Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hannah I. Hoffman"'
Autor:
Jimmy A. Guo, Mohammed Alshalalfa, Daniel Y. Kim, Hannah I. Hoffman, Carina Shiau, Jennifer Su, William L. Hwang, Brandon A. Mahal
Publikováno v:
Cancer Genetics. :1-4
Immune checkpoint blockade (ICB) has shown immense promise for treating patients with various cancer types, but its effectiveness relies on our ability to identify likely responders. Here, we examined the association between mutations in 25 core DNA
Autor:
William L. Hwang, Mari Mino-Kenudson, Theodore S. Hong, Andrew J. Aguirre, Tyler Jacks, Carlos Fernandez-del Castillo, Jay S. Loeffler, Jennifer Y. Wo, Andrzej Niemierko, Mohammed Alshalalfa, Brandon A. Mahal, Daniel Zhao, Stephanie W. Cheng, Daniel W. Kim, Daniel Y. Kim, Peter G. Hwang, Peter Chen, Stuti G. Shroff, Hannah I. Hoffman, Jimmy A. Guo
Purpose:Perineural invasion (PNI) is associated with aggressive tumor behavior, recurrence, and metastasis, and can influence the administration of adjuvant treatment. However, standard histopathologic examination has limited sensitivity in detecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5178497bed8f422c0335e0d0f6d1865e
https://doi.org/10.1158/1078-0432.c.6529883
https://doi.org/10.1158/1078-0432.c.6529883
Autor:
William L. Hwang, Mari Mino-Kenudson, Theodore S. Hong, Andrew J. Aguirre, Tyler Jacks, Carlos Fernandez-del Castillo, Jay S. Loeffler, Jennifer Y. Wo, Andrzej Niemierko, Mohammed Alshalalfa, Brandon A. Mahal, Daniel Zhao, Stephanie W. Cheng, Daniel W. Kim, Daniel Y. Kim, Peter G. Hwang, Peter Chen, Stuti G. Shroff, Hannah I. Hoffman, Jimmy A. Guo
Supplementary Data Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e947f42535ee23aaf0847682b7ec66
https://doi.org/10.1158/1078-0432.22478201.v1
https://doi.org/10.1158/1078-0432.22478201.v1
Autor:
William L. Hwang, Mari Mino-Kenudson, Theodore S. Hong, Andrew J. Aguirre, Tyler Jacks, Carlos Fernandez-del Castillo, Jay S. Loeffler, Jennifer Y. Wo, Andrzej Niemierko, Mohammed Alshalalfa, Brandon A. Mahal, Daniel Zhao, Stephanie W. Cheng, Daniel W. Kim, Daniel Y. Kim, Peter G. Hwang, Peter Chen, Stuti G. Shroff, Hannah I. Hoffman, Jimmy A. Guo
Supplementary Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c95b455516b5fb12e82d3aaec022fcf
https://doi.org/10.1158/1078-0432.22478198.v1
https://doi.org/10.1158/1078-0432.22478198.v1
Autor:
William L. Hwang, Mari Mino-Kenudson, Theodore S. Hong, Andrew J. Aguirre, Tyler Jacks, Carlos Fernandez-del Castillo, Jay S. Loeffler, Jennifer Y. Wo, Andrzej Niemierko, Mohammed Alshalalfa, Brandon A. Mahal, Daniel Zhao, Stephanie W. Cheng, Daniel W. Kim, Daniel Y. Kim, Peter G. Hwang, Peter Chen, Stuti G. Shroff, Hannah I. Hoffman, Jimmy A. Guo
Supplementary Figure S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9db04297b5a30cb563bb4c2afb788a
https://doi.org/10.1158/1078-0432.22478195.v1
https://doi.org/10.1158/1078-0432.22478195.v1
Autor:
William L. Hwang, Mari Mino-Kenudson, Theodore S. Hong, Andrew J. Aguirre, Tyler Jacks, Carlos Fernandez-del Castillo, Jay S. Loeffler, Jennifer Y. Wo, Andrzej Niemierko, Mohammed Alshalalfa, Brandon A. Mahal, Daniel Zhao, Stephanie W. Cheng, Daniel W. Kim, Daniel Y. Kim, Peter G. Hwang, Peter Chen, Stuti G. Shroff, Hannah I. Hoffman, Jimmy A. Guo
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820120fa22fb87df3a787568abf4cf6b
https://doi.org/10.1158/1078-0432.22478186.v1
https://doi.org/10.1158/1078-0432.22478186.v1
