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pro vyhledávání: '"Hannah K. Daly"'
Autor:
Supriya Shah, Karen E. Knudsen, Yehia Daaka, Joanne Boldison, Sonia Godoy-Tundidor, Jae Kim, Siobhan Webb, Janet K. Hess-Wilson, Hannah K. Daly
Publikováno v:
Molecular Cancer Research. 6:1507-1520
Therapy resistance represents a major clinical challenge in disseminated prostate cancer for which only palliative treatment is available. One phenotype of therapy-resistant tumors is the expression of somatic, gain-of-function mutations of the andro
Autor:
Clay E.S. Comstock, Yuet-Kin Leung, Siobhan Webb, Maureen A. Sartor, Janet K. Hess-Wilson, Shuk-Mei Ho, Hannah K. Daly, Joanne Boldison, Karen E. Knudsen
Publikováno v:
Environmental Health Perspectives
Accruing evidence indicates that exposure to environmental compounds that affect the function of the endocrine system may adversely impact human health. These substances deemed “endocrine disrupting compounds,” or EDCs, are agents that disrupt or
Autor:
Karen E. Knudsen, William A. Zagorski, Christopher P. Montville, Janet K. Hess-Wilson, Hannah K. Daly
Publikováno v:
Cancer Research. 66:11998-12008
Prostate cancer cells are dependent on androgen for growth and survival; as such, inhibition of androgen receptor (AR) activity is the first line of intervention for disseminated disease. Recently, specific cytotoxic agents have been shown to extend