Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hannah M Kolev"'
Telomouse—a mouse model with human-length telomeres generated by a single amino acid change in RTEL1
Autor:
Riham Smoom, Catherine Lee May, Vivian Ortiz, Mark Tigue, Hannah M. Kolev, Melissa Rowe, Yitzhak Reizel, Ashleigh Morgan, Nachshon Egyes, Dan Lichtental, Emmanuel Skordalakes, Klaus H. Kaestner, Yehuda Tzfati
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Telomeres, the ends of eukaryotic chromosomes, protect genome integrity and enable cell proliferation. Maintaining optimal telomere length in the germline and throughout life limits the risk of cancer and enables healthy aging. Telomeres in
Externí odkaz:
https://doaj.org/article/1ec8f8f1cc1c4bba80901ee1adb464df
Autor:
Hannah M. Kolev, Klaus H. Kaestner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 5, Pp 809-821 (2023)
The development of the mammalian intestine, from its earliest origins as a morphologically uniform sheet of endoderm cells during gastrulation into the complex organ system that is essential for the life of the organism, is a truly fascinating proces
Externí odkaz:
https://doaj.org/article/8a5c13747fe54ea6b79123fc6cd1c659
Autor:
Hannah M. Kolev, Avital Swisa, Elisabetta Manduchi, Yemin Lan, Rachel R. Stine, Giuseppe Testa, Klaus H. Kaestner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 821-839 (2023)
Background & Aims: Although trimethylation of histone H3 lysine 27 (H3K27me3) by polycomb repressive complex 2 is required for intestinal function, the role of the antagonistic process—H3K27me3 demethylation—in the intestine remains unknown. The
Externí odkaz:
https://doaj.org/article/a95e54038c994905928595d51e834d0f
Autor:
Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams‐Tzivelekidis, Yuhua Tian, Patrick A Williams, N Adrian Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton
Publikováno v:
EMBO reports. 23(11)
The intestinal epithelium exhibits a rapid and efficient regenerative response to injury. Emerging evidence supports a model where plasticity of differentiated cells, particularly those in the secretory lineages, contributes to epithelial regeneratio
Autor:
Riham Smoom, Catherine Lee May, Vivian Ortiz, Mark Tigue, Hannah M. Kolev, Melissa Rowe, Yitzhak Reizel, Ashleigh Morgan, Nachshon Egyes, Dan Lichtental, Emmanuel Skordalakes, Klaus H. Kaestner, Yehuda Tzfati
Telomeres, the ends of eukaryotic chromosomes, protect genome integrity and enable cell proliferation. Maintaining optimal telomere length in the germline and throughout life limits the risk of cancer and enables healthy aging. Telomeres in the house
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3b260fea454b269889d4ef860f3f7c
https://doi.org/10.1101/2021.06.06.447246
https://doi.org/10.1101/2021.06.06.447246
Autor:
Scott A. Keith, Annie Park, Hannah M. Kolev, Jonathan S. Minden, Rory Eutsey, Jonathan Huang, Brooke M. McCartney, Luisa Hiller N, Malachi A. Blundon, Pyzel Am, Nigel S. Atkinson, Stacie L. Oliver, Lau Tw
SummaryThe gut microbiota impacts diverse aspects of host biology including metabolism, immunity, and behavior, but the scope of those effects and their underlying molecular mechanisms are poorly understood. To address these gaps, we used Two-dimensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a026449e852aca664ba70bda9692c79