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Carina Shiau, Jennifer Su, Payman Yadollahpour, Jason W. Reeves, Youngmi Kim, Sean Kim, Mark Gregory, Prajan Divakar, Eric Miller, Michael Rhodes, Sarah Warren, Erroll Rueckert, Kit Fuhrman, Daniel R. Zollinger, Robin Fropf, Joseph M. Beechem, Arnav Mehta, Toni Delorey, Cristin McCabe, Jaimie L. Barth, Piotr Zelga, Cristina R. Ferrone, Motaz Qadan, Keith D. Lillemoe, Rakesh K. Jain, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Orit Rozenblatt-Rosen, Andrew J. Aguirre, Carlos Fernandez-Del Castillo, Andrew S. Liss, Mari Mino-Kenudson, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Cancer Research. 82:SY12-04
Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer mortality in the United States by 2030. Given that resistance to cytotoxic therapy is pervasive, there is a critical need to elucidate salient gene expressi
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Payman Yadollahpour, Jason W. Reeves, Rahul Mohan, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Orr Ashenberg, Samouil L. Farhi, Denis Schapiro, Prajan Divakar, Eric Miller, Daniel R. Zollinger, George Eng, Jason M. Schenkel, Jennifer Su, Carina Shiau, Patrick Yu, William A. Freed-Pastor, Domenic Abbondanza, Arnav Mehta, Joshua Gould, Conner Lambden, Caroline B. M. Porter, Alexander Tsankov, Danielle Dionne, Julia Waldman, Michael S. Cuoco, Lan Nguyen, Toni Delorey, Devan Phillips, Jaimie L. Barth, Marina Kem, Clifton Rodrigues, Debora Ciprani, Jorge Roldan, Piotr Zelga, Vjola Jorgji, Jonathan H. Chen, Zackery Ely, Daniel Zhao, Kit Fuhrman, Robin Fropf, Joseph M. Beechem, Jay S. Loeffler, David P. Ryan, Colin D. Weekes, Cristina R. Ferrone, Motaz Qadan, Martin J. Aryee, Rakesh K. Jain, Donna S. Neuberg, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Andrew J. Aguirre, Orit Rozenblatt-Rosen, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, Andrew S. Liss, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Nat Genet
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we construct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52fea7e3e72f452826d1f68df747811
https://europepmc.org/articles/PMC10290535/
https://europepmc.org/articles/PMC10290535/
Autor:
William L. Hwang, Jennifer Su, Carina Shiau, Peter L. Wang, Jimmy A. Guo, Nicole A. Lester, Jaimie L. Barth, Hannah I. Hoffman, Prajan Divakar, Jason W. Reeves, Eric Miller, Joseph M. Beechem, Andrew J. Aguirre, Lei Zheng, David T. Ting, Mari Mino-Kenudson, Tyler Jacks
Publikováno v:
Cancer Research. 83:2513-2513
Pancreatic ductal adenocarcinoma (PDAC) features abundant perineural invasion (PNI). Intra-tumoral nerves play critical roles in cancer initiation, progression, recurrence, treatment-resistance, metastasis, and mortality for many malignancies but the
Autor:
Diana D Shi, Jimmy A Guo, Hannah I Hoffman, Jennifer Su, Mari Mino-Kenudson, Jaimie L Barth, Jason M Schenkel, Jay S Loeffler, Helen A Shih, Theodore S Hong, Jennifer Y Wo, Andrew J Aguirre, Tyler Jacks, Lei Zheng, Patrick Y Wen, Timothy C Wang, William L Hwang
Publikováno v:
Lancet Oncol
With increasing attention on the essential roles of the tumour microenvironment in recent years, the nervous system has emerged as a novel and crucial facilitator of cancer growth. In this Review, we describe the foundational, translational, and clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f994935a5a186b670240b1520becb7c
https://europepmc.org/articles/PMC9516432/
https://europepmc.org/articles/PMC9516432/