Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hannah Cheung"'
Autor:
Yu Liu, Jianjun Zhang, Lin Li, Guangliang Yin, Jianhua Zhang, Shan Zheng, Hannah Cheung, Ning Wu, Ning Lu, Xizeng Mao, Longhai Yang, Jiexin Zhang, Li Zhang, Sahil Seth, Huang Chen, Xingzhi Song, Kan Liu, Yongqiang Xie, Lina Zhou, Chuanduo Zhao, Naijun Han, Wenting Chen, Susu Zhang, Longyun Chen, Wenjun Cai, Miaozhong Shen, Ningzhi Xu, Shujun Cheng, Huanming Yang, J. Jack Lee, Arlene Correa, Junya Fujimoto, Carmen Behrens, Chi-Wan Chow, William N. William, John V. Heymach, Waun Ki Hong, Stephen Swisher, Ignacio I. Wistuba, Jun Wang, Dongmei Lin, Xiangyang Liu, P. Andrew Futreal, Yanning Gao
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and
Externí odkaz:
https://doaj.org/article/b47899a5b32046278f07cf214de45ffc
Interactions with our community and social environment play a significant role in our overall health and wellbeing and are considered Social Determinants of Health (SDOH). One SDOH that impacts Cumberland County, North Carolina is the number of child
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130a1e97b30c2fd62a087352f241c9be
Autor:
Wen Ting Liao, Jian Hu, Jianhua Zhang, Melody Wang, Adam T. Boutin, Eduardo Vilar, Gerald C. Chu, Hannah Cheung, Tatiana Karpinets, Y. Alan Wang, Scott Kopetz, Soyoon Sarah Hwang, Xingzhi Song, Ronald A. DePinho, Shan Jiang, Andrew Futreal, Lawrence N. Kwong, Kyle Chang
Publikováno v:
Genes & Development. 31:370-382
Human colorectal cancer (CRC) is a major cause of cancer mortality and frequently harbors activating mutations in the KRAS gene. To understand the role of oncogenic KRAS in CRC, we engineered a mouse model of metastatic CRC that harbors an inducible
Autor:
Deborah I. Ritter, Patrick A. Thompson, Jonathan S. Berg, Caleb F. Davis, Sharon E. Plon, Katherine Haines, Richard A. Gibbs, David A. Wheeler, Chester W. Brown, Hannah Cheung, Ching C. Lau
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics
Purpose We applied whole genome sequencing to children diagnosed with neoplasms and found to carry apparently balanced constitutional translocations, to discover novel genic disruptions. Methods We applied SV calling programs CREST, Break Dancer, SV-
Autor:
Adam T, Boutin, Wen-Ting, Liao, Melody, Wang, Soyoon Sarah, Hwang, Tatiana V, Karpinets, Hannah, Cheung, Gerald C, Chu, Shan, Jiang, Jian, Hu, Kyle, Chang, Eduardo, Vilar, Xingzhi, Song, Jianhua, Zhang, Scott, Kopetz, Andrew, Futreal, Y Alan, Wang, Lawrence N, Kwong, Ronald A, DePinho
Publikováno v:
Genesdevelopment. 31(4)
Here, Boutin et al. investigated the role of oncogenic KRAS in colorectal cancer (CRC). They generated a mouse model of metastatic CRC that harbors an inducible oncogenic Kras allele (Krasmut) and conditional null alleles of Apc and Trp53 (iKAP), whi
Autor:
Carmen Behrens, Arlene M. Correa, Lina Zhou, Hannah Cheung, Susu Zhang, Junya Fujimoto, Sahil Seth, Huang Chen, Jianhua Zhang, Shan Zheng, Ning Lu, Naijun Han, Jiexin Zhang, Kan Liu, Yu Liu, Stephen G. Swisher, Yanning Gao, William N. William, Chi Wan Chow, Ning Wu, P. Andrew Futreal, Xizeng Mao, Chen Longyun, Ignacio I. Wistuba, Lin Li, Ningzhi Xu, Guangliang Yin, Shujun Cheng, W Q Chen, J. Jack Lee, Xiangyang Liu, Jun Wang, Miaozhong Shen, Wenjun Cai, Yong-qiang Xie, Jianjun Zhang, L. Yang, Huanming Yang, Xingzhi Song, Li Zhang, Dongmei Lin, Chuanduo Zhao, Waun Ki Hong, John V. Heymach
Publikováno v:
Nature Communications
Liu, Y, Zhang, J, Li, L, Yin, G, Zhang, J, Zheng, S, Cheung, H, Wu, N, Lu, N, Mao, X, Yang, L, Zhang, J, Zhang, L, Seth, S, Chen, H, Song, X, Liu, K, Xie, Y, Zhou, L, Zhao, C, Han, N, Chen, W, Zhang, S, Chen, L, Cai, W, Li, L, Shen, M, Xu, N, Cheng, S, Yang, H, Lee, J J, Correa, A, Fujimoto, J, Behrens, C, Chow, C-W, William, W N, Heymach, J V, Hong, W K, Swisher, S, Wistuba, I I, Wang, J, Lin, D, Liu, X, Futreal, P A & Gao, Y 2016, ' Genomic heterogeneity of multiple synchronous lung cancer ', Nature Communications, vol. 7, 13200 . https://doi.org/10.1038/ncomms13200
