Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hannah F. Clarke"'
Autor:
Laith Alexander, Christian M. Wood, Philip L. R. Gaskin, Stephen J. Sawiak, Tim D. Fryer, Young T. Hong, Lauren McIver, Hannah F. Clarke, Angela C. Roberts
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Alexander et al. causally implicate over-activity in primate subgenual cingulate in affective and cardiovascular dysfunction relevant to anxiety and depression. Over-activation led to elevated activity in a stress-related network whilst decreasing ac
Externí odkaz:
https://doaj.org/article/c4882c5246f44a9f9ba8c63aa0cd943b
Autor:
Annabella Lear, Stuart N. Baker, Hannah F. Clarke, Angela C. Roberts, Michael C. Schmid, Wendy Jarrett
Publikováno v:
Current Research in Neurobiology, Vol 3, Iss , Pp 100049- (2022)
Studying higher brain function presents fundamental scientific challenges but has great potential for impactful translation to the clinic, supporting the needs of many patients suffering from conditions that relate to neuronal dysfunction. For many k
Externí odkaz:
https://doaj.org/article/97459ebe9e28456b9662c1d087edbd6a
Publikováno v:
Brain Sciences, Vol 9, Iss 6, p 129 (2019)
Subcallosal area 25 is one of the least understood regions of the anterior cingulate cortex, but activity in this area is emerging as a crucial correlate of mood and affective disorder symptomatology. The cortical and subcortical connectivity of area
Externí odkaz:
https://doaj.org/article/f266ba83deae475b926f80eb079a92cb
Autor:
Shaun K L Quah, Angela C. Roberts, Hannah F. Clarke, Gemma J Cockcroft, Andrea M. Santangelo, Nicole K. Horst, Kevin Mulvihill, Christian M Wood, Sufia S Rahman
Publikováno v:
Cerebral Cortex (New York, NY)
The midcingulate cortex (MCC) is associated with cognition and emotion regulation. Structural and correlational functional evidence suggests that rather than being homogenous, the MCC may have dissociable functions that can be mapped onto distinct su
Publikováno v:
Cerebral Cortex (New York, NY)
Affective disorders are associated with increased sensitivity to negative feedback that influences approach–avoidance decision making. Although neuroimaging studies of these disorders reveal dysregulation in primate cingulate areas 25 and 32 and th
Autor:
Lydia Oikonomidis, Christian M Wood, Angela C. Roberts, Lauren McIver, Kevin Mulvihill, Gemma J Cockcroft, Roohollah Massoudi, Zuzanna M Stawicka, Hannah F. Clarke, Nicole K. Horst, Shaun K L Quah
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 32(7)
Structural and functional abnormalities of the orbitofrontal cortex (OFC) have been implicated in affective disorders that manifest anxiety-related symptoms. However, research into the functions of primate OFC has predominantly focused on reward-orie
Autor:
Hannah F. Clarke, Laith Alexander, Angela C. Roberts, Stephen J. Sawiak, Lauren McIver, Philip L.R. Gaskin, Tim D. Fryer, Christian M Wood, Young T. Hong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Stress-related disorders such as depression and anxiety are characterized by enhanced negative emotion and physiological dysfunction. Whilst elevated activity within area 25 of the subgenual anterior cingulate cortex (sgACC/25) has been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eba638c8db9fb12ad300e77b8d339eb
Autor:
Angela C. Roberts, Hannah F. Clarke
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(52)
The ventromedial prefrontal cortex (vmPFC) is consistently implicated in the cognitive and emotional symptoms of many psychiatric disorders, but the causal mechanisms of its involvement remain unknown. In part, this is because of the poor characteriz
Autor:
Patrick J. Riss, Valentina Ferrari, Tim D. Fryer, Yoshiro Shiba, John Suckling, Andrea M. Santangelo, Roger Tait, Franklin I. Aigbirhio, Angela C. Roberts, Young T. Hong, Hannah F. Clarke, Stephen J. Sawiak
Genetic variation in the serotonin transporter gene (SLC6A4) is associated with vulnerability to affective disorders and pharmacotherapy efficacy. We recently identified sequence polymorphisms in the common marmoset SLC6A4 repeat region (AC/C/G and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b5af58f01283c780e39938f1dc317c
Autor:
Jorge L, Zeredo, Shaun K L, Quah, Chloe U, Wallis, Laith, Alexander, Gemma J, Cockcroft, Andrea M, Santangelo, Jing, Xia, Yoshiro, Shiba, Jeffrey W, Dalley, Rudolf N, Cardinal, Angela C, Roberts, Hannah F, Clarke
Publikováno v:
The Journal of Neuroscience
High-trait anxiety is a risk factor for the development of affective disorders and has been associated with decreased cardiovascular and behavioral responsivity to acute stressors in humans that may increase the risk of developing cardiovascular dise