Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hannah K Jaeger"'
Autor:
Prabha Shrestha, David A Davis, Hannah K Jaeger, Alexandra Stream, Ashley I Aisabor, Robert Yarchoan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009091 (2021)
Pomalidomide (Pom) is an immunomodulatory drug that has efficacy against Kaposi's sarcoma, a tumor caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Pom also induces direct cytotoxicity in primary effusion lymphoma (PEL), a B-cell malignancy
Externí odkaz:
https://doaj.org/article/b3d30c82e82642ab96622ea46ba2b8f4
Autor:
David A. Davis, Haydar Bulut, Prabha Shrestha, Amulya Yaparla, Hannah K. Jaeger, Shin-ichiro Hattori, Paul T. Wingfield, John J. Mieyal, Hiroaki Mitsuya, Robert Yarchoan
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication. The main protease (Mpro), encoded as part of two polyproteins, pp1a an
Externí odkaz:
https://doaj.org/article/125d60db37064da6acb66a5868cdb04c
Autor:
Haydar Bulut, John J. Mieyal, Hiroaki Mitsuya, Hannah K. Jaeger, David A. Davis, Robert Yarchoan, Paul T. Wingfield, Prabha Shrestha, Amulya Yaparla, Shin-ichiro Hattori
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 2
mBio
mBio, Vol 12, Iss 4 (2021)
article-version (status) pre
article-version (number) 2
mBio
mBio, Vol 12, Iss 4 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication. The main protease (Mpro), encoded as part of two polyproteins, pp1a and pp1ab,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e735e8d470cc6d0008b7fff2320b047e
https://doi.org/10.1101/2021.04.09.439169
https://doi.org/10.1101/2021.04.09.439169
Autor:
Natacha Teissier, Deborah Duricka, Elizabeth M. Keithley, Elizabeth A. Fortunato, Emmerentia Marx, Man I Kuan, Liliana Gabrielli, Hannah K Jaeger, Holger Hannemann, Maria Paola Bonasoni, John M. O'Dowd, Onesmo B. Balemba
Publikováno v:
J Virol
In 2000, we reported that human cytomegalovirus (HCMV) induced specific damage on chromosome 1. The capacity of the virus to induce DNA breaks indicated potent interaction between viral proteins and these loci. We have fine mapped the 1q42 breaksite.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcc546670777a0590d59acda176a65f
https://doi.org/10.1128/jvi.01506-20
https://doi.org/10.1128/jvi.01506-20
Autor:
Rebecca M Brown, Elizabeth A. Fortunato, Onesmo B. Balemba, Pranav S J B Rana, Hannah K Jaeger, John M. O'Dowd
Publikováno v:
Journal of Virology. 93
Congenital human cytomegalovirus (HCMV) infection causes a broad spectrum of central and peripheral nervous system disorders, ranging from microcephaly to hearing loss. These ramifications mandate the study of virus-host interactions in neural cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422f182a6dc7ac95dfa5cb05336bbab2
https://doi.org/10.1128/jvi.00957-19
https://doi.org/10.1128/jvi.00957-19
Autor:
Ashley I. Aisabor, Prabha Shrestha, David A. Davis, Hannah K. Jaeger, Alexandra Stream, Robert Yarchoan
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 1, p e1009091 (2021)
PLoS Pathogens, Vol 17, Iss 1, p e1009091 (2021)
Pomalidomide (Pom) is an immunomodulatory drug that has efficacy against Kaposi’s sarcoma, a tumor caused by Kaposi’s sarcoma-associated herpesvirus (KSHV). Pom also induces direct cytotoxicity in primary effusion lymphoma (PEL), a B-cell maligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209d36ee82dbcae0bb2a51e5ad4a4fb9
https://doi.org/10.1371/journal.ppat.1009091
https://doi.org/10.1371/journal.ppat.1009091
Autor:
Hannah K. Jaeger, David A. Davis, Ashwin Nair, Prabha Shrestha, Alexandra Stream, Amulya Yaparla, Robert Yarchoan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Epstein-Barr virus (EBV) downregulates immune surface markers to avoid immune recognition. Pomalidomide (Pom) was previously shown to increase immune surface marker expression in EBV-infected tumor cells. We explored the mechanism by which P
Externí odkaz:
https://doaj.org/article/771ce4b7f791411a9936e4e4d4d179d5