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Liu, Y, Zhang, J, Li, L, Yin, G, Zhang, J, Zheng, S, Cheung, H, Wu, N, Lu, N, Mao, X, Yang, L, Zhang, J, Zhang, L, Seth, S, Chen, H, Song, X, Liu, K, Xie, Y, Zhou, L, Zhao, C, Han, N, Chen, W, Zhang, S, Chen, L, Cai, W, Li, L, Shen, M, Xu, N, Cheng, S, Yang, H, Lee, J J, Correa, A, Fujimoto, J, Behrens, C, Chow, C-W, William, W N, Heymach, J V, Hong, W K, Swisher, S, Wistuba, I I, Wang, J, Lin, D, Liu, X, Futreal, P A & Gao, Y 2016, ' Genomic heterogeneity of multiple synchronous lung cancer ', Nature Communications, vol. 7, 13200 . https://doi.org/10.1038/ncomms13200
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Multiple synchronous lung cancers (MSLCs) present a clinical dilemma as to whether individual tumours represent intrapulmonary metastases or independent tumours. In this study we analyse genomic profiles of 15 lung adenocarcinomas and one regional ly
Autor:
Courtney D. DiNardo, Sarah A. Bannon, Lucy A. Godley, Hannah Cheung, Jane E. Churpek, Maureen E. Mork, Koichi Takahashi, Anna Franklin, Jordan S. Orange, Andrew Futreal, Meselle Jeff-Eke, Alison A. Bertuch, Guillermo Garcia-Manero, Mark J. Routbort, Keyur P. Patel, Jeffrey L. Jorgensen, Mary Armanios, Emily M. Mace, Steve Kornblau, Kapil N. Bhalla
Publikováno v:
Clinical lymphoma, myelomaleukemia. 16(7)
Introduction Although multiple predispositions to hematologic malignancies exist, evaluations for hereditary cancer syndromes (HCS) are underperformed by most hematologist/oncologists. Criteria for initiating HCS evaluation are poorly defined, and re
Autor:
Courtney W. Hudgens, Alexander J. Lazar, Padmanee Sharma, Mariana Petaccia de Macedo, Pei-Ling Chen, Rodabe N. Amaria, Michael A. Davies, Ignacio I. Wistuba, Lynda Chin, Vancheswaran Gopalakrishnan, Andrew Futreal, Wei-Shen Chen, Haven R. Garber, Patrick Hwu, Hannah Cheung, Karen C. Dwyer, Michael T. Tetzlaff, James P. Allison, Alexandre Reuben, Cara Haymaker, Hong Jiang, John P. Miller, Sapna Pradyuman Patel, Scott E. Woodman, Zachary A. Cooper, Christine N. Spencer, Jennifer A. Wargo, Jianhua Zhang, Jason Roszik, Peter A. Prieto, Jacob Austin-Breneman, Xizeng Mao
Publikováno v:
Cancer Research. 76:2392-2392
There have been significant advances in the treatment of metastatic melanoma through targeted and immunotherapy, however a significant proportion of patients still progress on these regimens with many experiencing mixed responses. Intense research ef
Autor:
Sahil Seth, Hannah Cheung, Jianjun Zhang, Dongmei Lin, Xingzhi Song, Xiangyang Liu, Lin Li, Guangliang Yin, Shujun Cheng, Andrew Futreal, Xizeng Mao, Jiexin Zhang, Yanning Gao, Yu Liu, Jianhua Zhang
Publikováno v:
Cancer Research. 75:2982-2982
Background: Genomic heterogeneity of lung cancers from different patients has been well documented, reflecting distinct genetic background and different carcinogen exposures. On the other hand, our recent study has demonstrated limited heterogeneity
Autor:
Sharon E. Plon, Deborah I. Ritter, Bradford C. Powell, Donna M. Muzny, Jason Saliba, David A. Wheeler, Ryan C. Zabriskie, Stephanie C. Hicks, Jeffrey G. Reid, Richard A. Gibbs, Hannah Cheung, Marek Kimmel
Publikováno v:
Cancer Research. 74:A8-A8
The underlying genetic basis of many childhood cancers remains largely unknown, which places a significant focus on the discovery and understanding of cancer susceptibility genes. Even genetic predisposition of the most common childhood cancer, acute