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pro vyhledávání: '"Hannah L Elwell"'
Autor:
Jessica C Garbern, Qiang Li, Ren Liu, Estela Mancheno Juncosa, Zuwan Lin, Hannah L Elwell, Junya Aoyama, Sokol K Morgan, Jia Liu, Richard T Lee
Publikováno v:
Circulation. 144
Clinical translation of stem cell therapies for heart disease is limited by a risk of potentially life-threatening ventricular arrhythmias seen following cardiomyocyte delivery in large animal models. Enhancing cardiomyocyte maturation may reduce thi
Autor:
Jessica C Garbern, Hannah L Elwell, Estela Mancheno Juncosa, Daphne van den Berg, Morgan K Sokol, Richard T Lee
Publikováno v:
Circulation. 144
Directed differentiation of human pluripotent stem cells (PSC) into cardiomyocytes via manipulation of Wnt signaling leads to generation of immature cardiomyocytes, more closely resembling a fetal state. It has become increasingly apparent that metab