Výsledky vyhledávání - "Hannah E. Silva"

Cocaine craving during protracted withdrawal requires PKCε priming within vmPFC

Autor: Karen K. Szumlinski, Melissa G. Wroten, Bailey W. Miller, Philip A. Vieira, Christina B. Shin, Osnat Ben-Shahar, Tod E. Kippin, Arianne D. Sacramento, Hannah E. Silva

Publikováno v: Addiction Biology. 22:629-639

In individuals with a history of drug taking, the capacity of drug-associated cues to elicit indices of drug craving intensifies or incubates with the passage of time during drug abstinence. This incubation of cocaine craving, as well as difficulties

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1d16efbfa7bfb277c1094970c13c4de
https://doi.org/10.1111/adb.12354

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Deficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administration

Autor: Sierra M. Webb, Kyle L. Ploense, Amanda L. Caruana, Arianne D. Sacramento, Karen K. Szumlinski, Tod E. Kippin, Osnat Ben-Shahar, Hannah E. Silva, Melissa G. Wroten, Bailey W. Miller, Evan Gordon, Jennifer Ditzhazy

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(2)

Anomalies in prefrontal cortex (PFC) function are posited to underpin difficulties in learning to suppress drug-seeking behavior during abstinence. Because group 1 metabotropic glutamate receptors (mGluRs) regulate drug-related learning, we assayed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf4dcd1302004452d37f6ecb82402a9
https://pubmed.ncbi.nlm.nih.gov/23303930

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