Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?

Autor: Stephanie W. Vrede, Hannah Donkers, Casper Reijnen, Anke Smits, Nicole C.M. Visser, Peggy M. Geomini, Huy Ngo, Dennis van Hamont, Brenda M. Pijlman, Maria Caroline Vos, Marc P.L.M. Snijders, Roy Kruitwagen, Ruud L.M. Bekkers, Khadra Galaal, Johanna M.A. Pijnenborg

Publikováno v: Journal of Obstetrics and Gynaecology, Vol 44, Iss 1 (2024)

Background In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour aggressiveness, or also impact response to ad

Externí odkaz: https://doaj.org/article/47c1e1cca20140df8cdf7eeb83eb6baa

Obesity and visceral fat: Survival impact in high-grade endometrial cancer

Autor: Khadra Galaal, Hannah Donkers, Johanna M.A. Pijnenborg, Ingfrid S. Haldorsen, John McGrane, Ruud L.M. Bekkers, Kristine Eldevik Fasmer

Publikováno v: European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 425-432
European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 425-432. Elsevier
European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, pp. 425-432

Background: Obesity is an important risk factor for the development of endometrial cancer (EC). Recent data showed that body fat distribution might be more relevant than Body Mass Index (BMI). High visceral fat percentage was shown to be an independe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aaf2f1c871a34a7218ca22404c7d60f
https://hdl.handle.net/2066/230097

Real World Patterns of PSA Response and Survival with Abiraterone and Enzalutamide in Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Autor: John McGrane, Michael Rowe, Stuart Walter, Ayesha Hidayat, Hannah Donkers, Andrew Browne, Timothy Norris, Adam Pollard, Deborah Victor

Publikováno v: Clinical Oncology and Research. :1-6

Background: We investigated our institution’s mCRPC enzalutamide or abiraterone patients examining PSA responses and impact of sequencing of these drugs. Methods: All enzalutamide / abiraterone mCRPC patients (2011-2018) were included. Rates of PSA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79d0c2f97458d69714ed5df8c71f51e3
https://doi.org/10.31487/j.cor.2020.07.11

The impact of socioeconomic deprivation on mortality in cervical cancer patients in Cornwall (England)

Autor: Hannah Donkers, Ruud L.M. Bekkers, Khadra Galaal, John McGrane, Antonio Eleuteri, Panagiotis Giamougiannis

Publikováno v: European Journal of Cancer Care, 30(5):e13463. Wiley

Objectives To assess the association between risk factors, including socioeconomic deprivation, and mortality, recurrence and chemo- or radiation toxicity in cervical cancer patients. Methods Retrospective study of cervical cancer patients diagnosed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839849c28b6d08b7cc80581e66d7b1f5
https://doi.org/10.1111/ecc.13463

Systematic review on socioeconomic deprivation and survival in endometrial cancer

Autor: K. Galaal, Hannah Donkers, Leon F.A.G. Massuger, Ruud L.M. Bekkers

Publikováno v: Cancer Causes & Control, 30, 9, pp. 1013-1022
Cancer Causes & Control, 30, 1013-1022

Contains fulltext : 208574.pdf (Publisher’s version ) (Open Access) PURPOSE: The primary objectives in this review were to (1) assess the association between socioeconomic deprivation and survival in endometrial cancer patients (2) investigate if t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14323e324bacedd5457b7291f7279d1e
https://hdl.handle.net/2066/208574