Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hannah L. H. Lai"'
Autor:
Phuong H. D. Nguyen, Martin Wasser, Chong Teik Tan, Chun Jye Lim, Hannah L. H. Lai, Justine Jia Wen Seow, Ramanuj DasGupta, Cheryl Z. J. Phua, Siming Ma, Jicheng Yang, Sheena D/O Suthen, Wai Leong Tam, Tony K. H. Lim, Joe Yeong, Wei Qiang Leow, Yin Huei Pang, Gwyneth Soon, Tracy Jiezhen Loh, Wei Keat Wan, Chung Yip Chan, Peng Chung Cheow, Han Chong Toh, Alfred Kow, Yock Young Dan, Juinn Huar Kam, Shridhar Iyer, Krishnakumar Madhavan, Alexander Chung, Glenn K. Bonney, Brian K. P. Goh, Naiyang Fu, Victor C. Yu, Weiwei Zhai, Salvatore Albani, Pierce K. H. Chow, Valerie Chew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
In order to design cancer immune therapies, it is important to understand how tumours evade the immune response that is mounted against them. Authors here analyse the distribution and properties of immune cells in hepatocellular carcinoma and describ
Externí odkaz:
https://doaj.org/article/2648047cd2d74e93ad29e2f0557f8fa3
Autor:
Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Intratumoural heterogeneity is a feature of liver cancer. Here, the authors demonstrate that heterogeneity exists at the immune cell level in liver cancer and show that tumours with high intratumoural immune heterogeneity demonstrated an immune suppr
Externí odkaz:
https://doaj.org/article/04bfa3244f6242d895349149a2c716b4
Autor:
Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Glen K. Bonney, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21556-y.
Externí odkaz:
https://doaj.org/article/08ad460145fc4cdeaa1c1a80cb3d6247
Autor:
Yun Hua, Lee, Samuel, Chuah, Phuong H D, Nguyen, Chun Jye, Lim, Hannah L H, Lai, Martin, Wasser, Camillus, Chua, Tony K H, Lim, Wei Qiang, Leow, Tracy Jiezhen, Loh, Wei Keat, Wan, Yin Huei, Pang, Gwyneth, Soon, Peng Chung, Cheow, Juinn Huar, Kam, Shridhar, Iyer, Alfred, Kow, Glenn K, Bonney, Chung Yip, Chan, Alexander, Chung, Brian K P, Goh, Weiwei, Zhai, Pierce K H, Chow, Salvatore, Albani, Haiyan, Liu, Valerie, Chew
Publikováno v:
Cancer letters. 552
IL-17-producing CD8 (Tc17) T cells have been shown to play an important role in infection and chronic inflammation, however their implications in hepatocellular carcinoma (HCC) remain elusive. In this study, we performed cytometry by time-of-flight (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3328919b356377f688b89993cdedb9d5
https://pubmed.ncbi.nlm.nih.gov/36279983
https://pubmed.ncbi.nlm.nih.gov/36279983
Autor:
Sheena Suthen, Chun Jye Lim, Phuong H. D. Nguyen, Charles‐Antoine Dutertre, Hannah L. H. Lai, Martin Wasser, Camillus Chua, Tony K. H. Lim, Wei Qiang Leow, Tracy Jiezhen Loh, Wei Keat Wan, Yin Huei Pang, Gwyneth Soon, Peng Chung Cheow, Juinn Huar Kam, Shridhar Iyer, Alfred Kow, Wai Leong Tam, Timothy W. H. Shuen, Han Chong Toh, Yock Young Dan, Glenn K. Bonney, Chung Yip Chan, Alexander Chung, Brian K. P. Goh, Weiwei Zhai, Florent Ginhoux, Pierce K. H. Chow, Salvatore Albani, Valerie Chew
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES. 76(5)
