Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Hannah K Palliser"'
Publikováno v:
Brain and Behavior, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Preterm birth is associated with brain injury and long‐term behavioral abnormalities, for which there are limited prevention options. When born preterm, infants prematurely lose placental neurosteroid (allopregnanolone) support.
Externí odkaz:
https://doaj.org/article/eb59e0232e1c4d4a81285f01def0385f
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148226 (2016)
The placental glucocorticoid receptor (GR) is central to glucocorticoid signalling and for mediating steroid effects on pathways associated with fetal growth and lung maturation but the GR has not been examined in the guinea pig placenta even though
Externí odkaz:
https://doaj.org/article/24e5464dcb3b4d2fa8116e010f053fbd
Autor:
Rebecca M Dyson, Hannah K Palliser, Joanna L Latter, Megan A Kelly, Grazyna Chwatko, Rafal Glowacki, Ian M R Wright
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121621 (2015)
Hydrogen sulphide (H2S), nitric oxide (NO), and carbon monoxide (CO) are involved in transitional microvascular tone dysregulation in the preterm infant; however there is conflicting evidence on the interaction of these gasotransmitters, and their ov
Externí odkaz:
https://doaj.org/article/44f54b12bcd048fe89c1b556e076b8af
Autor:
Rebecca M Dyson, Hannah K Palliser, Joanna L Latter, Grazyna Chwatko, Rafal Glowacki, Ian M R Wright
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105085 (2014)
Excessive vasodilatation during the perinatal period is associated with cardiorespiratory instability in preterm neonates. Little evidence of the mechanisms controlling microvascular tone during circulatory transition exists. We hypothesised that hyd
Externí odkaz:
https://doaj.org/article/911e795bb2294afcba8383217ca43cf6
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Preterm birth is known to cause impaired cerebellar development, and this is associated with the development of neurobehavioral disorders. This review aims to identify the mechanisms through which preterm birth impairs cerebellar development and cons
Externí odkaz:
https://doaj.org/article/2a64ea2602804c018ed7a8c20c0f7bd1
Autor:
Roisin A. Moloney, Carlton L. Pavy, Richard G. S. Kahl, Hannah K. Palliser, Jon J. Hirst, Julia C. Shaw
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
Primary cell culture is a technique that is widely used in neuroscience research to investigate mechanisms that underlie pathologies at a cellular level. Typically, mouse or rat tissue is used for this process; however, altricial rodent species have
Externí odkaz:
https://doaj.org/article/c6738e483d1641448a1cafbefebe3c2d
Autor:
Gabrielle K. Crombie, Hannah K. Palliser, Julia C Shaw, Bethany A Hanley, Roisin A Moloney, Jonathan J. Hirst
Publikováno v:
Developmental Neuroscience.
Background: Disruptions to neurodevelopment is known to be linked to behavioural disorders in childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter inhibitory GABAergic pathways and critical myelination processes
Autor:
Julia C. Shaw, Rebecca M. Dyson, Hannah K. Palliser, Ryan P. Sixtus, Heather Barnes, Carlton L. Pavy, Gabrielle K. Crombie, Mary J. Berry, Jonathan J. Hirst
Publikováno v:
Frontiers in physiology. 13
Background: Preterm birth can lead to brain injury and currently there are no targeted therapies to promote postnatal brain development and protect these vulnerable neonates. We have previously shown that the neurosteroid-analogue ganaxolone promotes
Autor:
Gabrielle K, Crombie, Hannah K, Palliser, Julia C, Shaw, Deborah M, Hodgson, David W, Walker, Jonathan J, Hirst
Publikováno v:
Psychoneuroendocrinology. 139:105705
A correct balance of activity of the GABA and glutamate systems is vital for optimal neurodevelopment and general CNS function, and the dysregulation of this balance has been implicated in a number of neurological conditions. Maternal exposure to str
Autor:
Jonathan J. Hirst, Julia C. Shaw, David W. Walker, Hannah K. Palliser, Gabrielle K. Crombie, Deborah M. Hodgson
Publikováno v:
Psychoneuroendocrinology. 124
Background Chronic psychosocial stress during pregnancy and/or after birth, and the associated elevation in cortisol, is linked with the onset of behavioural disorders in childhood. Previously, prenatal stress has been shown to reduce neurosteroid pa