Výsledky vyhledávání - "Hannah L. Simpson"

Akademický článek

Soluble Non-Starch Polysaccharides From Plantain (Musa x paradisiaca L.) Diminish Epithelial Impact of Clostridioides difficile

Autor: Hannah L. Simpson, Carol L. Roberts, Louise M. Thompson, Cameron R. Leiper, Nehana Gittens, Ellie Trotter, Carrie A. Duckworth, Stamatia Papoutsopoulou, Fabio Miyajima, Paul Roberts, Niamh O’Kennedy, Jonathan M. Rhodes, Barry J. Campbell

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Clostridioides difficile infection (CDI) is a leading cause of antibiotic-associated diarrhoea. Adhesion of this Gram-positive pathogen to the intestinal epithelium is a crucial step in CDI, with recurrence and relapse of disease dependent on epithel

Externí odkaz: https://doaj.org/article/867acb7cde0d44d4a188a5bd42a14a9e

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Akademický článek

Dietary supplementation with soluble plantain non-starch polysaccharides inhibits intestinal invasion of Salmonella Typhimurium in the chicken.

Autor: Bryony N Parsons, Paul Wigley, Hannah L Simpson, Jonathan M Williams, Suzie Humphrey, Anne-Marie Salisbury, Alastair J M Watson, Stephen C Fry, David O'Brien, Carol L Roberts, Niamh O'Kennedy, Asa V Keita, Johan D Söderholm, Jonathan M Rhodes, Barry J Campbell

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87658 (2014)

Soluble fibres (non-starch polysaccharides, NSP) from edible plants but particularly plantain banana (Musa spp.), have been shown in vitro and ex vivo to prevent various enteric pathogens from adhering to, or translocating across, the human intestina

Externí odkaz: https://doaj.org/article/c9650eb50de44dbd8d9db0a1f8f63863

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IBD: Microbiota Manipulation through Diet and Modified Bacteria

Autor: Jonathan M. Rhodes, Barry J. Campbell, Hannah L. Simpson

Publikováno v: Digestive Diseases. 32:18-25

Background/Aims: Crohn's disease (CD) and ulcerative colitis (UC) are both typified by an altered intestinal microbiota, and gene associations imply various defects in the mucosal barrier and in the innate immune response to bacteria. This review aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50b0f3e14112d3fd97cbd7c192697fd
https://doi.org/10.1159/000367821

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Dietary Supplementation with Soluble Plantain Non-Starch Polysaccharides Inhibits Intestinal Invasion of Salmonella Typhimurium in the Chicken

Autor: Jonathan M. Rhodes, Anne-Marie Salisbury, Hannah L. Simpson, David O'Brien, Bryony N. Parsons, Jonathan M. Williams, Niamh O'Kennedy, Carol L. Roberts, Barry J. Campbell, Suzie Humphrey, Paul Wigley, Johan D. Söderholm, Alastair J.M. Watson, Åsa V. Keita, Stephen C. Fry

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87658 (2014)
PLoS ONE
Parsons, B N, Wigley, P, Simpson, H L, Williams, J M, Humphrey, S, Salisbury, A-M, Watson, A J M, Fry, S C, O'Brien, D, Roberts, C L, O'Kennedy, N, Keita, A V, Söderholm, J D, Rhodes, J M & Campbell, B J 2014, ' Dietary supplementation with soluble plantain non-starch polysaccharides inhibits intestinal invasion of salmonella typhimurium in the chicken ', PLoS ONE, vol. 9, no. 2, e87658 . https://doi.org/10.1371/journal.pone.0087658

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0c3275e1ca3503ea7b19131600079a
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105237

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Sa1779 Soluble Plantain (Banana) Fibre Inhibits Epithelial Cell Damage in Response to Clostridium difficile and Its Toxins

Autor: Barry J. Campbell, Jonathan M. Rhodes, Hannah L. Simpson

Publikováno v: Gastroenterology. 148:S-330

G A A b st ra ct s fecal BA loss, which occurs in the absence of any absorptive defect within the terminal ileum, is due to increased BA synthesis, resulting from impaired FGF19 ileal production or hepatic actions. We aimed to investigate whether BA-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5390d3b444968075e5c4cdc1109f7f86
https://doi.org/10.1016/s0016-5085(15)31095-7

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PTH-140 Soluble Plantain Fibre Inhibits The Epithelial Adhesion Of Diarrhoeal Pathogens Clostridium Difficile, Salmonella And Enterotoxigenic E. Coli (etec) Through Interaction With The Intestinal Epithelium

Autor: Barry J. Campbell, Hannah L. Simpson, Jonathan M. Rhodes, Åsa V. Keita, Johan D. Söderholm

Publikováno v: Gut. 63:A273.2-A274

Introduction Pathogen-related diarrhoea causes significant morbidity and mortality worldwide. Our studies have previously shown that soluble dietary fibre (non-starch polysaccharides, NSP), particularly from plantain bananas, can inhibit epithelial a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6378a189682ee5843cca4225778dd009
https://doi.org/10.1136/gutjnl-2014-307263.586

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PWE-180 The Acidic Polysaccharide Component of Soluble Plantain Fibre Inhibits the Adhesion of Diarrhoea-Associated Pathogens Salmonella, Clostridium Difficile and Enterotoxigenic Escherichia Coli to Intestinal Epithelial Cells

Autor: Hannah L. Simpson, Barry J. Campbell, Jonathan M. Rhodes, Bryony N. Parsons

Publikováno v: Gut. 62:A203.3-A204

Introduction Pathogen-related diarrhoea is a major problem worldwide, causing significant morbidity and mortality each year. Our recent studies have shown that soluble dietary fibre (non-starch polysaccharides, NSP), particularly those from plantain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80a16801bd89bc9d000875975a657cc1
https://doi.org/10.1136/gutjnl-2013-304907.468

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PMO-030 Soluble plant fibres, particularly leek and plantain, inhibit adherence of diarrhoea-associated pathogensC difficileand enterotoxigenicEscherichia colito intestinal epithelial cells

Autor: Carol L. Roberts, Jonathan M. Rhodes, Barry J. Campbell, Hannah L. Simpson

Publikováno v: Gut. 61:A85.2-A85

Introduction It has long been thought that dietary fibre promotes intestinal health and we have previously shown that the soluble non-starch polysaccharide (NSP) from plantain bananas ( Musa spp.) can inhibit the epithelial adhesion and microfold (M)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::891a0a7d8137a907bb84891dd49400f0
https://doi.org/10.1136/gutjnl-2012-302514b.30

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