Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hannah L Stewart"'
Autor:
Roxanne Vandermause, Rachel Kryah, Julie Bertram, Hannah L Stewart, Nil Ean, Steven Bruce, Adam W Carrico, Julie A Mannarino, Robert H Paul
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 3, p e0002941 (2024)
Qualitative research approaches were used to launch an international research collaboration between the U. S. and Cambodia. Cambodian officials requested assistance in learning qualitative approaches to complement the research skills of Cambodian men
Externí odkaz:
https://doaj.org/article/0f96016945834102ba5edffc1c319b21
Autor:
Mélanie Uguen, Gemma Davison, Lukas J. Sprenger, James H. Hunter, Mathew P. Martin, Shannon Turberville, Jessica E. Watt, Bernard T. Golding, Martin E. M. Noble, Hannah L. Stewart, Michael J. Waring
Publikováno v:
Journal of Medicinal Chemistry. 65:11322-11339
High-throughput screening provides one of the most common ways of finding hit compounds. Lead-like libraries, in particular, provide hits with compatible functional groups and vectors for structural elaboration and physical properties suitable for op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6256166e5479fe951e145b5d73e9a32f
https://doi.org/10.1021/acs.jmedchem.2c00897
https://doi.org/10.1021/acs.jmedchem.2c00897
Autor:
Menton M. Deweese, Kimberly N. Claiborne, Jennifer Ng, Danika D. Dirba, Hannah L. Stewart, Susan M. Schembre, Francesco Versace
Publikováno v:
MethodsX, Vol 2, Iss C, Pp 446-457 (2015)
Neurobiological models of obesity postulate that obese individuals have difficulty regulating food intake partly because they attribute excessive salience to stimuli signaling food availability. Typically, human studies that investigate the relations
Externí odkaz:
https://doaj.org/article/5074f233945b43c4b51ee22d424f31c8
Autor:
Lan Z. Wang, Miller Duncan Charles, Bernard T. Golding, Ian Hickson, Martin E.M. Noble, Celine Cano, Suzannah J. Harnor, Michael J. Waring, Harry J Shrives, Shaimaa Khalifa, Jane Totobenazara, Stephen J. Hobson, Elaine Willmore, Hannah L Stewart, Mathew P. Martin, Susan J. Tudhope, Huw D. Thomas, Islam Al-Khawaldeh, Claire E. Jennings, João V de Souza, Max J. Temple, Jane A. Endicott, Cinzia Bordoni, Honorine Lebraud, Agnieszka K. Bronowska, Ian R. Hardcastle, Amy B. Heptinstall, Stephen R. Wedge, Christine Basmadjian, Gregory G Aldred, Julie A. Tucker, Mohammed J Al Yasiri
Publikováno v:
Journal of Medicinal Chemistry. 64:10001-10018
NF-κB-inducing kinase (NIK) is a key enzyme in the noncanonical NF-κB pathway, of interest in the treatment of a variety of diseases including cancer. Validation of NIK as a drug target requires potent and selective inhibitors. The protein contains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56300566066f33b5e78d20a96b537040
https://doi.org/10.1021/acs.jmedchem.0c01249
https://doi.org/10.1021/acs.jmedchem.0c01249
A comprehensive review of the brown macroalgal genus Turbinaria JV Lamouroux (Fucales, Sargassaceae)
Publikováno v:
Journal of Applied Phycology
Journal of Applied Phycology, Springer Verlag, 2020, 32 (5), pp.2743-2760. ⟨10.1007/s10811-020-02188-z⟩
Journal of Applied Phycology, Springer Verlag, 2020, 32 (5), pp.2743-2760. ⟨10.1007/s10811-020-02188-z⟩
WOS:000546220200003; International audience; Turbinaria J.V. Lamouroux is a genus of brown algae of the family Sargassaceae (Fucales, Phaeophyceae) found throughout the tropics, subtropics, and occasionally in temperate marine regions. There are curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f600eb052e8bb3a5dca48cf8657e3ee
https://hal.archives-ouvertes.fr/hal-03032155
https://hal.archives-ouvertes.fr/hal-03032155
Autor:
Hannah F. Sore, Julien J. Freudenreich, Andrew D. Bond, Hannah L. Stewart, David A. Russell, David R. Spring
Publikováno v:
Organic & Biomolecular Chemistry. 16:6395-6398
We describe semi-syntheses of the 11-hydroxyrotenoids sumatrol (1) and villosinol (2), starting from rotenone (5), using an oxime-directed C11-H functionalisation approach. Thus, rotenone (5) was converted into rotenone oxime (6), which gave dimeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c2aeffc48433a3b0ed999126fad240
https://doi.org/10.1039/c8ob01919c
https://doi.org/10.1039/c8ob01919c
Autor:
Warren R. J. D. Galloway, Hannah L. Stewart, Hannah F. Sore, David R. Spring, Joe J. Ciardiello
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:2825-2843
Recent years have witnessed a global decline in the productivity and advancement of the pharmaceutical industry. A major contributing factor to this is the downturn in drug discovery successes. This can be attributed to the lack of structural (partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e0115f1a6e27106b3cbc2ea055f17d
https://doi.org/10.1016/j.bmc.2017.02.060
https://doi.org/10.1016/j.bmc.2017.02.060
Autor:
Kim T. Mortensen, Thomas A. King, Hannah L. Stewart, David R. Spring, Andrew J. P. North, Hannah F. Sore
Publikováno v:
European Journal of Organic Chemistry
In recent years the pharmaceutical industry has benefited from the advances made in fragment-based drug discovery (FBDD) with more than 30 fragment-derived drugs currently marketed or progressing through clinical trials. The success of fragment-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02824b02e58fd1f168f32c5f7bf7b9e4
https://pubmed.ncbi.nlm.nih.gov/31598091
https://pubmed.ncbi.nlm.nih.gov/31598091
Autor:
Hannah L. Stewart, Sarah L. Kidd, Warren R. J. D. Galloway, Sean Bartlett, David R. Spring, Thomas J. Osberger, Hannah F. Sore, Natalia Mateu, Andrew J. P. North
Research into the applications of small molecules has proven to be a fruitful field for enabling both the investigation and understanding of biological systems and, thus, also forms the basis of many modern medicinal investigations. Indeed, the scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1267546f1a162c407a8a17752b176c2
https://doi.org/10.1039/9781788012805-00008
https://doi.org/10.1039/9781788012805-00008
Publikováno v:
Marine Ecology Progress Series. 532:197-211
Understanding how habitat complexity shapes fish communities is necessary to predict the consequences of future habitat change. On temperate rocky reefs, the presence and characteristics of canopy-forming kelps and the architectural complexity, or ru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd166af3d05d48020f703802eb7c22b4
https://doi.org/10.3354/meps11330
https://doi.org/10.3354/meps11330