Hypoxia is one of the central players in shaping the immune context of the tumor microenvironment (TME). However, the complex interplay between immune cell infiltrates within the hypoxic TME of HCC remains to be elucidated.We analyzed the immune land
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cce818f178ec65548d292ecfda999f6
https://pubmed.ncbi.nlm.nih.gov/35184329
https://pubmed.ncbi.nlm.nih.gov/35184329
Autor:
Phuong H. D. Nguyen, Martin Wasser, Chong Teik Tan, Chun Jye Lim, Hannah L. H. Lai, Justine Jia Wen Seow, Ramanuj DasGupta, Cheryl Z. J. Phua, Siming Ma, Jicheng Yang, Sheena D/O Suthen, Wai Leong Tam, Tony K. H. Lim, Joe Yeong, Wei Qiang Leow, Yin Huei Pang, Gwyneth Soon, Tracy Jiezhen Loh, Wei Keat Wan, Chung Yip Chan, Peng Chung Cheow, Han Chong Toh, Alfred Kow, Yock Young Dan, Juinn Huar Kam, Shridhar Iyer, Krishnakumar Madhavan, Alexander Chung, Glenn K. Bonney, Brian K. P. Goh, Naiyang Fu, Victor C. Yu, Weiwei Zhai, Salvatore Albani, Pierce K. H. Chow, Valerie Chew
Publikováno v:
Nature communications. 13(1)
Immune evasion is key to cancer initiation and later at metastasis, but its dynamics at intermediate stages, where potential therapeutic interventions could be applied, is undefined. Here we show, using multi-dimensional analyses of resected tumours,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cb02d0e9a7bbae5f99fa6d5417e9d7
https://pubmed.ncbi.nlm.nih.gov/35301339
https://pubmed.ncbi.nlm.nih.gov/35301339
Autor:
Liyun Lai, Neslihan A. Kaya, Tony Kiat-Hon Lim, Phuong H. D. Nguyen, Florent Ginhoux, Brian K. P. Goh, Siming Ma, Salvatore Albani, Alexander Y. F. Chung, Glen K. Bonney, Wei Qiang Leow, Weiwei Zhai, Shridhar Ganpathi Iyer, Wei Keat Wan, Chun Jye Lim, Yock Young Dan, Tracy Loh, Cheryl Zi Jin Phua, Valerie Chew, Yin Huei Pang, Pierce K. H. Chow, Martin Wasser, Jia Qi Lim, Hannah L. H. Lai, Alfred Wei Chieh Kow, Peng Chung Cheow, Han Chong Toh, Ser Yee Lee, Chung Yip Chan, Wai Leong Tam
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The clinical relevance of immune landscape intratumoural heterogeneity (immune-ITH) and its role in tumour evolution remain largely unexplored. Here, we uncover significant spatial and phenotypic immune-ITH from multiple tumour sectors and decipher i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf18c546f416058fcadc5df0045e941
https://pubmed.ncbi.nlm.nih.gov/33623020
https://pubmed.ncbi.nlm.nih.gov/33623020
Autor:
Yock Young Dan, Alexander Y. F. Chung, Brian K. P. Goh, Florent Ginhoux, Wei Keat Wan, Phuong H. D. Nguyen, Ser Yee Lee, Alfred Wei Chieh Kow, Tony Kiat-Hon Lim, Martin Wasser, Peng Chung Cheow, Wai Leong Tam, Jia Qi Lim, Chung Yip Chan, Chun Jye Lim, Shridhar Ganpathi Iyer, Salvatore Albani, Cheryl Zi Jin Phua, Wei Qiang Leow, Weiwei Zhai, Valerie Chew, Siming Ma, Glen K. Bonney, Tracy Loh, Hannah L. H. Lai, Yin Huei Pang, Han Chong Toh, Liyun Lai, Pierce K. H. Chow, Neslihan A. Kaya
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21556-y.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a396366258e367cb1f28b85b3e3697f1
https://doaj.org/article/08ad460145fc4cdeaa1c1a80cb3d6247
https://doaj.org/article/08ad460145fc4cdeaa1c1a80cb3d6247