Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hannah K. Graham"'
Autor:
Jaime Belkind-Gerson, Hannah K. Graham, Justin Reynolds, Ryo Hotta, Nandor Nagy, Lily Cheng, Michal Kamionek, Hai Ning Shi, Carol M. Aherne, Allan M. Goldstein
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Mechanisms mediating adult enteric neurogenesis are largely unknown. Using inflammation-associated neurogenesis models and a transgenic approach, we aimed to understand the cell-source for new neurons in infectious and inflammatory colitis.
Externí odkaz:
https://doaj.org/article/98a0aa1a66ae46da8336099aaa713215
Autor:
Allan M. Goldstein, Ryo Hotta, Emoke Szocs, Nandor Nagy, Rhian Stavely, Adam Soos, Tamas Kovacs, Hannah K. Graham, Viktoria Halasy
Publikováno v:
Development
The enteric nervous system (ENS), which is derived from enteric neural crest cells (ENCCs), represents the neuronal innervation of the intestine. Compromised ENCC migration can lead to Hirschsprung disease, which is characterized by an aganglionic di
Autor:
Anne C. Hart, Hannah K Graham, Patrick J O'Hern, Altar Sorkaç, Michael A DiIorio, Saba N. Baskoylu
Publikováno v:
G3: Genes|Genomes|Genetics
The role of Notch signaling in cell-fate decisions has been studied extensively; however, this pathway is also active in adult tissues, including the nervous system. Notch signaling modulates a wide range of behaviors and processes of the nervous sys
Autor:
Allan M. Goldstein, Jaime Belkind-Gerson, Lily S. Cheng, Ryo Hotta, Hannah K. Graham, Nandor Nagy
Publikováno v:
Pediatric research
Cheng, LS; Hotta, R; Graham, HK; Belkind-Gerson, J; Nagy, N; & Goldstein, AM. (2017). Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments. Pediatric Research, 81(5), 838-846. doi: 10.1038/pr.2017.4. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1hf68923
Cheng, LS; Hotta, R; Graham, HK; Belkind-Gerson, J; Nagy, N; & Goldstein, AM. (2017). Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments. Pediatric Research, 81(5), 838-846. doi: 10.1038/pr.2017.4. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1hf68923
© 2017 International Pediatric Research Foundation, Inc. Background:Enteric neural stem/progenitor cells (ENSCs) offer an innovative approach to treating Hirschsprung disease (HSCR) and other enteric neuropathies. However, postnatal-derived human EN
Autor:
Xin Duan, Hannah K. Graham
Publikováno v:
Wiley Interdiscip Rev Dev Biol
The central nervous system (CNS) is composed of precisely assembled circuits which support a variety of physiological functions and behaviors. These circuits include multiple subtypes of neurons with unique morphologies, electrical properties, and mo
Autor:
Ryo Hotta, Jaime Belkind-Gerson, Lily S. Cheng, Allan M. Goldstein, Michal Kamionek, Nandor Nagy, Hannah K. Graham, Justin S. Reynolds, Hai Ning Shi, Carol M. Aherne
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Mechanisms mediating adult enteric neurogenesis are largely unknown. Using inflammation-associated neurogenesis models and a transgenic approach, we aimed to understand the cell-source for new neurons in infectious and inflammatory colitis. Dextran s
Publikováno v:
Journal of anatomy. 230(4)
The development of the enteric nervous system (ENS) and intestinal smooth muscle occurs in a spatially and temporally correlated manner, but how they influence each other is unknown. In the developing midgut of the chick embryo, we find that smooth m
Recent evidence suggests that patients with Hirschsprung disease (HD) have abnormal neurotransmitter expression in the ganglionated proximal colon. These alterations may cause persistent bowel dysfunction even after pullthrough surgery. We sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f570da4b21a6c96a1fd80758e0dee7
https://europepmc.org/articles/PMC5065396/
https://europepmc.org/articles/PMC5065396/
Autor:
Allan M. Goldstein, Ryo Hotta, Lily S. Cheng, Alfonso Carreon-Rodriguez, Wei Hua Pan, Nandor Nagy, Hannah K. Graham
Publikováno v:
The Journal of surgical research. 206(2)
Enteric neurospheres derived from postnatal intestine represent a promising avenue for cell replacement therapy to treat Hirschsprung disease and other neurointestinal diseases. We describe a simple method to improve the neuronal yield of spontaneous
Autor:
Weikang Pan, Jaime Belkind-Gerson, Hannah K. Graham, Nandor Nagy, Lily S. Cheng, Allan M. Goldstein, Ryo Hotta
Background Transplanting autologous patient-derived enteric neuronal stem/progenitor cells (ENSCs) is an innovative approach to replacing missing enteric neurons in patients with Hirschsprung disease (HSCR). Using autologous cells eliminates immunolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81b460496eb12477d4a1241805cdae8
https://europepmc.org/articles/PMC4808355/
https://europepmc.org/articles/PMC4808355/