Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hannah Johns"'
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1608-1615 (2023)
Abstract Interventional clinical trials in epilepsy are typically designed and powered to detect a change in seizure frequency as the primary endpoint, with little consideration given to other benefits or harms of the therapy, or impacts on common ep
Externí odkaz:
https://doaj.org/article/84815a6812a54099b6d58a6ba1948d88
Autor:
Venesha Rethnam, Kathryn S. Hayward, Hannah Johns, Lilian B. Carvalho, Leonid Churilov, Julie Bernhardt
Publikováno v:
Frontiers in Stroke, Vol 2 (2023)
IntroductionMany stroke guidelines recommend against starting intensive out-of-bed activity (mobilization) within 24 h post-stroke. Few guidelines address care after the first 24–48 h, and little information is provided about how early mobilization
Externí odkaz:
https://doaj.org/article/9a86572779f64a25996a68119325ad8c
Autor:
Lucy Vivash, Dennis Velakoulis, Patrick Carney, Patrick Kwan, Leonid Churilov, Terence J O’Brien, Christopher M Hovens, Nicholas Lawn, Piero Perucca, Sandy R Shultz, John-Paul Nicolo, Charles Malpas, Manori Wijayath, David Reutens, Hannah Johns, Sara MacPhail, Pablo Casillas-Espinosa, Chris Tailby, Lisa Gillinder
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Epilepsy is one of the most common neurological conditions worldwide. Despite many antiseizure medications (ASMs) being available, up to one-third of patients do not achieve seizure control. Preclinical studies have shown treatment with
Externí odkaz:
https://doaj.org/article/3fd64e9e8e8b4ff9b7e3d63e337655c5
Autor:
Amrou Sarraj, Ameer E. Hassan, Michael G. Abraham, Santiago Ortega-Gutierrez, Scott E. Kasner, M. Shazam Hussain, Michael Chen, Spiros Blackburn, Clark W. Sitton, Leonid Churilov, Sophia Sundararajan, Yin C. Hu, Nabeel A. Herial, Pascal Jabbour, Daniel Gibson, Adam N. Wallace, Juan F. Arenillas, Jenny P. Tsai, Ronald F. Budzik, William J. Hicks, Osman Kozak, Bernard Yan, Dennis J. Cordato, Nathan W. Manning, Mark W. Parsons, Ricardo A. Hanel, Amin N. Aghaebrahim, Teddy Y. Wu, Pere Cardona-Portela, Natalia Pérez de la Ossa, Joanna D. Schaafsma, Jordi Blasco, Navdeep Sangha, Steven Warach, Chirag D. Gandhi, Timothy J. Kleinig, Daniel Sahlein, Lucas Elijovich, Wondwossen Tekle, Edgar A. Samaniego, Laith Maali, M. Ammar Abdulrazzak, Marios N. Psychogios, Ashfaq Shuaib, Deep K. Pujara, Faris Shaker, Hannah Johns, Gagan Sharma, Vignan Yogendrakumar, Felix C. Ng, Mohammad H. Rahbar, Chunyan Cai, Philip Lavori, Scott Hamilton, Thanh Nguyen, Johanna T. Fifi, Stephen Davis, Lawrence Wechsler, Vitor M. Pereira, Maarten G. Lansberg, Michael D. Hill, James C. Grotta, Marc Ribo, Bruce C. Campbell, Gregory W. Albers
Publikováno v:
New England Journal of Medicine. 388:1259-1271
Publikováno v:
Statistical Methods in Medical Research. 32:609-625
The win ratio is a novel approach for handling complex patient outcomes that have seen considerable interest in the medical statistics literature, and operates by considering all-to-all pairwise statements of preference on outcomes. Recent extensions
Autor:
Carlos, Garcia-Esperon, Andrew, Bivard, Hannah, Johns, Chushuang, Chen, Leonid, Churilov, Longting, Lin, Kenneth, Butcher, Timothy J, Kleinig, Philip M C, Choi, Xin, Cheng, Qiang, Dong, Richard I, Aviv, Ferdinand, Miteff, Neil J, Spratt, Christopher R, Levi, Mark W, Parsons
Publikováno v:
Neurology. 99:e1345-e1355
Background and ObjectivesEndovascular thrombectomy (EVT) is effective for patients with large vessel occlusion (LVO) stroke with smaller volumes of CT perfusion (CTP)-defined ischemic core. However, the benefit of EVT is unclear in those with a core
Publikováno v:
Stroke. 53:3032-3034
Autor:
Peter Wotherspoon, Hannah Johnston, David J. Hardy, Rachel Holyfield, Soi Bui, Giedrė Ratkevičiūtė, Pooja Sridhar, Jonathan Colburn, Charlotte B. Wilson, Adam Colyer, Benjamin F. Cooper, Jack A. Bryant, Gareth W. Hughes, Phillip J. Stansfeld, Julien R. C. Bergeron, Timothy J. Knowles
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The Maintenance of Lipid Asymmetry (Mla) pathway is a multicomponent system found in all gram-negative bacteria that contributes to virulence, vesicle blebbing and preservation of the outer membrane barrier function. It acts by removing ecto
Externí odkaz:
https://doaj.org/article/b7c3efd6199f407a8b00be9ac32695d5
Publikováno v:
Statistical Methods in Medical Research. 30:2085-2104
Predicting patient outcomes based on patient characteristics and care processes is a common task in medical research. Such predictive features are often multifaceted and complex, and are usually simplified into one or more scalar variables to facilit
Autor:
Julie, Bernhardt, Leonid, Churilov, Helen, Dewey, Geoffrey, Donnan, Fiona, Ellery, Coralie Kym, English, Lan, Gao, Kathryn S, Hayward, Frances, Horgan, Bent, Indredavik, Hannah, Johns, Peter, Langhorne, Richard, Lindley, Sheila, Martins, Katijjahbe, Mohd Ali, Sandy, Middleton, Marj, Moodie, Jeyaraj Durai, Pandian, Brooke, Parsons, Tom, Robinson, Velandai, Srikanth, Vincent, Thijs
Publikováno v:
International Journal of Stroke. :174749302211422
Rationale: The evidence base for acute post-stroke rehabilitation is inadequate and global guideline recommendations vary. Aim: To define optimal early mobility intervention regimens for ischemic stroke patients of mild and moderate severity. Hypothe