Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hannah M. Campbell"'
Autor:
Ashish N. Rao, Hannah M. Campbell, Xiangnan Guan, Tarah A. Word, Xander H.T. Wehrens, Zheng Xia, Thomas A. Cooper
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Myotonic dystrophy type 1 (DM1) is caused by a CTG repeat expansion in the DMPK gene. Expression of pathogenic expanded CUG repeat (CUGexp) RNA causes multisystemic disease by perturbing the functions of RNA-binding proteins, resulting in expression
Externí odkaz:
https://doaj.org/article/57ad09e152f94a3589084046d23de525
Autor:
Tihitina Y, Aytenfisu, Hannah M, Campbell, Mayukh, Chakrabarti, L Mario, Amzel, Sandra B, Gabelli
Publikováno v:
Current topics in microbiology and immunology. 436
This chapter is an introduction to phosphoinositide 3-kinases (PI3K), with class I PI3Ks as the central focus. First, the various PI3K isoforms in class I are presented with emphasis on their overall structure, subunits, subunit constitutive domains,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad6fa593950cf88c58a830c454af78aa
https://pubmed.ncbi.nlm.nih.gov/36243838
https://pubmed.ncbi.nlm.nih.gov/36243838
Autor:
Ann P. Quick, Hannah M. Campbell, Yuriana Aguilar-Sanchez, Xander H.T. Wehrens, Dobromir Dobrev
Publikováno v:
Cardiovasc Res
Proper cardiac Ca2+ homeostasis is essential for normal excitation–contraction coupling. Perturbations in cardiac Ca2+ handling through altered kinase activity has been implicated in altered cardiac contractility and arrhythmogenesis. Thus, a bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0e35fad410d8fcd06749fbfeefe3be
https://doi.org/10.1093/cvr/cvaa290
https://doi.org/10.1093/cvr/cvaa290
Autor:
Tihitina Y. Aytenfisu, Hannah M. Campbell, Mayukh Chakrabarti, L. Mario Amzel, Sandra B. Gabelli
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783031065651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51caa599a1faf577be1d6ea690f886da
https://doi.org/10.1007/978-3-031-06566-8_1
https://doi.org/10.1007/978-3-031-06566-8_1
Autor:
Na Li, Dobromir Dobrev, Satadru K. Lahiri, Haihao Wang, Xander H.T. Wehrens, Li Ni, Frank U. Müller, Hannah M. Campbell, Xiang Wei, Jiali Nie, Julia O. Reynolds, Xiaolu Pan, Issam Abu-Taha, Wilhelm Schmitz, Dao Wen Wang, Markus Kamler
Publikováno v:
Cardiovasc Res
Aims Abnormal intracellular calcium handling contributes to the progressive nature of atrial fibrillation (AF), the most common sustained cardiac arrhythmia. Evidence in mouse models suggests that activation of the nuclear factor of activated T-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b787a9d28967973a96e7d9a4e37bc4d2
https://europepmc.org/articles/PMC9586567/
https://europepmc.org/articles/PMC9586567/
Autor:
Na Li, Li Ni, Xiaolu Pan, Xander H.T. Wehrens, Larry D. Scott, Mohit Hulsurkar, Hannah M. Campbell, Leonne E Philippen, Katherina M. Alsina, Julia O. Reynolds, William R. Lagor
Publikováno v:
Circulation Research. 124:256-262
Rationale: Somatic overexpression in mice using an adeno-associated virus (AAV) as gene transfer vectors has become a valuable tool to analyze the roles of specific genes in cardiac diseases. The lack of atrial-specific AAV vector has been a major ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ee3f7330018ec9761f5b18bef52c14
https://doi.org/10.1161/circresaha.118.313811
https://doi.org/10.1161/circresaha.118.313811
Autor:
Thomas A. Cooper, Ashish N. Rao, Hannah M. Campbell, Tarah A. Word, Zheng Xia, Xiangnan Guan, Xander H.T. Wehrens
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight, Vol 6, Iss 5 (2021)
Myotonic dystrophy type 1 (DM1) is caused by a CTG repeat expansion in the DMPK gene. Expression of pathogenic expanded CUG repeat (CUGexp) RNA causes multisystemic disease by perturbing the functions of RNA-binding proteins, resulting in expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504d335674386d41b735d2227eb846eb
https://doi.org/10.1172/jci.insight.143465
https://doi.org/10.1172/jci.insight.143465
Autor:
Ann P. Quick, Issam Abu-Taha, Dobromir Dobrev, Eleonora Corradini, Xander H.T. Wehrens, Stephan E. Lehnart, Katherina M. Alsina, Oliver Moore, Dennis Uhlenkamp, Hannah M. Campbell, Sören Brandenburg, Tarah A. Word, Markus Kamler, David Y. Chiang, Satadru K. Lahiri, Brian Martin, Albert J. R. Heck, Mohit Hulsurkar, Carlos F. Kramm, Hui-Bin Liu
Publikováno v:
Circulation
Background: Enhanced diastolic calcium (Ca 2+ ) release through ryanodine receptor type-2 (RyR2) has been implicated in atrial fibrillation (AF) promotion. Diastolic sarcoplasmic reticulum Ca 2+ leak is caused by increased RyR2 phosphorylation by PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e334f7f21a69223f6ec395cfb20df53d
https://pubmed.ncbi.nlm.nih.gov/32955933
https://pubmed.ncbi.nlm.nih.gov/32955933
Publikováno v:
Curr Opin Cardiol
PURPOSE OF REVIEW: Atrial fibrillation is a common cardiac arrhythmia with a high morbidity and mortality affecting 34 million worldwide. Current therapies are inadequate and often fail to directly address molecular mechanisms of the disease. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7895c15406c68464f3374503d08475c5
https://doi.org/10.1097/hco.0000000000000505
https://doi.org/10.1097/hco.0000000000000505
Autor:
Xander H.T. Wehrens, Oliver Moore, Hannah M. Campbell, Jayso'n Davidson, William R. Lagor, Tarah A. Word, Juwan Copeland
Publikováno v:
Heart Rhythm. 18:S467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278342017463f137d8ac4a9dfed6756c
https://doi.org/10.1016/j.hrthm.2021.06.1152
https://doi.org/10.1016/j.hrthm.2021.06.1152