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of 10
pro vyhledávání: '"Hannah L. F. Swa"'
Autor:
Hannah L. F. Swa, Buddhi N. T. Fernando, Shakila Premarathna, Asfa Alli-Shaik, Zeid Badurdeen, Jayantha Gunarathna, Nishantha Nanayakkara
Publikováno v:
Kidney and Dialysis, Vol 2, Iss 4, Pp 576-587 (2022)
Background: A chronic interstitial disease, chronic kidney disease of uncertain etiology (CKDu), has emerged as a notable contributor to the CKD burden in rural Sri Lanka. Most therapeutic and diagnostic approaches to CKD focus on glomerular diseases
Externí odkaz:
https://doaj.org/article/9142ed04d2a9471993fd93251e0af67e
Autor:
Nishantha Nanayakkara, Hannah L F Swa, Buddhi N.T. Fernando, Shakila Premaratne, Asfa Alli-Shaik, Zeid Badurdeen, Jayantha Gunarathne
IntroductionA chronic interstitial disease, chronic kidney disease of uncertain etiology (CKDu) has emerged as a notable contributor to the CKD burden in rural Sri Lanka. Most therapeutic and diagnostic approaches of CKD are focusing towards glomerul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4d2d29825dc84585df6bc0109a9bafc
https://doi.org/10.21203/rs.3.rs-1494104/v1
https://doi.org/10.21203/rs.3.rs-1494104/v1
Autor:
Lee Ching Ng, Hannah L. F. Swa, Yee Sin Leo, Wei-Ping Tien, Asfa Alli-Shaik, Hapuarachchige Chanditha Hapuarachchi, Sheena Wee, Vanessa W. Lim, Relus Kek, Jayantha Gunaratne
Targeted proteomic mass spectrometry is emerging as a salient clinical diagnostic tool to track protein biomarkers. However, its strong analytical properties have not been exploited in the diagnosis and typing of flaviviruses. Here, we report the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316d4fdccfd84db4f60919f478377b38
https://hdl.handle.net/10356/151418
https://hdl.handle.net/10356/151418
Autor:
Hyungwon Choi, Hannah L. F. Swa, Jayantha Gunaratne, Damian Fermin, Siok Ghee Ler, Hiromi W. L. Koh
Publikováno v:
PROTEOMICS. 15:2580-2591
Labeling-based proteomics is a powerful method for detection of differentially expressed proteins (DEPs). The current data analysis platform typically relies on protein-level ratios, which is obtained by summarizing peptide-level ratios for each prot
Publikováno v:
PROTEOMICS. 15:408-418
Annexin-1 (ANXA1) is known to be involved in important cellular processes and implicated in cancer. Our previous study showed its roles in cell migration and DNA-damage response processes in breast cancer initiation. In order to understand its roles
Autor:
Xiao-He Shi, Weiping Han, Hannah L. F. Swa, Ernesto Guccione, Joy Lim, Qiling Zhou, Aimin Xu, Marco Bezzi, Ee Tsin Wong, Masahito Ikawa, Jayantha Gunaratne, Beiying Qiu, Wanjin Hong, Kenneth K.Y. Cheng, Manikandan Lakshmanan, Semih Can Akıncılar, Karen S.L. Lam, Vinay Tergaonkar, Diana Low, Jill M. Tham
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1876-1886 (2014)
Beiying Qiu, Xiaohe Shi, EeTsin Wong, Joy Lim, Marco Bezzi, Diana Low, Qiling Zhou, SemihCan Akıncılar, Manikandan Lakshmanan, HannahL.F. Swa, JillMaeLan Tham, Jayantha Gunaratne, KennethK.Y. Cheng, Wanjin Hong, KarenS.L. Lam, Masahito Ikawa, Ernes
Autor:
Thomas Leung, Felicia P. L. Tay, Hannah L. F. Swa, Jayantha Gunaratne, Jing-Ming Dong, Edward Manser, Brian Burke
Publikováno v:
Science Signaling. 9
Focal adhesions are protein complexes that link metazoan cells to the extracellular matrix through the integrin family of transmembrane proteins. Integrins recruit many proteins to these complexes, referred to as the "adhesome." We used proximity-dep
Autor:
Hannah L. F. Swa, Manikandan Lakshmanan, Jianxiang Chen, Kam M. Hui, Yan Shan Ong, Li Shen Loo, Wanjin Hong, Semih Can Akıncılar, Jayantha Gunaratne, Vinay Tergaonkar, Sayan Chakraborty, Xiaoqian Zhang
Publikováno v:
Nature Communications
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths globally. The identity and role of cell surface molecules driving complex biological events leading to HCC progression are poorly understood, hence representing majo
Annexin 1 (ANXA1), the first characterized member of the annexin superfamily, is known to bind or annex to cellular membranes in a calcium-dependent manner. Besides mediating inflammation, ANXA1 has also been reported to be involved in important phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1030aa6d513f74569d4892e7c8edc14d
https://europepmc.org/articles/PMC3412969/
https://europepmc.org/articles/PMC3412969/
Autor:
Hannah L. F. Swa, Kelly A. Hogue, Walter Blackstock, Jayantha Gunaratne, Koichi Okumura, Emma Sanford, Loke Meng Wong, Mei Xian Goh, Fen Yee Lee
Publikováno v:
The Journal of biological chemistry. 286(20)
The tumor suppressor PTEN (phosphatase and tensin homologue) negatively regulates the PI3K pathway through its lipid phosphatase activity and is one of the most commonly lost tumor suppressors in human cancers. Though the tumor suppressive function i