Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hannah Louise Neumaier"'
Autor:
Hannah Louise Neumaier, Shelly Harel, Karin Klingel, Ziya Kaya, Arnd Heuser, Meike Kespohl, Antje Beling
Publikováno v:
Cells, Vol 9, Iss 5, p 1093 (2020)
Inhibition of proteasome function by small molecules is highly efficacious in cancer treatment. Other than non-selective proteasome inhibitors, immunoproteasome-specific inhibitors allow for specific targeting of the proteasome in immune cells and th
Externí odkaz:
https://doaj.org/article/c2891531edc74ebe8d9979c4098a2815
Autor:
Nadine Althof, Karin Klingel, Arndt Heuser, Hannah Louise Neumaier, Ziya Kaya, Antje Beling, Meike Kespohl, Carl Christoph Goetzke
Publikováno v:
Basic Research in Cardiology
A preclinical model of troponin I-induced myocarditis (AM) revealed a prominent role of the immunoproteasome (ip), the main immune cell-resident proteasome isoform, in heart-directed autoimmunity. Viral infection of the heart is a known trigger of ca
Autor:
Hannah Louise Neumaier, Christin Meckes, Christian Salbach, Meike Kespohl, Ulf Landmesser, Carl Christoph Goetzke, Benjamin Meder, Antje Beling, Lorenz H. Lehmann, January Weiner, Andrea Fischer, Adelheid Kratzer, Hugo A. Katus, Ziya Kaya, Anna-Maria Müller, Karin Klingel, Mirjam Schenk, Arnd Heuser, Mariella Bockstahler, Martina Sauter
Publikováno v:
Bockstahler, Mariella; Fischer, Andrea; Goetzke, Carl Christoph; Neumaier, Hannah Louise; Sauter, Martina; Kespohl, Meike; Müller, Anna-Maria; Meckes, Christin; Salbach, Christian; Schenk, Mirjam; Heuser, Arnd; Landmesser, Ulf; Weiner, January; Meder, Benjamin; Lehmann, Lorenz; Kratzer, Adelheid; Klingel, Karin; Katus, Hugo A.; Kaya, Ziya and Beling, Antje (2020). Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation. Circulation, 141(23), pp. 1885-1902. American Heart Association 10.1161/circulationaha.119.043171
Background: Immune checkpoint inhibitor (ICI) therapy is often accompanied by immune-related pathology, with an increasing occurrence of high-risk ICI-related myocarditis. Understanding the mechanisms involved in this side effect could enable the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a750717bbca372c1b2e77483b5a8a05
http://edoc.mdc-berlin.de/18806/7/18806suppl.zip
http://edoc.mdc-berlin.de/18806/7/18806suppl.zip