Advancement of Science
Science Magazine, 337, 749-753. American Association for the Advancement of Science (AAAS)
Science

Crucial Cerebellar Glial Cells The role of glial cells and their interaction with neurons in normal behavior is unclear. To address this question, Saab et al. (p. 749 , published online 5 July) studied a special type of glial cell in the cerebellum.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7d931562bf01e8aa3571340dbfcfbb
https://pubmed.ncbi.nlm.nih.gov/22767895

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The E3-ubiquitin ligase TRIM2 regulates neuronal polarization

Autor: Mohammad R, Khazaei, Eva C, Bunk, Anna-Lena, Hillje, Hannah M, Jahn, Eva M, Riegler, Jürgen A, Knoblich, Peter, Young, Jens C, Schwamborn

Publikováno v: Journal of neurochemistry. 117(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b934766f1b28cee56276e36ba92bfaf
https://pubmed.ncbi.nlm.nih.gov/20796172

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