Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hannah E. Kinne"'
Autor:
Balraj Singh, Vanessa N. Sarli, Ryan D. Milligan, Hannah E. Kinne, Anna Shamsnia, Laura J. Washburn, Sridevi Addanki, Anthony Lucci
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2036
We treated highly metabolically adaptable (SUM149-MA) triple-negative inflammatory breast cancer cells and their control parental SUM149-Luc cell line with JQ1 for long periods to determine its efficacy at inhibiting therapy-resistant cells. After 20
Autor:
Balraj Singh, Vanessa N. Sarli, Ryan D. Milligan, Hannah E. Kinne, Anna Shamsnia, Laura J. Washburn, Anthony Lucci
Background: Cell culture models of cancer typically favor proliferative but therapy-sensitive cells because body-like selection pressures are absent. To address this limitation of cell culture, we previously described a function-based selection strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d667d3be71bc9a2dea4ceda9b401e31
https://doi.org/10.21203/rs.3.rs-1832724/v1
https://doi.org/10.21203/rs.3.rs-1832724/v1
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159072 (2016)
We have previously shown that only 0.01% cells survive a metabolic challenge involving lack of glutamine in culture medium of SUM149 triple-negative Inflammatory Breast Cancer cell line. These cells, designated as SUM149-MA for metabolic adaptability
Externí odkaz:
https://doaj.org/article/c884f3f26bd64bbebf45832ac7c2c275
Publikováno v:
Oncotarget
Progenitor-like cancer cells that can survive in reversible quiescence when faced with various challenges in the body are often behind disease progression. A lack of glutamine in culture medium, which eliminates >99.9% of proliferating SUM149 triple-
Publikováno v:
Oncotarget. 13:1272-1272
Publikováno v:
Cancer Research. 77:P3-07
We have recently developed a usable model of panresistance in triple-negative breast cancer. We have shown that only 0.01% cells survive a metabolic challenge involving lack of glutamine in culture medium of SUM149 triple-negative Inflammatory Breast
Autor:
Laura J. Washburn, Balraj Singh, Hannah E. Kinne, Mark Olsen, Ryan D. Milligan, Anthony Lucci
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 7, p e0159072 (2016)
PLoS ONE, Vol 11, Iss 7, p e0159072 (2016)
We have previously shown that only 0.01% cells survive a metabolic challenge involving lack of glutamine in culture medium of SUM149 triple-negative Inflammatory Breast Cancer cell line. These cells, designated as SUM149-MA for metabolic adaptability
Autor:
Mark Olsen, Balraj Singh, Ryan D. Milligan, Hannah E. Kinne, Anthony Lucci, Laura J. Washburn
Publikováno v:
Cancer Research. 76:2416-2416
Cancer is an evolution-like process. Effectively dealing with the currently untreatable component of breast cancer (the cells that drive metastasis) is vital. In this regard, we have developed a model of panresistant cancer cells that allows us to ev
Publikováno v:
Cancer Research. 75:1719-1719
A major obstacle in developing effective therapies against solid tumors stems from an inability to adequately model the rare subpopulation of panresistant cancer cells that may often drive the disease. We propose a strategy for optimally modeling hig