Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hannah M Smith"'
Autor:
Robert F Hillary, Daniel L McCartney, Hannah M Smith, Elena Bernabeu, Danni A Gadd, Aleksandra D Chybowska, Yipeng Cheng, Lee Murphy, Nicola Wrobel, Archie Campbell, Rosie M Walker, Caroline Hayward, Kathryn L Evans, Andrew M McIntosh, Riccardo E Marioni
Publikováno v:
PLoS Medicine, Vol 20, Iss 7, p e1004247 (2023)
BackgroundDNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) investigate the strength of association between methylation at individual CpG si
Externí odkaz:
https://doaj.org/article/f0b1e6cceb97419e8873e65cb9b0489b
Autor:
Danni A. Gadd, Hannah M. Smith, Donncha Mullin, Ola Chybowska, Robert F. Hillary, Dorien M. Kimenai, Elena Bernabeu, Yipeng Cheng, Chloe Fawns-Ritchie, Archie Campbell, Danielle Page, Adele Taylor, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Rosie M. Walker, Kathryn L. Evans, Andrew M. McIntosh, Caroline Hayward, Tom C. Russ, Sarah E. Harris, Paul Welsh, Naveed Sattar, Simon R. Cox, Daniel L. McCartney, Riccardo E. Marioni
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Plasma growth differentiation factor 15 (GDF15) and N‐terminal proB‐type natriuretic peptide (NT‐proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for GDF15 and NT-p
Externí odkaz:
https://doaj.org/article/76e8233ab631452ab514eb985f52d351
Autor:
Paulina D. Ketcham, Felisha Imholt, Mingquan Yan, Hannah M. Smith, Shabistan Asrar, Ling Yu, Connor P. Dolan, Osama Qureshi, Yu‐Lieh Lin, Ian Xia, Patrick C. Hall, Alyssa R. Falck, Kirby M. Sherman, Dana Gaddy, Larry J. Suva, Ken Muneoka, Regina Brunauer, Lindsay A. Dawson
Publikováno v:
Wound Repair and Regeneration. 31:17-27
Humans and mice have the ability to regenerate the distal digit tip, the terminal phalanx (P3) in response to amputation. What distinguishes P3 regeneration from regenerative failure is formation of the blastema, a proliferative structure that underg
Autor:
Connor P. Dolan, Felisha Imholt, Mingquan Yan, Tae-Jung Yang, Joshua Gregory, Osama Qureshi, Katherine Zimmel, Kirby M. Sherman, Hannah M. Smith, Alyssa Falck, Eric Leininger, Ling Yu, Regina Brunauer, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka
Publikováno v:
Dev Biol
It is long-established that innervation-dependent production of neurotrophic factors is required for blastema formation and epimorphic regeneration of appendages in fish and amphibians. The regenerating mouse digit tip and the human fingertip are mam
Autor:
Robert F. Hillary, Daniel L. McCartney, Elena Bernabeu, Danni A. Gadd, Yipeng Cheng, Aleksandra D. Chybowska, Hannah M. Smith, Lee Murphy, Nicola Wrobel, Archie Campbell, Rosie M. Walker, Caroline Hayward, Kathryn L. Evans, Andrew M. McIntosh, Riccardo E. Marioni
BackgroundBlood DNA methylation can inform us about the biological mechanisms that underlie common disease states. Previous epigenome-wide analyses of common diseases often focus solely on the prevalence or incidence of individual conditions and rely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04079ee578250e30d274cf67bf95042f
https://doi.org/10.1101/2023.01.10.23284387
https://doi.org/10.1101/2023.01.10.23284387
Autor:
C.E. Lominska, Colby D. Spiess, Ajay Tejwani, Scott Weir, Kiersten L. Berggren, Sufi M. Thomas, Deri Morgan, Gregory N Gan, Hannah M. Smith
Publikováno v:
Mol Carcinog
Cancer and the immune system share an intimate relationship. Chronic inflammation increases the risk of cancer occurrence and can also drive inflammatory mediators into the tumor microenvironment enhancing tumor growth and survival. The p38 MAPK path
Autor:
Candyce M, Sturgeon, Nicholas, Zanghi, Hannah M, Smith, Emily K, Davis, Meaghan R, Robinson, Elizabeth, Cabrera, Molly C, Holbrook, Verónica A, Segarra
Large-scale studies have localized the uncharacterized YML018C protein to the vacuolar membrane and have identified the autophagy-related protein Atg27p as one of its 10 physical interactors (Huh et al., 2003; Tarasov et al., 2008). These two finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52293f93bbbbed6b291fedd4c8aa462
Publikováno v:
Journal of hand surgery global online. 2(3)
Purpose The region of the index finger metacarpophalangeal joint is a common source of hand pain with variable, well-known etiologies. We have identified the tubercle at the dorsoradial neck of the index finger metacarpal as a distinct and specific s
Publikováno v:
Journal of Burn Care & Research. 41:S117-S118
Introduction Gasoline burns represent a significant source of preventable morbidity each year. Often used inappropriately as an accelerant, gasoline is substantially more volatile than other commonly used accelerants due to its low flash point and va
Publikováno v:
Cell Chemical Biology. 25:996-1005.e4
The discovery of mutant or fusion kinases that drive oncogenesis, and the subsequent approval of specific inhibitors for these enzymes, has been instrumental in the management of some cancers. However, acquired resistance remains a significant proble