Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats

Autor: Michael O’Hare, Gema Esquiva, Mary K. McGahon, Jose Manuel Romero Hombrebueno, Josy Augustine, Paul Canning, Kevin S. Edgar, Peter Barabas, Thomas Friedel, Patrizia Cincolà, Jennifer Henry, Katie Mayne, Hannah Ferrin, Alan W. Stitt, Timothy J. Lyons, Derek P. Brazil, David J. Grieve, J. Graham McGeown, Tim M. Curtis

Publikováno v: O'Hare, M, Esquiva, G, McGahon, M K, Hombrebueno, J M R, Augustine, J, Canning, P, Edgar, K S, Barabas, P, Friedel, T, Cincolà, P, Henry, J, Mayne, K, Ferrin, H, Stitt, A W, Lyons, T J, Brazil, D P, Grieve, D J, McGeown, J G & Curtis, T M 2022, ' Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats ', JCI insight, vol. 7, no. 18, e155128 . https://doi.org/10.1172/jci.insight.155128

Loss of retinal blood flow autoregulation is an early feature of diabetes that precedes the development of clinically recognizable diabetic retinopathy (DR). Retinal blood flow autoregulation is mediated by the myogenic response of the retinal arteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e026e1b17c412483c93ec37feda6a413
https://pubmed.ncbi.nlm.nih.gov/36134661