Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hannah J, Whittington"'
Autor:
Sevasti Zervou, Debra J. McAndrew, Hannah J. Whittington, Hannah A. Lake, Kyung Chan Park, Kuan Minn Cha, Philip J. Ostrowski, Thomas R. Eykyn, Jürgen E. Schneider, Stefan Neubauer, Craig A. Lygate
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
AimsAdenylate kinase 1 (AK1) catalyses the reaction 2ADP ↔ ATP + AMP, extracting extra energy under metabolic stress and promoting energetic homeostasis. We hypothesised that increased AK1 activity would have negligible effects at rest, but protect
Externí odkaz:
https://doaj.org/article/4987ce7164ec4b948b413bb6efbed548
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S8. Hydrophilic metabolites detection and identification performed by LC/MS QTOF nanoflow using AMRT comparison.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0a54f3dc60141a5e0f82db99f8851b
https://doi.org/10.1158/1541-7786.22515489.v1
https://doi.org/10.1158/1541-7786.22515489.v1
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S3. HIF1α and hypoxia-dependent effects on transcription and protein levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d37bd4b9cbd85ee8251787d7b3404c
https://doi.org/10.1158/1541-7786.22515507
https://doi.org/10.1158/1541-7786.22515507
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
Supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c64d0ff63bdf85ae6f0c1526a1b4439
https://doi.org/10.1158/1541-7786.22515486.v1
https://doi.org/10.1158/1541-7786.22515486.v1
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S7. WTN, KON, WTH, and KOH HCT116 cell proliferation after 5 days in two O2 conditions, 21% and 1% for cells knocked down for GTR3, GTR14, and HIF2α.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6b37322074a771d53a39cf956e9445
https://doi.org/10.1158/1541-7786.22515492
https://doi.org/10.1158/1541-7786.22515492
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S1. Blocking O-GlcNAcylation in vivo by inducing shOGT or alloxan treatment qualitatively reduces EZH2 immunoreactivity after irradiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af406913e6eafebcfe6bc40d9340bf70
https://doi.org/10.1158/1541-7786.22515516.v1
https://doi.org/10.1158/1541-7786.22515516.v1
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S6. Phosphocreatine/Creatine ratio per cell in WTN, KON, WTH, and KOH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e8c579e949e728c2201e45471a2e67
https://doi.org/10.1158/1541-7786.22515495
https://doi.org/10.1158/1541-7786.22515495
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S8. WTN, KON, WTH, and KOH HCT116 cell proliferation after 5 days in two O2 conditions,21% and 1% for cells knocked down for GTR3, GTR14 , and HIF2α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27425d97838807101220d8e938f65a48
https://doi.org/10.1158/1541-7786.22515519.v1
https://doi.org/10.1158/1541-7786.22515519.v1
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
S4. Hypoxic regulation of glucose transporters and creatine kinases validation by PCR and western blot analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9b931187f0540b863586f6c69f5f13
https://doi.org/10.1158/1541-7786.22515504.v1
https://doi.org/10.1158/1541-7786.22515504.v1
Autor:
Adrian L. Harris, Benedikt M. Kessler, Craig A. Lygate, Sevasti Zervou, Hannah A. Lake, Hannah J. Whittington, Oscar Yanes, Miguel Rodriguez, Dilair Baban, Francesca M. Buffa, Syed Haider, Esther Bridges, Alan McIntyre, Martin Frejno, Roman Fischer, Katharina Feldinger, Tomoyoshi Soga, Patrick K. Albers, Christos E. Zois, Matteo Morotti, Alessandro Valli
Hypoxia-inducible factor 1α is a key regulator of the hypoxia response in normal and cancer tissues. It is well recognized to regulate glycolysis and is a target for therapy. However, how tumor cells adapt to grow in the absence of HIF1α is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6082bae762bf6fa39db8d16b85ec6a15
https://doi.org/10.1158/1541-7786.c.6541104
https://doi.org/10.1158/1541-7786.c.6541104