Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hannah M. Gibbons"'
Autor:
Hannah M. Gibbons, Amy M. Smith, H. Heng Teoh, Peter M. Bergin, Edward W. Mee, Richard L.M. Faull, Mike Dragunow
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 1, Pp 96-103 (2011)
Valproic acid (VPA) is widely used for the treatment of mood disorders and epilepsy, but its mechanism of action is unclear. In vivo and in vitro studies using rodent models have demonstrated that VPA has both neuroprotective and neurotrophic effects
Externí odkaz:
https://doaj.org/article/b33c786b26824114880a53538b0133ce
Autor:
Mike Dragunow, Peter Bergin, Amy M. Smith, Hannah M. Gibbons, Edward W. Mee, Richard L.M. Faull, Robyn L. Oldfield
Publikováno v:
Glia. 61:929-942
Microglia are the predominant resident immune cells of the brain and can assume a range of phenotypes. They are critical for normal brain development and function but can also contribute to many disease processes. Although they are widely studied, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f51e4209194f72efe8137c131054543a
https://doi.org/10.1002/glia.22486
https://doi.org/10.1002/glia.22486
Autor:
Robyn L. Oldfield, Amy M. Smith, Mike Dragunow, Maurice A. Curtis, Hannah M. Gibbons, Edward W. Mee, Richard L.M. Faull, Peter Bergin
Publikováno v:
Journal of Neuroinflammation
Background Microglia are the primary immune cells of the brain whose phenotype largely depends on their surrounding micro-environment. Microglia respond to a multitude of soluble molecules produced by a variety of brain cells. Macrophage colony-stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5da76673b2ba6dd82087fb748ebded2
https://ora.ox.ac.uk/objects/uuid:f8da31ff-c9a2-45dc-a008-52fa42b98c6c
https://ora.ox.ac.uk/objects/uuid:f8da31ff-c9a2-45dc-a008-52fa42b98c6c
Autor:
Edward W. Mee, Hannah M. Gibbons, John Scotter, Justin Rustenhoven, Richard L.M. Faull, Jason Correia, Thomas I. H. Park, Patrick Schweder, Robyn L. Oldfield, Mike Dragunow, Peter S. Bergin, E. Scott Graham, Amy M. Smith, Maurice A. Curtis
Publikováno v:
Scientific Reports
Microglia, the resident macrophages of the central nervous system play vital roles in brain homeostasis through clearance of pathogenic material. Microglia are also implicated in neurological disorders through uncontrolled activation and inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8581ed2fce6d87997f18d31d46471cd8
Autor:
Richard L.M. Faull, Amy M. Smith, Hannah M. Gibbons, Peter Bergin, H. Heng Teoh, Mike Dragunow, Edward W. Mee
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 1, Pp 96-103 (2011)
Valproic acid (VPA) is widely used for the treatment of mood disorders and epilepsy, but its mechanism of action is unclear. In vivo and in vitro studies using rodent models have demonstrated that VPA has both neuroprotective and neurotrophic effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb93c10e0ea4a419edc55aecd068719e
https://doi.org/10.1016/j.nbd.2010.08.024
https://doi.org/10.1016/j.nbd.2010.08.024
Autor:
Edward W. Mee, Richard L.M. Faull, Mike Dragunow, Hannah M. Gibbons, Maurice A. Curtis, Y. W. J. Liu, Peter S. Bergin, H. H. Teoh, Bronwen Connor
Publikováno v:
European Journal of Neuroscience. 28:2254-2265
Mesial temporal lobe epilepsy (MTLE) is a neurological disorder associated with spontaneous recurrent complex partial seizures and hippocampal sclerosis. Although increased hippocampal neurogenesis has been reported in animal models of MTLE, increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4590a94a9f8bb2917eadc33a5fd972cb
https://doi.org/10.1111/j.1460-9568.2008.06518.x
https://doi.org/10.1111/j.1460-9568.2008.06518.x
Autor:
Jeffrey M. Greenwood, Simon J. O'Carroll, Rachel Cameron, Hannah M. Gibbons, Mike Dragunow, Andree G. Pearson, Pritika Narayan
Publikováno v:
Neuroscience. 140:1149-1156
Valproic acid is widely used for the treatment of epilepsy and mood disorders, but its mode of action is unclear. Treatment of neuronal cells with valproic acid promotes neurite sprouting, is neuroprotective and drives neurogenesis; however its effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487907e9f671c9a00e5f1f3398210dbe
https://doi.org/10.1016/j.neuroscience.2006.02.065
https://doi.org/10.1016/j.neuroscience.2006.02.065
Autor:
Alexander Muravlev, Mike Dragunow, Hannah M. Gibbons, P. Lawlor, Deborah Young, Ruian Xu, Andree G. Pearson, Janusz Lipski, Ann-Marie Woodgate, Matthew J. During, G.A. MacGibbon, M. Walton
Publikováno v:
Molecular Brain Research. 83:20-33
We investigated the function of c-Jun in PC12 cells by transfecting them with a plasmid containing a c-Jun cDNA transcription cassette. Transfected cells expressed high levels of c-Jun mRNA and protein and demonstrated an increase in both AP-1 DNA bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65178b29ea180a7f5761c4598c961443
https://doi.org/10.1016/s0169-328x(00)00191-1
https://doi.org/10.1016/s0169-328x(00)00191-1
Publikováno v:
Brain Research Protocols. 4:367-377
The rostral ventrolateral medulla (RVL) contains neurons which are critically involved in the tonic and reflex control of blood pressure. Some of these neurons project to the intermediolateral cell column of the thoracolumbar spinal cord and excite p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f9550040b758f9ae1316fab206f789
https://doi.org/10.1016/s1385-299x(99)00042-2
https://doi.org/10.1016/s1385-299x(99)00042-2
Publikováno v:
Brain Research. 830:246-257
Previous reports suggested that some neurones located in the rostral ventrolateral medulla (RVL) can act as fast oxygen sensors which enhance the sympathetic activity and blood pressure independent of peripheral chemoreceptors. The aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c1da880951797485121165f770f986
https://doi.org/10.1016/s0006-8993(99)01397-9
https://doi.org/10.1016/s0006-8993(99)01397-9