Autor:
Filippa G. Bagnasco, Melinda Harrison, Garrett Finn, David Dunbar, Machika Kaku, Rahat M. Aziz, Rodney A. King, Marisa Egan, Nitish S. Chimalakonda, Hannah M. Kolev, Daniel R. Evans, Allen W. Karstens, Christopher M. McDaniel, Lee E. Hughes, Megan L. Archambault, Marie C. Pizzorno, Jennifer E. Menninger, Robert C. Benjamin, Emily M. Lehmann, Karen K. Klyczek, Jakob R. Yankauskas, Hannah McDonald, Amelia M. Schick, Josephine E. Minick, Deborah Jacobs-Sera, Jade Connor, Megan C. Hartwell, Kayla M. Robinson, Haley Broomell, Kaitlyn E. Wathen, Kelly C. Lynch, Julia Y. Lee-Soety, Victoria A. Rose, Emily L. Stowe, Vassie C. Ware, Daniel S. Thomas, Bobby L. Gaffney, Shawn C. London, Daniel A. Russell, Kathryn M. Hyduchak, Jonathan L. Weinstein, Yasmene M. Warrad, Christine Zhang, Zachary T. Vonberg, Sarah Ball, Lorianna Vanderveen, Christopher J. Blasi, Corrina Tender, Morgan P. Silva, Katelyn M. Pruett, Claire A. Rinehart, Trevor Cross, Allison R. Thompson, Jeremy W. Sieker, Carter N. Lantz, Carlos A. Guerrero Bustamante, Katherine Borst, Jessica A. Dahlke, William Casazza, Cassandra T. Ott, Sarah K. Pellerino, Kelly E. Garrigan, J. Alfred Bonilla, Zachary S. Brynell, Morgan E. Lamey, Aswathi E. Jacob, Kate Allen, Emma A. Sweet, Francis E. Mele, Sierra N. Miller, Dylan Chudoff, Ashley B. Bue, Julia Schlossman, Graham F. Hatfull, Margaret A. Kenna, Kevin Hong Chen, Conner B. Brown, Christopher R. Fratus, Quynh D. Vo, Martha Nkangabwa, Mary A. Braun, Sydney O. Burke, Natalie Barrett, Bryan C. Gibbon, Courtney T. Nabua, Catherine M. Mageeney, William J. Pinamont, Stephanie E. Simon, Porter T. Swartz, Milan Dolan, Rohan Varma, Temiloluwa O. Lawson, Ross T. Pirnie, Kevin J. Mathew, Caroline K. Napoli, Rebecca A. Garlena, Jessica E. Medrano, Bethany M. Deaton, Welkin H. Pope, Chrystal Thomas, Michael A. Goedde, Amal Farooq, Gabbi Rickstrew, Hannah L. Vaught, A. Javier Lopez, Noah A. Stueven, Amanda L. Kobokovich, Tamarah L. Adair, Elizabeth A. Oates, Jacqueline F. Wyper, Elizabeth Kriese, Victoria M. Schneider, Susheel K. Khetarpal, Emily L. Heckman, Abby K. Fahnestock, Emilee J. Plautz, Travis N. Mavrich, Amanda K. Staples, Jonathan S. Lapin, Danielle M. DeNigris, Katrina Terry, In Young Lee, Sai A. Konde, Chloe A. Sells, Jennifer Huang, Marissa M. Silvi, Tetyana Martynyuk, Katherine C. DeRuff, Isabelle L. Steed, Kyra N. Curtis, Sarah J. Degroote, Scott M. Lee, Patrick A. Rimple, C. Joel McManus, Abigail T. Sweetman, Julia A. Cautela, Patricia Afram
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180517 (2017)
PLoS ONE
PLoS ONE
The vast bacteriophage population harbors an immense reservoir of genetic information. Almost 2000 phage genomes have been sequenced from phages infecting hosts in the phylum Actinobacteria, and analysis of these genomes reveals substantial diversity
Autor:
Hannah M. Kolev, Ezgi Kunttas-Tatli, Jonathan S. Minden, Danielle R. Schlesinger, David A. Vinson, Brooke M. McCartney, Amritha Parthasarathy, Malachi A. Blundon, Samantha L. Smith
Publikováno v:
Development (Cambridge, England). 143(14)
Wnt signaling generates patterns in all embryos, from flies to humans, and controls cell fate, proliferation, and metabolic homeostasis. Inappropriate Wnt pathway activation results in diseases, including colorectal cancer. The Adenomatous polyposis