Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hannah Lees"'
Autor:
Hannah Lees, Jonathan Swann, Simon M Poucher, Jeremy K Nicholson, Elaine Holmes, Ian D Wilson, Julian R Marchesi
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e100916 (2014)
Animal models are invaluable tools which allow us to investigate the microbiome-host dialogue. However, experimental design introduces biases in the data that we collect, also potentially leading to biased conclusions. With obesity at pandemic levels
Externí odkaz:
https://doaj.org/article/644d55be95c84a4dafd6463d20a3a45e
Autor:
Kristin L. Granlund, Fayyaz Ahamed, Micaela Millan, Roozbeh Eskandari, Kayvan R. Keshari, Sangmoo Jeong, Hannah Lees
Publikováno v:
NMR Biomed
Hyperpolarized [1-(13)C] pyruvate can be used to examine the metabolic state of cancer cells, highlighting a key metabolic characteristic of cancer: the upregulated metabolic flux to lactate, even in the presence of oxygen (Warburg effect). Thus, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d07987ac52691af3410198521b96a6f
https://europepmc.org/articles/PMC8288443/
https://europepmc.org/articles/PMC8288443/
Autor:
Simon M. Poucher, Hannah Lees, Ian D. Wilson, Elaine Holmes, Jeremy K. Nicholson, Jonathan R. Swann
Publikováno v:
Journal of proteome research. 18(5)
Obesity and its comorbidities are increasing worldwide imposing a heavy socioeconomic burden. The effects of obesity on the metabolic profiles of tissues (liver, kidney, pancreas), urine, and the systemic circulation were investigated in the Zucker r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc558dfad2645cda8f09d7c6aab5f191
https://pubmed.ncbi.nlm.nih.gov/30939873
https://pubmed.ncbi.nlm.nih.gov/30939873
Autor:
Matthew B. Biggs, Hannah Lees, Jason A. Papin, Thomas J. Moutinho, Jonathan R. Swann, Gregory L. Medlock, Glynis L. Kolling
Publikováno v:
The ISME Journal
The altered Schaedler flora (ASF) is a model microbial community with both in vivo and in vitro relevance. Here we provide the first characterization of the ASF community in vitro, independent of a murine host. We compared the functional genetic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ca2edf7760d83e2b527621f651a21d
https://doi.org/10.1038/ismej.2016.130
https://doi.org/10.1038/ismej.2016.130
Autor:
Jia V. Li, Elaine Holmes, Jutarop Phetcharaburanin, Jeremy K. Nicholson, Julian R. Marchesi, Florian Seyfried, Hannah Lees
Publikováno v:
Journal of Proteome Research. 15:1897-1906
The Zucker (fa/fa) rat is a valuable and extensively utilized model for obesity research. However, the metabolic networks underlying the systemic response in the obese Zucker rats remain to be elucidated. This information is important to further our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62c82af74d15a9a3f44c729239954c1
https://doi.org/10.1021/acs.jproteome.6b00090
https://doi.org/10.1021/acs.jproteome.6b00090
Autor:
Jeremy K. Nicholson, Ian D. Wilson, Simon M. Poucher, Elaine Holmes, Julian R. Marchesi, Jonathan R. Swann, Hannah Lees
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e100916 (2014)
PLoS ONE, Vol 9, Iss 9, p e100916 (2014)
Animal models are invaluable tools which allow us to investigate the microbiome-host dialogue. However, experimental design introduces biases in the data that we collect, also potentially leading to biased conclusions. With obesity at pandemic levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f2f343f1f51f4b85264c993600cdbf
http://hdl.handle.net/10044/1/34223
http://hdl.handle.net/10044/1/34223
Publikováno v:
Journal of proteome research. 12(4)
Hippurate, the glycine conjugate of benzoic acid, is a normal constituent of the endogenous urinary metabolite profile and has long been associated with the microbial degradation of certain dietary components, hepatic function and toluene exposure, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177026be82cdc7b71c747b13b23a45d5
https://pubmed.ncbi.nlm.nih.gov/23342949
https://pubmed.ncbi.nlm.nih.gov/23342949